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zs200311

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感受浪漫,品味高雅

[交流] 【分享】维生素PQQ【已搜无重复】

看过这样一篇报道:
2003年4月24日,日本物理化学研究所科学家宣布,他们发现一种水溶性B族维生素PQQ,缺乏这种物质的实验鼠会出现繁殖能力低下等现象。他们推测,缺乏PQQ对人类也有相同的影响。
这是1948年以来人们首次发现新的维生素。如果得到世界卫生组织的认定,这将成为第14种维生素。这也是1910年东京帝国大学(现东京大学)教授铃木梅太郎第一次发现维生素B1后,日本科学家发现的第二种维生素。
1979年美国得克萨斯大学的研究人员在细菌中找到了PQQ的踪迹,加利福尼亚大学的实验证明,PQQ摄入不足的实验鼠繁殖能力低下,但他们一直没能证明这是一种新的维生素。
日本物理化学研究所加藤忠史研究员领导的研究小组在研究与躁郁循环性疾病相关基因的作用时,意外发现了一种动物和人体细胞内分解赖氨酸不可缺少的酶,这种酶如果不与PQQ结合就难以发挥作用。研究人员根据PQQ和酶结合在一起参与新陈代谢的特性,断定它是一种新的维生素。
日本传统的大豆发酵食品“纳豆”富含PQQ,另外西芹、绿茶、胡椒粉、番木瓜等也含有这种维生素。

不知道这篇报道的真实成分有多少,大家对这方面有了解吗?

[ Last edited by signal023 on 2008-6-3 at 22:02 ]
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akangln

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化学反应过渡态的计算方法
王沁泌, 蒋华良 - 化学进展, 1997 - 维普资讯
... 在细菌中催化甲醇氧化成甲醛。Salisbury等从细菌中分离出它的氧化还原辅酶,
其系统命名为2,7,9一三羟基一1H一吡咯并[2,3一f]一喹啉一4 5一二酮,
半系统名称为吡咯并喹啉苯醒(pyrroloquinolinequinone—PQQ,见图1)。对PQQ ...
--------------
真菌漆酶及其应用 - 每组 2 个 »
钞亚鹏, 钱世钧 - 生物工程进展, 2001 - 维普资讯
... 而某些酶蛋白的辅基有例外的情况。Karhulien等的研究指出,Phlebia radiata
产生的漆酶中只含有2个铜原子,另外还有一分子的有机小分子辅基吡咯喹琳醌(
pyrroloquinolinequinone,PQQ),该辅基在分子中扮演类似llJ型铜原子的功能。1997 ...
3楼2006-10-24 18:26:26
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akangln

木虫 (著名写手)

1

真不知道这东东,在google学术上查了一下,还真有这家伙^_^
… between Electrodes and NAD (P)+-Dependent Enzymes Using Pyrroloquinolinequinone-Enzyme Electrodes in … - 每组 2 个 »
I Willner, A Riklin - Analytical Chemistry, 1994 - pubs.acs.org
... NAD(P)+-Dependent Enzymes Using Pyrroloquinolinequinone-Enzyme Electrodes in a
Self-Assembled Monolayer Configuration: Design of a New Class of Amperometric
Biosensors ... Pyrroloquinolinequinone (PQQ, 1) was covalently linked to a self-assembled ...
被引用次数:52 - 相关文章 - 网页搜索

Evidence for pyrroloquinolinequinone as the carbonyl cofactor in lysyl oxidase by absorption and … - 每组 3 个 »
PR Williamson, RS Moog, DM Dooley, HM Kagan - Journal of Biological Chemistry, 1986 - jbc.org
... THE JOURNAL OF BIOLOGICAL CHEMISTRY Printed in U: S. A. Evidence for
Pyrroloquinolinequinone as the Carbonyl Cofactor in Lysyl Oxidase by Absorption
and Resonance Raman Spectroscopy* (Received ... PQQ FIG. 1. Structure of ...
被引用次数:7 - 相关文章 - 网页搜索

Evidence for Methoxatin (Pyrroloquinolinequinone) as the Cofactor in Bovine Plasma Amine Oxidase … - 每组 5 个 »
RS Moog, MA McGuirl, CE Cote, DM Dooley - Proceedings of the National Academy of Sciences, 1986 - pnas.org
... USA Vol. 83, pp. 8435-8439, November 1986 Chemistry Evidence for methoxatin
(pyrroloquinolinequinone) as the cofactor in bovine plasma amine oxidase from resonance
Raman spectroscopy ... Vibrational frequencies of normal Abbreviations: PQQ, ...
被引用次数:4 - 相关文章 - 网页搜索

C-4 and C-5 adducts of cofactor PQQ (pyrroloquinolinequinone). Model studies directed toward the … - 每组 2 个 »
S Itoh, M Ogino, Y Fukui, H Murao, M Komatsu, Y … - Journal of the American Chemical Society, 1993 - pubs.acs.org
Page 1. 9960 J. Am. Chem. Soc. 1993, 115, 9960-9967 C-4 and C-5 Adducts of Cofactor
PQQ (Pyrroloquinolinequinone). Model Studies Directed toward the Action of Quinoprotein
Methanol Dehydrogenase? Shinobu Itoh,' Masaki Ogino, Yoshifumi Fukui ...
被引用次数:4 - 相关文章 - 网页搜索

Pyrroloquinolinequinone enzyme electrode based on the coupling of methanol dehydrogenase to a … - 每组 2 个 »
S Zhao, RB Lennox - Analytical Chemistry, 1991 - pubs.acs.org
... in press. RECEIVED for review August 7,1990. Accepted February 21, 1991. 1986, 90,
207. 384, 25. (29) aueckauf, E. 7ians. Fl”y Soc. 1065, 51, 34. Pyrroloquinolinequinone
Enzyme Electrode Based on the Coupling of Methanol Dehydrogenase to a ...
被引用次数:4 - 相关文章 - 网页搜索

Photochemical Reactions of Coenzyme PQQ (Pyrroloquinolinequinone) and Analogues with Benzyl Alcohol … - 每组 2 个 »
S Fukuzumi, S Itoh, T Komori, T Suenobu, A Ishida, … - JOURNAL-AMERICAN CHEMICAL SOCIETY, 2000 - pubs.acs.org
... 10.1021/ja001351g S0002-7863(00)01351-2 Web Release Date: August 17, 2000. Copyright ©
2000 American Chemical Society Photochemical Reactions of Coenzyme PQQ
(Pyrroloquinolinequinone) and Analogues with Benzyl Alcohol Derivatives via ...
被引用次数:3 - 相关文章 - 网页搜索

Synthesis of Pyrroloquinolinequinone Analogs. Molecular Structure and Moessbauer and Magnetic … - 每组 2 个 »
L Tommasi, L Shechter-Barloy, D Varech, JP … - Inorganic Chemistry, 1995 - pubs.acs.org
1514 Inorg. Chem. 1995,34, 1514-1523 Synthesis of Pyrroloquinolinequinone Analogs. ...
CN (41, wherein L2H, L3H3, and L4H are analogs of pyrroloquinolinequinone or methoxatin
(PQQ), have been synthesized and studied. 2 crystallizes in the triclinic ...
被引用次数:2 - 相关文章 - 网页搜索

… of imidazolopyrroloquinoline, a main reaction product of pyrroloquinolinequinone(PQQ) and L- …
T ISHIDA, Y IN, E KAWAMOTO, T AMANO, J KANAYAMA, M … - Chemical and pharmaceutical bulletin, 1996 - cat.inist.fr
X-ray molecular and crystal structure of imidazolopyrroloquinoline, a main reaction
product of pyrroloquinolinequinone(PQQ) and L-tryptophan in vitro. T ISHIDA, Y IN,
E KAWAMOTO, T AMANO, J KANAYAMA, M DOI, T IWASHITA, K NOMOTO Chemical and ...
被引用次数:1 - 相关文章 - 网页搜索

The Cofactor Pyrroloquinoline Quinone - 每组 3 个 »
JA Duine - Annual Review of Nutrition, 1990 - nutr.annualreviews.org
... Rev. Nutr. 1990. 10.’297-318 Copyright © 1990 by Annual Reviews Inc. All rights
reserved THE COFACTOR PYRROLOQUINOLINEQUINONE J. A. Duine, R. A. van der Meer, and
B. W. Groen Department of Microbiology and Enzymology, Delft University of Technology ...
被引用次数:2 - 相关文章 - 网页搜索

Structure of the 2, 4-dinitrophenylhydrazine adduct of pyrroloquinolinequinone (PQQ) dimethyl ethyl … - 每组 4 个 »
H van Koningsveld, JC Jansen, JA Jongejan, JJ … - Crystal Structure Communications - dx.doi.org
... Volume 41 Part 1 Pages 89-92 January 1985 Structure of the 2,4-dinitrophenylhydrazine
adduct of pyrroloquinolinequinone (PQQ) dimethyl ethyl triester, C 24 H 18 N 6 O
11. ... Structure of the 2,4-Dinitrophenylhydrazine Adduct of Pyrroloquinolinequinone ...
相关文章 - 网页搜索
2楼2006-10-24 18:24:28
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