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【答案】应助回帖
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sltmac(金币+30): 2011-04-25 12:50:40
sltmac(金币+30, 翻译EPI+1): 欢迎常来~~ 2011-04-25 12:50:49
Jin Huangyi particles of primary bile duct stones after the impact of plasma levels of gastrointestinal hormones
Primary biliary duct stones are a common and frequently-occurring disease, the current effects of Western medicine treatment of bile duct stones is still not satisfied with the performance of the stone after stone after surgery, residual stone rate, relapse rate and higher rate of re-operation, Western RONGSHI effect is not satisfactory, and the indication is restricted, toxic side effects as well. Therefore, the development of Chinese medicine with modern new achievements in the formation of bile duct causes and prevention of stone recurrence after surgery, the subject of attention in recent years.
Objective
In recent years, people on the causes of bile duct stones and found that the gastrointestinal tract, biliary motility disorders actor in the important role of bile duct stones, gastrointestinal tract, biliary dynamic regulation by gastrointestinal hormones, gastrointestinal hormones in one or changes to a number of important hormones, can lead to gastrointestinal tract, biliary disorders, abnormal secretion of bile, bile stone formation can occur, leading to precipitation of biliary sludge, gallstone formation. With the development of modern Chinese medicine, traditional Chinese medicine have found that some of the role of regulating gastrointestinal hormones. Under this inspiration, to patients with primary common bile duct stones after taking Jin Huangyi bile particles detected by radioimmunoassay method (radioimmunoassay, RIA) measurement of plasma motilin, somatostatin, P material level, to explore Jin Huangyi primary bile duct stones particles on stone recurrence after surgery prevention mechanism.
Materials and methods
First, material
(A) of the main instruments and equipment: SHINKO a SH a 210R electronic balance; GC-2016r RIA counter; LDR4-8.4C Centrifuge; SANYO ultra-low temperature freezer for a 70 ℃.
(B) of the main reagents: suppression skin enzyme (40 000 kiu / ML, 2ML / bottle); 7.5% EDTA a 2Na (2ML / bottle); motilin radioimmunoassay kit;. P substance radioimmunoassay kit.
Second, the experimental method
(A) of the study
Kailuan case samples mainly hospital in May 2008 - May 2009 between the primary or recurrent hospitalization in patients with 66 cases of bile duct stones; normal healthy control group for the families of 10 health care workers and patients. These subjects were not taking near-term impact of the gastrointestinal tract, biliary power of the drug. Bile duct stones after hospitalization, according to stone location, select the appropriate surgical approach, surgery in all patients with biliary stone mirror. In these records are excluded in both patients with gallbladder stones, acute obstructive suppurative cholangitis in patients with abdominal combined with other gastrointestinal diseases, diabetes, fatty liver, cirrhosis, hepatitis B and patients with hyperlipidemia, can not tolerate the drug allergy in patients with simple biliary-enteric anastomosis in patients with pregnancy or for pregnant women and lactating women. All patients were randomly divided into: drug group (taking Jinhuang Yi bile particle group), the control group (natural recovery group), normal group (normal healthy), age and sex of each group comparison table below |
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