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小木虫论坛-学术科研互动平台 » 学术交流区 » 论文投稿 » 投稿求助 » 求助：大修
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pphss

至尊木虫 (著名写手)

[交流] 求助：大修 已有3人参与

Reviewer #1: 1.     Introduction.  Why do the authors choose a rabbit model?  What are the advantages of this animal?  Why not a larger animal model, such as a dog or sheep?
2.     Methods.  What kind of rabbit was used?  What diet was it fed on (normal or high cholesterol)?
3.     Methods.  Did the authors excise a piece of the carotid artery?  How long a graft was used?  What was its diameter?  What sutures were used to suture the vein graft?
4.     Results, Figure 1.  What was the time until 50% of the drug was eluted?  It appears to be approximately 21-28d in Figure 1F, but an exact calculation would be useful.
5.     Results, Figure 2.  This figure would be more convincing if Panels B and C were aligned in the same direction, and a scale bar was given (showing panels B and C to be higher magnification).
6.     Results, Figure 2.  How was the intimal thickness calculated?  Manually at several spots, or with computer-aided morphometry?  Was the thickness based off of an elastin stain for accuracy?
7.     Results, Figure 3.  The authors use immunohistochemistry as an exclusive method of detection.  Did the authors confirm their findings with a Western blot?
8.     Do the authors believe that rapamycin will be clinically useful for human patients?
9.     Does rapamycin suppress the rabbit immune system?  Did the authors measure immune system function?
10.     Did the authors measure systemic rapamycin levels in the serum?
11.     Did the authors give oral rapamycin to confirm their findings?


是只要回答问题，还是要加做实验？
还有什么好的意见和建议，请不吝赐教。
多谢！多谢！
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1楼 2010-05-25 07:32:48
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zhiyongwang

至尊木虫 (文坛精英)
那就照意见好好修改，祝福好运
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4楼2010-05-25 10:47:00
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很爱很爱你

铁杆木虫 (著名写手)
★
小木虫(金币+0.5):给个红包，谢谢回帖交流
不仅要加实验，而且要回答问题
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2楼2010-05-25 08:47:38
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pphss

至尊木虫 (著名写手)
引用回帖:
Originally posted by 很爱很爱你 at 2010-05-25 08:47:38:
不仅要加实验，而且要回答问题

加实验不可能了，没时间精力了。
仅回答回答问题，能中吗？
编辑部叫我6w内回复他们。要是做实验，肯定不可能。他们应该会想到。是不是他们也认为只要回答回答问题就行了？但是退修意见是很明确的大修！

[ Last edited by pphss on 2010-5-25 at 09:28 ]
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3楼2010-05-25 09:24:45
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pphss

至尊木虫 (著名写手)
引用回帖:
Originally posted by zhiyongwang at 2010-05-25 10:47:00:
那就照意见好好修改，祝福好运

多谢，多谢
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5楼2010-05-25 10:54:55
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