| 查看: 328 | 回复: 5 | |||
| 当前主题已经存档。 | |||
| 【悬赏金币】回答本帖问题，作者000zgh000将赠送您 9 个金币 ，回答问题就立即获得 1 个金币，每人有 1 次机会 | |||
| 当前只显示满足指定条件的回帖，点击这里查看本话题的所有回帖 | |||
[求助]
修改一段中译英（急急急）
|
|||
|
安全、有效、具有靶向性的病毒载体是基因治疗药物在临床上得以应用的关键。microRNA是一类单链、内源性的转录后调控小分子，它的发现为开发具有靶向性调控能力的病毒载体提供了新的研究方向。以下在介绍microRNA调节病毒载体靶向性原理的基础上，着重介绍microRNA在清除复制能力病毒的污染、消除转基因特异性免疫、增强肿瘤靶向性基因治疗、开发活体疫苗等领域的应用。 Safe, effective and targeting viral vector is the key factor for successful clinical gene therapy. microRNA, a class of small, single-stranded endogenous RNAs, act as post-transcriptional regulators of gene expression.The discovery of this kind regulatory elements provide a new field for targeting regulation in gene therapy. Here, we elucidated the principle of microRNA in regulation of targeting viral vector. Then, the applications of microRNA in the fields of elimination contamination from replication competent virus, reduction of transgene-specific immunity, promotion of cancer-targeted gene therapy and development of live attenuated vaccines were further discussed. |
回复此楼» 猜你喜欢
求调剂
已经有3人回复
-
一志愿北京化工大学，初试成绩350求调剂
已经有14人回复
-
复试调剂
已经有4人回复
-
323分（计算机视觉和大模型项目）能直接上手
已经有3人回复
-
311分 22408 求调剂
已经有3人回复
-
320分人工智能调剂
已经有7人回复
-
一志愿郑大0705求调剂
已经有4人回复
-
0703化学
已经有10人回复
-
301求调剂
已经有10人回复
-
306分材料与化工求调剂
已经有6人回复
★
000zgh000(金币+1):谢谢参与
000zgh000(金币+1):感谢您的支持 2010-03-04 21:38
000zgh000(金币+1):谢谢参与
000zgh000(金币+1):感谢您的支持 2010-03-04 21:38
| Safe, effective and targeting viral vector is the key to successful application of clinical gene therapy. The discovery of microRNA has blazed a trail for targeting regulation in gene therapy. microRNA is a class of small, single-stranded endogenous RNAs and act as post-transcriptional regulators of gene expression. At the present study, the emphases are placed on the applications of microRNA in the fields of elimination contamination from replication competent virus, reduction of transgene-specific immunity, promotion of cancer-targeted gene therapy and development of live attenuated vaccines based on the principle of microRNA in regulation of targeting viral vector. |
3楼2010-03-04 20:20:28
2楼2010-03-04 19:42:08
4楼2010-03-04 20:22:46
5楼2010-03-04 21:39:26
