|
|
★
wypward(金币+1):谢谢参与 2010-06-11 20:06:50
xiaolu0424(金币+30, 翻译EPI+1): 2010-06-12 09:02:43
|
Lamiophlomis rotata Kudo，a traditional Tibetan medicine, its pharmaceutical preparation is mainly used for treating pain and bleeding after a variety of surgical incisions, trauma fractures, bones, muscles hurt, rheumatism and paralysis, uterine bleeding, dysmenorrhea, gingival swelling, as well as bleeding. (Pharmacopoeia 2005 Edition). Previously, luteolin was used as an index in the quality control of Kudo medicinal materials and preparations, however, luteolin is of low specificity. The existing data indicates that the effective components of Kudo for haemostasis is iridoid terpene chemicals, while 8-O-acetyl ester Hill methylester is a compound of this series with higher levels of content, also with strong specificity. Just for this reason, Hill 8-O-acetyl ester methylester has been selected as an indicator of quality control in Pharmacopoeia 2010 Edition. In order to demonstrate legitimacy of this method and provide a reference for clinical medication, its pre-clinical pharmacokinetic study was carried out in this thesis. |
|
回复此楼