| ²é¿´: 272 | »Ø¸´: 3 | |||
| ±¾Ìû²úÉú 1 ¸ö ·ÒëEPI £¬µã»÷ÕâÀï½øÐв鿴 | |||
[½»Á÷]
·ÒëÒ»¾ä»°
|
|||
|
Campillos et al. (2008) was the use of similarities in the sideeffects of known drugs to predict new drug-target interactions, some of which were verified by in vitro binding assays. The limitation of this approach is that it only applies to known side-effects of known drugs, thus limiting the ability of the method to perform high-throughput screening of potential interactions between new molecules and proteins. |
» ²ÂÄãϲ»¶
368»¯Ñ§Çóµ÷¼Á
ÒѾÓÐ13È˻ظ´
286Çóµ÷¼Á
ÒѾÓÐ4È˻ظ´
0703»¯Ñ§Çóµ÷¼Á
ÒѾÓÐ12È˻ظ´
µ÷¼Á
ÒѾÓÐ3È˻ظ´
²ÄÁϵ÷¼Á
ÒѾÓÐ13È˻ظ´
285Çóµ÷¼Á
ÒѾÓÐ18È˻ظ´
»úе¹¤³Ì313·ÖÕÒ¹¤¿Æµ÷¼Á
ÒѾÓÐ3È˻ظ´
¿¼Ñе÷¼Á-²ÄÁÏÀà-284
ÒѾÓÐ9È˻ظ´
Ò»Ö¾Ô¸ÏôóÉúÎïѧ332Çóµ÷¼Á
ÒѾÓÐ3È˻ظ´
±¾¿Æ211£¬293·ÖÇëÇóµ÷¼Á
ÒѾÓÐ13È˻ظ´
» ÇÀ½ð±ÒÀ²£¡»ØÌû¾Í¿ÉÒԵõ½:
Ë®¿ÆÔºÄϺ£ËùÓëÉϺ£º£Ñó´óѧÁªºÏÅàÑøÑо¿Éú2026µ÷¼Á
+1/490
½Î÷¿Æ¼¼Ê¦·¶´óѧ ²ÄÁÏÓëÄÜÔ´ÕÐÊÕµ÷¼ÁÑо¿Éú
+1/85
±±·½Ãñ×å´óѧ085602»¯Ñ§¹¤³ÌÓе÷¼ÁÃû¶î58¸ö£¬»¶Óµ÷¼Á£¡4ÔÂ11ÈÕ±¨µ½£¬12ÈÕÏÖ³¡¸´ÊÔ
+1/45
Ìì½òÀí¹¤ÉúÃü½¡¿µÖÇÄܼì²âÑо¿Ôº2026Äêµ÷¼ÁÉú
+1/40
ɽÎ÷´óͬ´óѧÎïÀíѧÕÐÊÕµ÷¼ÁÉú£¡
+1/39
¿ÆÑÐСÖúÀíÕÐÆ¸~~~¿ª¹¤À²
+1/39
»ªÄÏÀí¹¤´óѧ »ù´¡Ò½Ñ§Ñ§Ë¶ºÍÁÙ´²Ò½Ñ§Ñ§Ë¶µ÷¼Á
+1/20
Î人¹¤³Ì´óѧ»¯Ñ§Óë»·¾³¹¤³ÌѧԺ2026Äê˶ʿÑо¿Éúµ÷¼Á¹«¸æ
+1/13
̫ԿƼ¼´óѧ¹âѧ¹¤³Ìѧ¿Æ½ÓÊܵ÷¼Á
+1/12
×öÁ÷ÌåʵÑ黹ÔÚ´ÕÉ豸£¿ÕâÌ׸߾«ÃÜÁ÷³¡¿ÉÊÓ»¯·½°¸ÕæµÄÊʺϸßУÂð£¿
+1/12
ÉÂÎ÷¿Æ¼¼´óѧÇṤ¿ÆÑ§Ó빤³ÌѧԺÁõÀÏʦ½ÓÊÕ08רҵÑо¿Éúµ÷¼Á
+1/10
¡ïÉϺ£¡ïÉϺ£¹¤³Ì¼¼Êõ´óѧ¡¤»·¾³Óë×ÊÔ´´´ÐÂÖÐÐÄ£¨ICER£©½ÓÊÕ»¯¹¤²ÄÁÏ»·¾³µÈѧ¿Æµ÷¼ÁÉú
+1/8
ÖйúµØÕð¾ÖµØÖÊÑо¿Ëù+µØÑ§/ÊýѧÏà¹Ø×¨Òµ+½ÓÊÕµ÷¼Á
+1/7
Æë³¹¤Òµ´óѧ ¹ú¼ÒÖØµãʵÑéÊÒ-ÐÂÄÜÔ´¡¢ï®Àë×Óµç³Ø¡¢²ÄÁÏ¡¢»¯Ñ§·½Ïò
+1/5
¹óÖݲƾ´óѧÐÂÒ»´úµç×ÓÐÅÏ¢¼¼Êõ£¨º¬Á¿×Ó¼¼ÊõµÈ£©Ë¶Ê¿×¨Òµ£¨085401£©½ÓÊÕµ÷¼Á
+1/5
×Ü·Ö338Çóµ÷¼Á£¬±¾¿Æ´óÁ¬Àí¹¤Ò»Ö¾Ô¸±±º½ÉúÒ½¹¤083100
+1/4
´óÁ¬¹¤Òµ´óѧ·ÄÖ¯Óë²ÄÁϹ¤³ÌѧԺ³¬ÁÙ½çÁ÷Ìå¼¼Êõ¿ÎÌâ×é Ñо¿Éúµ÷¼Á
+1/4
º«¹úººÑô´óѧÊ×¶ûÐ£ÇøADIP ʵÑéÊÒ³ÏÕв©Ê¿ºó£¨²»ÏÞרҵ£¬´ýÓöÓźñ£¬Æ½Ì¨×ÊÔ´·á¸»£©
+1/3
ÉúÎï»ù£¨¾úÎ²ÄÁÏ¿ÎÌâ×顪¡ªµ÷¼ÁÕÐÉú2026
+1/1
¼ÃÄÏ´óѧ2026Äê˶ʿÑо¿ÉúÕÐÉúÔ¤µ÷¼Á¹«¸æ
+1/1
8814402
ÖÁ×ðľ³æ (Ö°Òµ×÷¼Ò)
- ·ÒëEPI: 509
- Ó¦Öú: 18 (СѧÉú)
- ¹ó±ö: 0.381
- ½ð±Ò: 12916.1
- Ìû×Ó: 4183
- ÔÚÏß: 357.8Сʱ
- ³æºÅ: 1184404
¡ï ¡ï ¡ï ¡ï ¡ï ¡ï ¡ï ¡ï ¡ï ¡ï ¡ï ¡ï ¡ï ¡ï ¡ï ¡ï
pku123(½ð±Ò+1, ·ÒëEPI+1): 2011-03-04 09:37:38
pku123(½ð±Ò+1): 2011-03-05 07:32:19
ringzhu(½ð±Ò+16): ²»½âÊÍ~~ 2011-03-15 10:23:03
pku123(½ð±Ò+1, ·ÒëEPI+1): 2011-03-04 09:37:38
pku123(½ð±Ò+1): 2011-03-05 07:32:19
ringzhu(½ð±Ò+16): ²»½âÊÍ~~ 2011-03-15 10:23:03
|
Campillos et al. (2008) was the use of similarities in the side effects of known drugs to predict new drug-target interactions, some of which were verified by in vitro binding assays. The limitation of this approach is that it only applies to known side-effects of known drugs, thus limiting the ability of the method to perform high-throughput screening of potential interactions between new molecules and proteins. Campillos µÈ(2008)ÓÃÒ»Ö»Ò©ÎïµÄ¸±×÷ÓõÄÏàËÆÐÔÔ¤²âÐÂÒ©ºÍ°Ð±ê¼äµÄÏ໥×÷Óã¬ÆäÖÐһЩÏ໥×÷ÓÃÓÉÌåÄÚ½áºÏʹÓÃÈ·Ö¤¡£ÕâÖÖ·½·¨µÄ¾ÖÏÞÊÇËüÖ»Ó¦ÓÃÁËÒÑÖªÒ©ÎïµÄÒÑÖª¸±×÷Óã¬Òò´ËÏÞÖÆÁËÆäÔÚзÖ×Ӻ͵°°×ÖÊÖ®¼äDZÔÚÏ໥×÷ÓõĸßͨÁ¿É¸Ñ¡ÖеÄÓ¦Óᣠ|
2Â¥2011-03-04 09:37:04
8814402
ÖÁ×ðľ³æ (Ö°Òµ×÷¼Ò)
- ·ÒëEPI: 509
- Ó¦Öú: 18 (СѧÉú)
- ¹ó±ö: 0.381
- ½ð±Ò: 12916.1
- Ìû×Ó: 4183
- ÔÚÏß: 357.8Сʱ
- ³æºÅ: 1184404
3Â¥2011-03-04 09:38:04
8814402
ÖÁ×ðľ³æ (Ö°Òµ×÷¼Ò)
- ·ÒëEPI: 509
- Ó¦Öú: 18 (СѧÉú)
- ¹ó±ö: 0.381
- ½ð±Ò: 12916.1
- Ìû×Ó: 4183
- ÔÚÏß: 357.8Сʱ
- ³æºÅ: 1184404
4Â¥2011-03-04 11:12:58














»Ø¸´´ËÂ¥