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tanxiaoyun222

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ÎÒµÄһƪÎÄÕÂͶ¸øÁ˹úÍâÒ»ÔÓÖ¾Éç,±à¼­°ÑÎÒµÄÎÄÕÂÏÈǰֻ¸øÁËһλÉó¸åÈË¿´,²¢·µ»Ø¸øÎÒ×÷ÁËÐÞ¸Ä,¿ÉÎÒ¶þ´Îemail¸øËûÃǺó,±à¼­ÓÖÇëÁËһλÉó¸åÈ˶ÔÎҵĸå¼þ½øÐÐÁËÆÀÉó.¸ÃÉó¸åÈËÔڻظ´ÖÐÓÐÈçÏÂÒ»ÒªÇóDiscussion and Study Design: It would have been very valuable to have two types of orthopedic controls, particularly osteoarthritis and fracture. It may be that the proteins differentiating ON from normal, would not differentiate ON from OA and fracture. ÎÒÏÖÔÚÓÉÓÚ¾­·Ñ¼°Ê±¼äµÄÎÊÌâ,û·¨ÔÙ²¹³ä×öʵÑé,Òò´Ë,ÏëºÍÕâλÉó¸åÈËÁªÏµÒ»ÏÂ,°ÑÎÒ²»Äܲ¹³ä×öʵÑéµÄÀíÓɸæËßËû,ÏÈÈ¡µÃËûµÄÁ½â.ÎÒÏëÕâÑù×öµÄºÃ´¦ÊÇ·À»¼ÓÚδȻ,ÒÔÃâÐ޸ĸå¼þµ½ËûÊÖÀïºóÖ±½Ó±»¾Ü.ÒÔÏÂÊÇÎÒ¸ø±à¼­µÄÐÅ,Çë´ó¼Ò°ïæ¿´¿´,ÕâÑùдÊÇ·ñºÏÊÊ,ÓÐûÓÐʲô´íÎó,лл!

Dear ^^^,

After thinking carefully about the comment of the additional reviewer, I have something about his comment to talk about with him. I'm not sure if it is permissive to contact you to inquire about the email address of the additional reviewer. I would be greatly appreciate if you could send it to me.

If it is not permissive for me to contact with the reviewer, can you be kind to transmit the following to him.

His comment:
P2, Conclusion: Correlation does not necessarily imply causation. Detailed studies need to be done with the 7 proteins to determine whether, for example, they differentiate IONFH from osteoarthritis, from bone trauma, etc.
Discussion and Study Design: It would have been very valuable to have two types of orthopedic controls, particularly osteoarthritis and fracture. It may be that the proteins differentiating ON from normal, would not differentiate ON from OA and fracture.

My response:
Due to the following reasons, I am afraid I can't do additional study. In one hand,the cost on proteomic study is very expensive, but we did not receive outside funding in support of our research; In the other hand, I am a student, I will graduate in June 2006,so I don't have much time to do additional study. But I think we will do it later.

Thank you.

Best regards,

Dr. ^^^
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