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huhuiowen荣誉版主 (著名写手)
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【迎虎年奖励活动——博士后招聘信息发布帖】2010.02.22
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欢迎虫友积极参加，信息发布在本帖！活动规则和奖励细则见： http://muchong.com/bbs/viewthread.php?tid=1828034&fpage=1 活动已经结束，谢谢！ [ Last edited by huhuiowen on 2010-2-28 at 06:07 ] |
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huhuiowen
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1、xxxx 大学（研究所）招聘博士后（必填）美国威斯康星大学公共健康医学院招聘博士后 2、xxxx 专业方向（必填） stem/progenitor cell function, blood cell development, and vascular biology 3、博后位置介绍（必填）、网址链接（选填）、其他（选填）The Bresnick laboratory is recruiting one or two postdoctoral fellows to join our research group at the Wisconsin Institutes For Medical Research (WIMR) in the University of Wisconsin School of Medicine and Public Health in Madison, WI. The WIMR provides a cutting-edge scholarly environment for conducting innovative basic and translational research. We use multidisciplinary approaches to understand important biological processes, including stem/progenitor cell function, blood cell development, and vascular biology. Such approaches include genomics, proteomics, chemical genetics, and computational analysis, as well as traditional molecular, cellular, and biochemical methodologies. In addition to elucidating biological principles, we aim to develop innovative therapeutic strategies based on targeting novel mechanisms. Projects include: (1) Mechanisms of hematopoiesis. Defining such mechanisms has enormous importance, as deviations from hematopoietic programs yield leukemias, lymphomas and other blood disorders. We are analyzing the function and regulation of GATA transcription factors that control hematopoietic stem and progenitor cell function, hematopoiesis, and additional important processes. Transcriptional profiling and chromatin immunoprecipitation studies have identified a large cohort of novel GATA factor target g enes, including genes encoding proteins that bear no obvious similarity to known proteins. Loss-of-function and gain-of-function studies are being conducted in mice, zebrafish, and cultured cells to elucidate new biological pathways, which will provide key insights into mechanisms of development, differentiation, and human disease. (2) Transcriptional control of hemoglobin synthesis. These studies address fundamental mechanistic questions on how chromatin modification/remodeling regulates transcription of endogenous loci and also how hemoglobin synthesis is dysregulated in human hemoglobinopathies. Many questions remain unanswered regarding how dynamic changes in chromatin are orchestrated during development, differentiation, and pathophysiological processes. (3) Linking GATA factor mechanisms to human disease. GATA-1 mutations cause human leukemias, while GATA-2 mutations occur in leukemia as well as coronary artery disease. We discovered a link between GATA-2 function and P arkinson’s disease and also a GATA-1-regulated endogenous suppressor of angiogenesis that functions via a novel mechanism. Studying GATA factors can yield important insights of considerable relevance to human disease. The successful candidate will develop both independent and collaborative experiments in one or more of our focal areas. 4、导师联系人方式（必填）ehbresni@wisc.edu 感谢zyz1981的贡献！ |
6楼2010-02-02 17:12:28
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huhuiowen:谢谢支持，本地是发布信息的！ 2010-02-02 00:05
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2楼2010-02-01 23:10:15
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huhuiowen:谢谢支持，本地是发布信息的！老hou该打！ 2010-02-02 00:05
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3楼2010-02-01 23:28:21
huhuiowen
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1、xxxx 大学（研究所）招聘博士后（必填）凯丝西储大学医学院药理系招聘博士后职位 2、xxxx 专业方向（必填）药理学 3、博后位置介绍（必填）One postdoctoral position is available in the laboratory of Dr. Youwei Zhang at the Department of Pharmacology, Case Western Reserve University, Cleveland, Ohio, USA. Dr. Zhang’s lab is interested in understanding the molecular mechanisms of cell cycle checkpoint and developing therapeutic strategies against human cancers. We are particularly interested in the S phase replication checkpoint. (Molecular Cell, 19, 607-618, 2005; Molecular Cell, 35, 442-453, 2009). The Department has a broad range of research areas from signaling transduction to protein structure. It provides an excellent environment to foster collaborations among laboratories working on different research areas. Self-motivated individuals who have a PhD degree completed within the past three years are encouraged to apply. Strong background in biochemistry and molecular and cellular biology is required. Cleveland is a beautiful city located near Lake Erie, and has four-season weather. It has a great public education system and living here is very affordable. 4、导师联系人方式（必填）yxz169@case.edu 感谢zyz1981的贡献！ |
4楼2010-02-02 17:11:38
