24小时热门版块排行榜

返回列表

本帖产生 1 个翻译EPI ，点击这里进行查看

974790421

新虫 (初入文坛)

应助: 0 (幼儿园)
金币: 430.8
帖子: 37
在线: 12小时
虫号: 1009181

[交流] 求助翻译一段文字

改性β-环糊精（β-CD）与模型底物分子的配位作用一般相对较弱，即使在其边臂上引入某种功能基的简单修饰也很难显著提高其分子键合能力，这在很大程度上限制了环糊精在模拟酶和识别底物等方面的应用。但如果将两个环糊精单元通过适当的基团连接起来，可以得到具有双重疏水结合作用和多重识别功能的桥连双环糊精，由于结合位点的增加，以及可以通过调节连接基团以达到适宜的几何匹配，两个相邻的环糊精空腔可协同参与对形状和尺寸适合的客体分子进行包结，扩展分子键合能力，给出更高的配位稳定常数，这种特性使其有可能在酶．底物和抗原．抗体强键合相互作用模拟研究中得到重要应用。

回复此楼

» 猜你喜欢

» 抢金币啦！回帖就可以得到:

查看全部散金贴

1楼 2011-03-28 14:15:38

已阅回复此楼关注TA 给TA发消息送TA红花 TA的回帖

娇娇jiaojiao

木虫 (著名写手)

翻译EPI: 4
应助: 5 (幼儿园)
金币: 1517.7
帖子: 1738
在线: 205.6小时
虫号: 1206282

974790421(金币+10, 翻译EPI+1): 2011-03-28 17:11:00

Modified beta cyclodextrins (beta CD) substrate molecule with model the coordination effect of general relatively weak, even in its edge arm, introducing some function is difficult to significantly improve the simple modified its molecular bonding ability, this is largely limiting cyclodextrins in simulation of enzyme and identify the application of substrate, etc. But if the two cyclodextrins unit through proper groups.important up, can get with dual scanty water binding and multiple identification function of the bridge, because even 2-ring dextrin binding sites, and can increase by adjusting the connection to achieve appropriate geometry groups in the match, the two adjacent cyclodextrins cavity can collaborative participation on the shape and size of the object for molecule bag knot, expand molecular bonding ability, give higher the coordination stable constants, this characteristic that might in the substrates and antigen enzyme. Strong bonding. Antibodies interaction get important application simulation study.

赞一下