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houjiting

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【作者(必填)】 Takeshi Kono , a,  , Tsukasa Taniia, Masayoshi Furukawaa, Nobuyuki Mizunoa, Shoji Taniguc
【文题(必填)】 《Effect of tretinoin on collagen gel contraction induced by mouse 3T3 fibroblasts 》
【期刊名,年份,卷(期),起止页码(必填)】 Journal of Dermatological Science  Volume 2, Issue 1, January 1991, Pages 45-49
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hsf81105

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houjiting(金币+15, 博学EPI+1):谢谢你~ 2010-04-12 15:05
3楼2010-04-11 02:46:04
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luoxianyang

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不好意思,只能找到摘要。不过你可以看这篇文章的作者发的其他文章,找到他的邮箱或者联系方式,发邮件索要这篇文章。抱歉
Abstract - selected   
  Journal of Dermatological Science
Volume 2, Issue 1, January 1991, Pages 45-49
--------------------------------------------------------------------------------
doi:10.1016/0923-1811(91)90041-U | How to Cite or Link Using DOI
Copyright © 1991 Published by Elsevier Ireland Ltd.    Cited By in Scopus (1)  
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Regular paper
Effect of tretinoin on collagen gel contraction induced by mouse 3T3 fibroblasts

This article is not included in your organization's subscription. However, you may be able to access this article under your organization's agreement with Elsevier.

Takeshi Kono, a, , Tsukasa Taniia, Masayoshi Furukawaa, Nobuyuki Mizunoa, Shoji Taniguchia, Masamitsu Ishiia, Toshio Hamadaa and Katsutoshi Yoshizatob

a Department of Dermatology, Osaka City University Medical School, Abeno-ku, Osaka, Japan

b Developmental Biology Laboratory, Zoological Institute, Faculty of Science, Hiroshima University, Naka-ku, Hiroshima, Japan

Received 6 December 1989;  accepted 25 July 1990.  Available online 21 April 2005.

Abstract
Balb/3T3 fibroblasts were cultured in type I collagen gel and the effects of tretinoin (all-trans-retinoic acid) were examined on cell growth and the gel contraction produced by cells. Cell proliferation was suppressed and the degree of gel contraction was enhanced by the addition of 10−7 and 10−6 M tretinoin. Growth and gel contractility of transformed cells derived from the Balb/3T3 cells were not influenced by this agent. Addition of 12-O-tetradecanoylphorbol ester, which is known to antagonize tretinoin in several biological processes, enhanced gel contraction synergistically with tretinoin. These results suggest that tretinoin influences cell-to-collagen interactions.

Author Keywords: Collagen gel culture; Collagen, type I; Balb/3T3 cells; Cell growth; Tretinoin (all-trans-retinoic acid); 12-O-Tetradecanoylphorbol-13-acetate (TPA)

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