24小时热门版块排行榜    

Znn3bq.jpeg
汕头大学海洋科学接受调剂
查看: 1143  |  回复: 9
当前主题已经存档。
当前只显示满足指定条件的回帖,点击这里查看本话题的所有回帖

ermopi

金虫 (正式写手)

[交流] 这一篇重点介绍了实际应用的pd催化C-N&C-O键的形成反应!

这一篇重点介绍了实际应用的pd催化C-N&C-O键的形成反应!
Topics in Current Chemistry,Vol. 219

Practical Palladium Catalysts for C-N and C-O Bond Formation

    The development of new palladium catalysts for the arylation of amines and alcohols with aryl halides and sulfonates is reviewed. Initial systems as well as mechanistic issues are discussed briefly,while subsequent generations of catalysts are described in greater detail.For these later generations of catalysts, substrate scope and limitations are also discussed.The review is organized by substrate class. Modifications and improvements in technical aspects of reaction development are described where appropriate. In addition, applications of this technology toward natural product synthesis, new synthetic methodology, and medicinal chemistry are chronicled. This review is organized in a manner that is designed to be useful to the synthetic
organic chemist.

Keywords. Amination, Arylation, Catalyst, Ligand, Palladium

1 Introduction . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 133
2 Palladium-Catalyzed Amine Arylation . . . . . . . . . . . . . . . . 134
2.1 Initial Systems . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 134
2.2 N-Arylation of Secondary Amines . . . . . . . . . . . . . . . . . . . 136
2.2.1 Reaction of Cyclic Secondary Amines with Aryl Bromides . . . . . 136
2.2.2 Reaction of Secondary Amines with Aryl Bromides . . . . . . . . . 143
2.2.3 Reaction of Diarylamines with Aryl Bromides . . . . . . . . . . . . 148
2.2.4 Reaction of Secondary Amines with Aryl Iodides . . . . . . . . . . 150
2.2.5 Reaction of Cyclic Secondary Amines with Aryl Chlorides . . . . . 151
2.2.6 Reaction of Acyclic Secondary Amines with Aryl Chlorides . . . . 154
2.2.7 Reaction of Cyclic Amines with Aryl Sulfonates . . . . . . . . . . . 157
2.2.8 Reaction of Secondary Acyclic Amines with Aryl Sulfonates . . . . 159
2.3 N-Arylation of Primary Amines . . . . . . . . . . . . . . . . . . . . 160
2.3.1 Reaction of Primary Aliphatic Amines with Aryl Bromides . . . . . 160
2.3.2 Reaction of Primary Aromatic Amines with Aryl Bromides . . . . 165
2.3.3 Reaction of Primary Amines with Aryl Iodides . . . . . . . . . . . 171
2.3.4 Reaction of Primary Aliphatic Amines with Aryl Chlorides . . . . . 172
2.3.5 Reaction of Primary Arylamines with Aryl Chlorides . . . . . . . . 174
2.3.6 Reaction of Primary Aliphatic Amines with Aryl Sulfonates . . . . 176
2.3.7 Reaction of Primary Arylamines with Aryl Sulfonates . . . . . . . . 177
2.4 Arylation of Ammonia Equivalents . . . . . . . . . . . . . . . . . . 179
2.5 Arylation of Amides and Carbamates . . . . . . . . . . . . . . . . . 183
2.6 Arylation of Nitrogen-Containing Heterocycles . . . . . . . . . . . 184
2.7 Arylation of Other Nitrogen Substrates . . . . . . . . . . . . . . . . 187
2.8 Heteroaryl Halides in the Pd-Catalyzed Amine Arylation . . . . . . 190
2.9 Intramolecular Arylation of Amines and Amides . . . . . . . . . . 194
2.9.1 Intramolecular Arylation of Amines . . . . . . . . . . . . . . . . . 194
2.9.2 Intramolecular Arylation of Amides . . . . . . . . . . . . . . . . . 197
3 Palladium-Catalyzed Alcohol Arylation . . . . . . . . . . . . . . . 198
3.1 Reaction of Aliphatic Alcohols . . . . . . . . . . . . . . . . . . . . . 198
3.2 Reaction of Phenol Derivatives . . . . . . . . . . . . . . . . . . . . 201
3.3 Intramolecular Arylation of Alcohols . . . . . . . . . . . . . . . . . 203
4 Conclusions . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 204
5 References . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 205

[ Last edited by wxwdoctor on 2007-3-25 at 19:46 ]
回复此楼
一切随缘吧!
已阅   回复此楼   关注TA 给TA发消息 送TA红花 TA的回帖

rabbit7708

荣誉版主 (职业作家)

心虫

1


刚看到,再加一个!:)
化学学科——催化专版欢迎您!:) http://emuch.net/bbs/forumdisplay.php?fid=190 常来看看哟!:)
8楼2006-10-22 12:53:57
已阅   回复此楼   关注TA 给TA发消息 送TA红花 TA的回帖
查看全部 10 个回答

feieronly

金虫 (初入文坛)

0.5

为什么我下载后无法解压啊?郁闷!
4楼2006-10-08 10:14:46
已阅   回复此楼   关注TA 给TA发消息 送TA红花 TA的回帖

我是阿广

木虫 (职业作家)

欲将心事付瑶琴······

1

太好了
非常感谢ermopi
Theoryiswhenyouknoweverythingbutnothingworks.
5楼2006-10-08 11:09:08
已阅   回复此楼   关注TA 给TA发消息 送TA红花 TA的回帖

hantang

木虫 (小有名气)

1

谢谢 ! 很有价值!
天行健,君子以自强不息。
6楼2006-10-22 11:54:40
已阅   回复此楼   关注TA 给TA发消息 送TA红花 TA的回帖
普通表情 高级回复 (可上传附件)
最具人气热帖推荐 [查看全部] 作者 回/看 最后发表
[考研] 294求调剂 +3 淡然654321 2026-04-15 3/150 2026-04-15 13:13 by Llllss12
[考研] 22408 312求调剂 +17 门路摸摸 2026-04-14 18/900 2026-04-15 13:11 by 西北望—风沙
[考研] 材料工程281还有调剂机会吗 +43 xaw. 2026-04-11 44/2200 2026-04-15 12:46 by 西北望—风沙
[考研] 290求调剂 +21 luoziheng 2026-04-10 23/1150 2026-04-14 15:49 by zs92450
[考研] 人工智能320调剂08工类还有机会吗 +18 振—TZ 2026-04-10 19/950 2026-04-14 10:34 by screening
[考研] 材料085601调剂 +32 何润采123 2026-04-10 34/1700 2026-04-14 08:47 by 木木mumu~
[考研] 考研求调剂 +12 子木呐 2026-04-12 13/650 2026-04-14 01:19 by 王珺璞
[考研] 一志愿西交机械专硕求调剂 +9 求上岸的小王 2026-04-10 9/450 2026-04-13 16:08 by jiangguiquan11
[考研] 一志愿双非085400电子信息344 求调剂,对材料和化学方向也感兴趣 +12 无情的小羊 2026-04-09 13/650 2026-04-13 14:17 by 张zhihao
[考研] 291求调剂 +11 关忆北. 2026-04-09 12/600 2026-04-12 10:32 by 逆水乘风
[考研] 280求调剂 +7 兮兮夜夜 2026-04-09 10/500 2026-04-12 00:33 by 蓝云思雨
[考研] 359求调剂 +5 胃痉挛累了 2026-04-11 5/250 2026-04-11 19:55 by lbsjt
[考研] 调剂 +5 文道星台 2026-04-11 5/250 2026-04-11 15:01 by 凯凯要变帅
[考研] 机械专硕270求调剂,接受跨专业 +12 老师看看我吧aba 2026-04-09 14/700 2026-04-11 10:21 by laoshidan
[考研] 22408 327分求调剂 +4 韵风kon 2026-04-10 4/200 2026-04-11 09:51 by 猪会飞
[考研] 070300化学 求调剂 +13 73372112 2026-04-08 13/650 2026-04-09 20:22 by maddjdld
[考研] 337求调剂 +4 Gky09300550, 2026-04-09 4/200 2026-04-09 17:18 by 帕尔马拉特
[考研] 083200 初试305分 求调剂 暂不考虑跨专业 +15 Claireyyyy 2026-04-09 15/750 2026-04-09 16:11 by zhuimr
[考研] 086004 求调剂 309 +7 Yin DY 2026-04-08 7/350 2026-04-09 13:59 by Delta2012
[考研] 331求调剂 +5 luoxin0706. 2026-04-08 5/250 2026-04-08 22:15 by zhouyuwinner
信息提示
请填处理意见