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The 22nd Edition of the Cecil Textbook of Medicine symbolizes a time of extraordinary advances in medicine and in the methods for the dissemination of information. This hardbound, published textbook and its associated electronic products incorporate the latest medical knowledge in formats that are designed to be appealing to physicians who prefer to access information in a variety of ways.

The contents of Cecil have remained true to the tradition of a comprehensive textbook of medicine that carefully explains the why (the underlying normal physiology and pathophysiology of disease, now at the cellular and molecular as well as the organ level) and the how (now frequently based on Grade A evidence from randomized controlled trials). Descriptions of physiology and pathophysiology include the latest genetic advances in a practical format that strives to be useful to the non-expert. Grade A evidence is now specifically highlighted in the text and referenced at the end of each chapter. The electronic version provides an immediate link to the cited reference and will be continuously updated to incorporate subsequent Grade A information.

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