| 查看: 1099 | 回复: 9 | |||
| 当前主题已经存档。 | |||
[交流]
Handbook of Drug Screening
|
|||
|
Handbook of Drug Screening Posted by :: Ivanhk | Date :: Sep 14, 2006 20:45:00 Handbook of Drug Screening edited byRamakrishna Seethala and Prabhavathi Fernandes ISBN: 0824741447 | year 2001 | English 520pages | pdf | size:8,62Mb This state-of-the-art reference provides comprehensive coverage of current screening techniques, modern technologies, and high-capacity instrumentation for increased productivity in the development and discovery of new drugs, chemical compounds, and targeted delivery of pharmaceuticals. Handbook of Drug Screening describes the construction and compilation of chemical compound databases in the fields of genomics, combinatorial chemistry, high-throughput screening, and clinical trials for the use of drug discovery and development! Contains practical applications and examples of recent strategies in cell-based and cell-free screens, as well as homogeneous, fluorescence, chemiluminescence, and radioactive-based technologies�including fluorescence polarization, homogeneous time-resolved fluorescence, fluorescence resonance energy transfer, and scintillation proximity! Detailing future methods of in vitro toxicology and nanolevel selection, the Handbook of Drug Screening covers: • identification of transcriptional factors for drug targeting • affinity-based approaches to screening • expense and sensitivity of automated platforms • the role of proteomics and bioinformatics in target identification • laboratory automation and assay miniaturization in ultrahigh-throughput screening • and more! With contributions from nearly 50 international experts, the Handbook of Drug Screening is an up-to-date guide for organic, medicinal, and pharmaceutical chemists and biochemists; agricultural, molecular, and cell biologists; physiologists; chemical engineers; spectroscopists; screening and automation technologists; and graduate-level students in these disciplines. Contents 1. Moving Into the Third Millennium After a Century of Screening 2. Basic Considerations in Designing High-Throughput Screening Assays 3. Screening Platforms 4. Homogenous Assays for High-Throughput and Ultrahigh-Throughput Screening 5. Microbe-Based Screening Systems 6. Molecular Genetic Screen Design for Agricultural and Pharmaceutical Product Discovery 7. Receptor Screens for Small Molecule Agonist and Antagonist Discovery 8. Functional Assay Screens 9. Enzyme Screens 10. Screening Strategies for Ion Channel Targets 11. High-Throughput Screening Assays for Detection of Transcription 12. Screening of Combinatorial Biology Libraries for Natural Products Discovery 13. Higher-Throughput Screening Assays With Human Hepatocytes for Hepatotoxicity, Metabolic Stability, and Drug�Drug Interaction Potential 14. High-Throughput Screening for Metabolism-Based Drug�Drug Interactions 15. The ATCG of Drug Discovery 16. Genomics/Functional Proteomics for Identification of New Target 17. Bioinformatics: Identification of Novel Targets and Their Characterization 18. The Evolution of Laboratory Automation 19. Robotics and Automation 20. Assay Miniaturization: Developing Technologies and Assay Formats 21. Screening in the NanoWorld: Single-Molecule Spectroscopy and Miniaturized High-Throughput Screening Link: http://rapidshare.de/files/33100666/HoDS.rar |
回复此楼» 猜你喜欢
分享一款实验室长期在用的 TEV 蛋白酶，蛋白纯化党可以参考下
已经有1人回复
-
这些Scopus收录的英文国际期刊正在征稿（快速审稿）2026年底前免APC！
已经有12人回复
-
生物物理、生物化学与分子生物学论文润色/翻译怎么收费?
已经有207人回复
-
做mRNA体外加帽，Cap0转Cap1效率不稳？分享一款2´-O甲基转移酶实测感受
已经有0人回复
-
美国南加大(USC)药学院Prof. Yong (Tiger) Zhang课题组诚聘博士后
已经有3人回复
-
反应产物总提不上量？聊聊无机焦磷酸酶在核酸合成里的实用价值
已经有0人回复
-
【经验分享】体外转录踩坑无数，挖到一款好用的国产 T7 RNA 聚合酶
已经有0人回复
-
体外转录 / PCR 总提不上产量？终于找到稳定好用的无机焦磷酸酶
已经有5人回复
-
[会议预告]2026生物医药产业发展大会
已经有0人回复
1
 |
2楼2006-09-15 12:44:25
mappleleave
木虫 (著名写手)
- 应助: 2 (幼儿园)
- 金币: 8519.9
- 红花: 2
- 帖子: 1672
- 在线: 526.7小时
- 虫号: 212300
- 注册: 2006-03-08
- 专业: 有机合成
3楼2006-09-15 13:09:15
1
 |
4楼2006-09-15 13:57:21
5楼2006-09-23 12:00:04
dnazyme
捐助贵宾 (知名作家)
老虫
- 应助: 28 (小学生)
- 贵宾: 0.1
- 金币: 1942.7
- 散金: 378
- 红花: 13
- 帖子: 6097
- 在线: 2056.5小时
- 虫号: 35203
- 注册: 2004-02-01
- 性别: GG
- 专业: 系统生物学
6楼2006-09-23 21:27:41
0.25
 |
7楼2006-09-24 08:02:16
8楼2006-10-25 13:18:55
0.5
 |
9楼2006-11-17 10:40:47
10楼2006-11-18 20:28:10
