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中国海洋大学王杨课题组招收有机合成“申请-考核”制博士研究生
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一、导师介绍 王杨，教授，博士生导师。2008年本科毕业于中国农业大学，同年保送至北京大学化学与分子工程学院，2013年在北京大学获得有机化学博士学位（导师：席振峰院士，张文雄教授）。之后获得欧盟“玛丽居里”学者计划，在瑞士洛桑联邦理工学院（epfl）从事博士后研究（导师：jieping zhu教授）。2017年至2019年在加拿大西蒙弗雷泽大学（sfu）从事博士后研究（导师：robert britton教授）。2019年加入中国海洋大学医药学院独立开展研究工作。2020年入选山东省泰山学者青年专家。在有机化学、药物化学领域具有丰富的经验。在国际期刊上发表具有重要影响力的学术论文20余篇。获得授权专利3项。担任org. lett., chem. commun., j. org. chem., chin. chem. lett.等国际期刊审稿人。 研究方向：有机合成、药物合成 已发表论文： 1. Tengfei Xuan, Hongli Zhao, Yichi Zhang, Jinyu Wang, Shuang Yang, Wei Wang, Yang Wang.* J. Am. Chem. Soc. 2026, DOI: 10.1021/jacs.5c1650 2. pengcheng shao, hang cheng, and yang wang.* asymmetric catalytic dual-site functionalization of allyl bromides: construction of diverse heterocyclic frameworks. Chin. J. Chem. 2026, 44, 111. 3. yongxing zhang, xiaochen tian, and yang wang.* asymmetric catalytic [3+3] annulations of unmodified morita-baylis-hillman alcohols to construct diverse heterobicyclic [4.3.0] skeletons. JACS Au, 2025, 5 , 5039. 4. tingting zhang, xiaochen tian, xin shua, honghan lia, yihan lua, yang wang.* indolylmethanols as c4 synthons for the asymmetric synthesis of indole-fused spiro compounds. Chin. J. Chem. 2025, 43, 3483. 5. tengfei xuan, xia wang, yang wang.* asymmetric [3+2] cycloannulation of benzoxazinones for the synthesis of imidazo[5,1‑c]oxazinones. org. lett. 2025, 27, 3134. 6. xin shu, tingting zhang, yongxing zhang, kexin tong, shumin wang, yang wang.* asymmetric construction of enantioenriched spiro gem-diamines via [3+3] annulation of α,β-unsaturated n-sulfonyl ketimines and 3-aminobenzofurans. org. chem. front. 2025, 12, 3643. 7. tengfei xuan, yuan pan, zhenyu shi, yang wang.* organocatalytic asymmetric synthesis of oxazolines from n-acylimines. chin. chem. lett. 2025, 36, 110352. 8. xiaochen tian, tengfei xuan, jingkun gao, xinyu zhang, tao liu, fengbiao luo, ruochen pang, pengcheng shao, yun-fang yang, yang wang.* catalytic enantioselective nitrone cycloadditions enabling collective syntheses of indole alkaloids. Nat. Commun. 2024, 15, 6429. 9. lesong li, tao liu, weiwu ren, yang wang.* catalyst-free and atom-economical [4+3] cycloaddition of azadienes with cyclic azomethine imines for facile synthesis of 1,2,4-triazepines. green synth. catal. 2024, 5, 57. 10. shuting zhang, xinyu zhang, lesong li, zhenyu shi, yang wang.* synthesis of pyridazino[4,5-b]indoles by [3+3] annulation of 2-alkenylindoles and hydrazonyl chlorides. chem. eur. j. 2024, 30, e202400278. 11. lesong li, congyang li, shuting zhang, xuerui wang, peng fu, yang wang.* catalytic asymmetric synthesis of 3,4′-piperidinoyl spirooxindoles via [3+3] annulation of 3‑aminobenzofurans and isatin-derived enals. j. org. chem. 2024, 89, 5170. 12. lesong li, xia wang, yang wang.* construction of spiro[pyrrolidine-azlactone] via [2+3] cycloaddition of alkylidene azlactone with trifluoromethylated imine j. org. chem. 2024, 89, 17824. 13. xinyu zhang, yuan pan, tao liu, yang wang.* synthesis of 4‑aryl-1,3,4-benzotriazepinones from isatoic anhydrides and hydrazonyl chlorides. j. org. chem. 2023, 88, 7504. 14. hao dong, yongxing zhang, xiaochen tian, ruochen pang, weiwu ren, yang wang.* catalyst-free and oxidant-free tandem aza-mannich/cyclization/aromatization of c,n-cyclic azomethine imines with enamides: facile synthesis of 5,6-dihydropyrazolo[5,1-a]isoquinolines. green. chem. 2022, 24, 5508. (cover page) 15. lesong li, tao liu, xiaoli zhang, xiaohan hou, hao dong, xiaoyang li, weiwu ren, yang wang.* catalyst-free and atom-economical 1,3-dipolar cycloaddition of c,n-cyclic azomethine imines: facile synthesis of isoquinoline-fused spirocycles. green synth. catal. 2022, 2, 69. 16. fengbiao luo, hao dong, weiwu ren, yang wang.* organocatalytic asymmetric synthesis of tetrahydroquinolines from ortho-aminophenyl para-quinone methides. org. lett. 2022, 24, 7727. 17. yuan pan, weiwu ren, zhanhao zhang, fengbiao luo, xiaohan hou, xiaoyang li, yun-fang yang, yang wang.* tandem 1,6-addition/cyclopropanation/rearrangement reaction of vinylogous para-quinone methides with 3-chlorooxindoles: construction of vicinal quaternary carbon centers. org. chem. front. 2022, 9, 3697. 18. xiaochen tian, yongxing zhang, hao dong, weiwu ren, yang wang.* asymmetric α‑regioselective [3+2] annulation of morita−baylis−hillman carbonates: construction of three contiguous stereocenters with vicinal quaternary carbon centers. j. org. chem. 2022, 87, 9593. 19. xiaochen tian, yongxing zhang, weiwu ren, yang wang.* synthesis of functionalized 3,2'-pyrrolidinyl spirooxindoles via domino 1,6-addition/annulation reactions of para-quinone methides and 3-chlorooxindoles. org. chem. front. 2022, 9, 615. (cover page) 20. michael meanwell, steven m. silverman, johannes lehmann, bharanishashank adluri, yang wang, ryan cohen, louis-charles campeau, robert britton.* a short de novo synthesis of nucleoside analogs. science 2020, 369, 725. 21. yang wang,* wen-xiong zhang, zhenfeng xi. carbodiimide-based synthesis of n-heterocycles: moving from two classical reactive sites to chemical bond breaking/forming reaction. chem. soc. rev. 2020, 49, 5810. 22. yang wang, qian wang, jieping zhu.* organocatalytic nucleophilic addition of hydrazones to imines: synthesis of enantioenriched vicinal diamines. angew. chem. int. ed. 2017, 56, 5612. 23. yang wang, yue chi, wen-xiong zhang,* zhenfeng xi.* regioselective ring expansion of 2,4-diiminoazetidines via cleavage of c╟n and c(sp3)-h bonds: efficient construction of 2,3-dihydropyrimidinesulfonamides. j. am. chem. soc. 2012, 134, 2926. 24. yang wang, wen-xiong zhang,* zitao wang, zhenfeng xi.* procedure-controlled selective synthesis of 5-acyl-2-iminothiazolines and their selenium and tellurium derivatives by convergent tandem annulation. angew. chem., int. ed. 2011, 50, 8122. 二、博士研究生招生要求 1. 具有有机合成或者药物合成等相关背景。 2. 具有一定的有机化学理论基础和实验操作技能。 欢迎有意向的同学发送个人简历、科研论文等相关材料至电子邮箱wangyang@ouc.edu.cn |
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