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The robustness of these NIP and MIP materials is demonstrated by the fact that over an 8-month period, similar responses towards both NIP and MIP materials was observed following the use of a range of solvents on the SPE columns over time. Reproducibility of extraction observed when two separate SPE cartridges were packed in parallel is also illustrated in Figs. 5 and 6. Similarly the small error bars evident in Figs. 5, 6 and 8 illustrate the reproducibility of response of each SPE cartridge to repeat loadings. This research was funded under the Technological Sector Research and Initiative (2001) (Strand III) supported by Merck, Sharpe & Dohme, Clonmel Ltd., Ireland. The help of Sharon Marx, Department of Physical Chemistry, Israel Institute for Biological Research, Ness-Ziona, 70450 Israel, in the initial stages of this work is also greatly appreciated. |
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