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[½»Á÷] Oslo-PhD Research Fellow in Organic Chemistry- (ref. no. 2011/6099) ÒÑÓÐ2È˲ÎÓë

PhD Research Fellow in Organic Chemistry- (ref. no. 2011/6099)

http://uio.easycruit.com/vacancy/554590/64291?iso=no

Department of Chemistry
PhD Research Fellow in Organic Chemistry- (ref. no. 2011/6099)
A position as PhD Research Fellow is available at the Department of Chemistry, University of Oslo (http://www.kjemi.uio.no/), within the Synthesis and Molecular Structure research group.

The fellowship is for a period of up to 3 years. Starting date no later than 15.08.2011.

Job description

The project is entitled "Design, synthesis and biological evaluation of 8-oxoguanine derivatives as potential inhibitors of DNA glycosylases - possible adjuvants in cancer treatment" and is financed by MLSUiO. The aim of the project is design and synthesis of novel inhibitors of human DNA glycosylases involved in the repair of oxidative damages in DNA. Such inhibitors may enhance the thera-peutic effect of cancer radiotherapy and chemotherapy since these two treatment protocols are based on challenging the DNA repair capacity of the cancer cells, partly by imposing high concentrations of DNA damage in the tumour cells. The candidate will focus on the synthesis of potential inhibitors and the project will be conducted in in close cooperation with Dr. Bjørn Dalhus and co-workers (Institute for Clinical Biochemistry & Institute for Medical Microbiology, National Hospital).

Requirements

Applicants must hold a Master¡¯s degree or equivalent in chemistry.

The selected candidate should be motivated, talented, and curiosity driven individual with a strong background in organic chemistry, especially with organic synthesis and chromatographic and spectroscopic methods for separation and structure elucidation of organic compounds. Previous experience in heterocyclic chemistry and nucleside analog synthesis, may be emphasized, but is not a prerequisite.

The purpose of the fellowship is research training leading to the successful completion of a doctoral degree. The fellowship requires admission to the research training program of the Faculty of Mathematics and Natural Sciences. An approved plan for the research training must be submitted no later than two months after taking up the position, and admission approved within three months after the date of commencement. For more information see:

http://www.uio.no/admhb/reglhb/p ... nstermcondition.xml

and

http://www.mn.uio.no/english/res ... ary-regulations.pdf

A good command of English is required.

Pay grade:

PhD Research Fellow (SKO 1017), pay grade: 48 - 56 (NOK 383 700 ¨C 440 500 per year)

The application must include:

Application letter
CV (summarizing education, positions and academic work - scientific publications)
Copies of educational certificates, transcript of records and letters of recommendation
List of publications and academic work that the applicant wishes to be considered by the evaluation committee
Names and contact details of 2-3 referees (name, relation to candidate, e-mail and telephone number)
Foreign applicants are advised to attach an explanation of their University¡¯s grading system. Please remember that all documents should be in English or a Scandinavian language.

The University of Oslo has an agreement for all employees, aiming to secure rights to research results a.o.

In accordance with the University of Oslo´s equal opportunity policy, we invite applications from all individuals regardless of gender or ethnicity.

Region:
Oslo
Application deadline:
1 June, 2011
Location:
Blindern, Oslo
Reference number:
2011/6099
Home page:
http://www.kjemi.uio.no
Contacts:
Professor Lise Lotte Gundersen
Telephone: +47 22857019
Mobile: +47 93083692
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