| 查看: 310 | 回复: 6 | |||
| 当前主题已经存档。 | |||
| 本帖产生 1 个 博学EPI ,点击这里进行查看 | |||
[交流]
求一种纳米颗粒制作方法得资料(很急)
|
|||
|
求关于制作 Poly-(butyl cyanoacrylate) 的文献,中英文都可以,最好有制作流程,因为没办法用数据库,所以只能发在这里了。 还请多多帮忙! [ Last edited by zzgyb on 2010-5-18 at 12:43 ] |
» 猜你喜欢
281求调剂(0805)
已经有8人回复
环境领域全国重点实验室招收博士1-2名
已经有3人回复
材料专硕306英一数二
已经有10人回复
301求调剂
已经有6人回复
一志愿天津大学化学工艺专业(081702)315分求调剂
已经有7人回复
302求调剂
已经有6人回复
26博士申请
已经有3人回复
268求调剂
已经有3人回复
311求调剂
已经有10人回复
被我言中:新模板不强调格式了,假专家开始管格式了
已经有4人回复
haiyanshd
木虫 (著名写手)
- 博学EPI: 2
- 应助: 0 (幼儿园)
- 金币: 2514.3
- 散金: 68
- 帖子: 1121
- 在线: 124.7小时
- 虫号: 759107
- 注册: 2009-04-28
2楼2010-03-15 08:55:03
hych(金币+10, 博学EPI+1): 2010-04-13 18:04
|
Toxicological studies of doxorubicin bound to polysorbate 80-coated poly(butyl cyanoacrylate) nanoparticles in healthy rats and rats with intracranial glioblastoma Toxicology Letters 126 (2002) 131–141 Nanoparticle-bound doxorubicin (DOX–NP) was prepared by anionic polymerisation (Gulyaev et al., 1999). Briefly, 1% of butylcyanoacrylate was added to 1% dextran solution in 0.001 N HCl under constant stirring. After 40 min DOX was added to the mixture to obtain a final concentra- tion 0.4%. After 2.5 h the mixture was neutralised, filtered and freeze-dried with addition of 3% man- nitol as cryoprotector. The particle size was mea- sured by light scattering (Nanosizer Malvern, Great Britain), an average diameter of 27030 nm was found. The amount of free drug in the preparation was assessed spectrophotometrically after particle separation by centrifugation. It wasshown that 80% of the drug in suspension was associated with the NP. For surfactant coating 1% polysorbate 80 was added to the suspension, and the suspension was incubated for 30 min under stirring and then used within 2 h. Empty NP (average diameter of 25030 nm) were pro- duced using the same technique. 一篇文献上的,不知有用没? |
3楼2010-03-15 11:22:20
haiyanshd
木虫 (著名写手)
- 博学EPI: 2
- 应助: 0 (幼儿园)
- 金币: 2514.3
- 散金: 68
- 帖子: 1121
- 在线: 124.7小时
- 虫号: 759107
- 注册: 2009-04-28
4楼2010-03-15 13:42:24
5楼2010-03-15 16:48:26
haiyanshd
木虫 (著名写手)
- 博学EPI: 2
- 应助: 0 (幼儿园)
- 金币: 2514.3
- 散金: 68
- 帖子: 1121
- 在线: 124.7小时
- 虫号: 759107
- 注册: 2009-04-28
6楼2010-04-04 15:20:52
haiyanshd
木虫 (著名写手)
- 博学EPI: 2
- 应助: 0 (幼儿园)
- 金币: 2514.3
- 散金: 68
- 帖子: 1121
- 在线: 124.7小时
- 虫号: 759107
- 注册: 2009-04-28
7楼2010-04-04 15:23:22













回复此楼