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Doctorcbw木虫 (职业作家)
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把下面一段文字 翻译成汉语！谢谢大家！急呀
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University of New South Wales ADFA Faculty Canberra Australia PhD Project Modeling Protein Aggregation: From Alzheimer’s Disease and Nanoparticles to Food Processing Interactions between proteins cause much of the diverse phenomena in biology. They determine how life works and when it goes wrong. The so-called amyloid diseases, such as Alzheimer’s and type II diabetes mellitus, are associated with the aggregation of slightly misfolded proteins into amyloid fibrils (needle-like fibers). It has now been established, that such structures can also be formed by proteins not implicated in the amyloid diseases. This suggests a common structural motif is responsible and that this can be potentially uncovered through appropriate modeling of protein interactions. External factors may also have a profound affect on the way proteins aggregate and recent experiments (by one of our collaborators) have shown that the presence of nanoparticles can promote fibril nucleation, but the mechanism remains unknown. Protein interactions are also important in technologies such as food processing. An important example are whey proteins, which remain as a dilute mixture in cow milk after cheese production. The large-scale post-processing of whey, to extract valuable protein components, is still in its infancy and more efficient routes to achieving targeted separation would revolutionize that industry. Thus the wide-ranging importance of protein interactions and aggregation has created a lot of interest in this field for both experimentalists and theoreticians. In this project, we will develop novel models for protein interactions and use them to study important protein aggregation problems of the type described above. This project is part of a larger collaboration between researchers from UNSW@ADFA, Sweden and the USA. Applicants with a background in Mathematics and Physical Chemistry, Physics or Engineering are encouraged to apply. Enquiries to: Associate Professor Cliff Woodward, School of Physical, Environmental and Mathematical Sciences, University of New South Wales at the Australian Defence Force Academy, ACT 2600. Email: c.woodward@adfa.edu.au 这一段翻译成汉语！谢谢大家！ |
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2楼2010-08-30 12:13:44
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Doctorcbw(金币+45):谢谢 2010-08-30 13:29:38
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新南威尔士大学 ADFA学院 澳大利亚堪培拉 博士项目 蛋白质聚集模型：从阿尔茨海默氏病和纳米粒子到食品加工 蛋白质间的相互作用造成了各种生物现象。他们决定生命如何延续以及何时出错。所谓的淀粉样疾病，如老年痴呆症和II型糖尿病，与折叠略有错误的蛋白质聚集成淀粉样纤维（针状纤维）有关。现在已经证实，这种结构也可以由不表达淀粉样疾病的蛋白质组成。这表明了共同的结构模体是其原因，可通过蛋白质相互作用的模型被发现。外部因素也可能对蛋白质聚集的方式产生重大影响。近期一个研究（由我们的合作者之一开展的）表明，纳米粒子的存在可能促进纤维成核，但其机制尚不清楚。蛋白质之间的相互作用对于一些技术是很重要的，如食品加工。一个重要的例子是牛奶加工为奶酪之后，乳清蛋白仍然以稀释的混合物形式存在。大规模的乳清后处理来提取有价值的蛋白质成分的技术尚处于起步阶段，实现目标分离更有效的方式将会改革该工业。因此，蛋白质相互作用和聚集的广泛重要性，引起了实验家和理论家对这一领域的浓厚兴趣。 在这个项目中，我们将开发新的蛋白质相互作用的模型，并利用它们来研究上述类型的重要的蛋白质聚集问题。 该项目是新南威尔士大学@ ADFA，瑞典和美国的研究人员之间大规模合作项目的一部分。 欢迎有数学和物理化学，物理或工程背景的人员踊跃申请。请咨询：澳大利亚国防军学院的ACT 2600新南威尔士大学，物理、环境和数学科学学院，克利夫伍德沃德副教授 电子邮件：c.woodward @ adfa.edu.au |
3楼2010-08-30 13:07:16
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