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| The consequences are that the D-T interaction data currently available from public repositories are largely incomplete and the portion accessible is often nonhomogeneous and biased toward targets of common therapeutic interest. Therefore, conclusions derived from early topological analyses performed on D-T networks obtained from largely incomplete data should be taken with caution. |
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★ ★ ★ ★ ★ ★ ★
hustandwhu(金币+1, 翻译EPI+1): 2011-03-08 08:15:42
ringzhu(金币+7): ~~ 2011-03-16 12:02:11
hustandwhu(金币+1, 翻译EPI+1): 2011-03-08 08:15:42
ringzhu(金币+7): ~~ 2011-03-16 12:02:11
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The consequences are that the D-T interaction data currently available from public repositories are largely incomplete and the portion accessible is often nonhomogeneous and biased toward targets of common therapeutic interest. Therefore, conclusions derived from early topological analyses performed on D-T networks obtained from largely incomplete data should be taken with caution. 由此导致的结果就是:现在可从公众资源获取的药物-靶点相互作用数据大多数情况下并不完整,而且可获得的资料不具有同质性,更偏重于于常见治疗药物的靶点。因此基于大量不完整数据所进行的早期药物-靶点网络拓扑分析所得出的结论在采用时应相当谨慎。 |
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