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An assumption often made is that diverse structures will result in diverse outcomes across many assays, but few studies address this question directly (49¨C53). Likewise, our recent analysis (48) did not account for the distinction between individual and groupwise compound performance. The availability of data from large-scale experiments (48) and public databases provides an opportunity to measure set-based performance quantitatively, rather than measuring success by finding a few ¡°special¡± compounds. |
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