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momo_458(金币+12, 翻译EPI+1): 2010-08-28 09:57:00
Diabetes, the renin - angiotensin system (renin-angiotensin system, RAS) is activated, elevated angiotensin Ⅱ (Ang Ⅱ) AT1 receptor by cell surface and stimulate cardiac fibroblast proliferation and collagen metabolism changes cardiac remodeling, resulting in myocardial interstitial and perivascular fibrosis, and disordered collagen content increased, resulting in ventricular stiffness affect diastolic function, heart disease to diabetes (diabetic cardiomyopathy, DCM) of the clinical symptoms. In this paper, the main component of RAS Ang Ⅱ, Ang-(1-7), Ac-SDKP and Angiotensin Receptor (ATR) and expounds the RAS in the development of diabetic cardiomyopathy played an important role.
This article comes from: wooden insect Forum https://muchong.com/bbs/viewthread.php?tid=2329874&fpage=2 |
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