| 查看: 681 | 回复: 11 | |||
[交流]
K-CSC-生命科学博士招生
|
|||
|
2026年伦敦国王学院csc项目招生啦！如果你对心脏疾病的诊断和治疗感兴趣，并且想研发或者拓展医学影像mri在疾病诊治中的应用，欢迎联系。更多详细信息请见项目简介： if you are passionate in a phd project to diagnose and treat heart disease using powerful mri and pet imaging and novel cell-based therapies come and work with us at king’s college london. https://kcl-mrcdtp.com/project/m ... ponse-to-treatment/ https://www.kcl.ac.uk/study-lega ... hip-programme-k-csc https://www.kcl.ac.uk/study/post ... uirements#section-3 project title: molecular imaging signatures of fibrosis to detect heart failure and response to treatment scientific basis: heart failure (hf) affects ~1 million people in the uk (64 million in the world) and is a major driver of morbidity, mortality and nhs costs. cardiac fibrosis (cf), characterised by the excessive accumulation of collagen types 1 and 3 in the myocardium, drives hf. however, current imaging technologies do not directly measure cf, and no specific antifibrotic drugs are available. thus, developing non-invasive imaging technologies and testing the efficacy of new treatments to diagnose and treat cardiac fibrosis selectively is a largely unmet clinical need. overarching aims: this project will use cutting-edge cardiac mri and newly developed imaging probes to non-invasively detect cardiac fibrosis and provide in vivo biomarkers to diagnose heart failure. the developed biomarkers will then be used to measure the therapeutic efficacy of clinically used and novel anti-fibrotic factors, and the effects of biological sex on therapeutic response. the project will answer the clinically important question whether molecular imaging of collagens can provide readouts for precision imaging of cardiac fibrosis to detect hearts at risk of failing, monitor and guide the development of effective therapeutics to prevent heart failure. objectives: 1. profile the expression of collagen types 1 and 3 in cardiac fibrosis and determine whether molecular mri of these collagens quantifies cardiac fibrosis and relates to the development of hf in rodents (year 0-1). 2. utilise the developed imaging methodology to assess the therapeutic efficacy of clinically used and novel antifibrotic factors (e.g., chrdl1 and fam3c) delivered via adeno-associated vectors (year 1-2.5). 3. test whether cardiac fibrosis and the efficacy of two novel anti-fibrotic factors depend on biological sex (year 2.5-4.0). imaging data will be complemented by tissue analysis, including histology, immunohistochemistry, gene expression, and protein immunoblotting. techniques: animal research training; in vivo cardiac molecular mri (and pet if needed), histology and fluorescence microscopy; cell culture; pcr; western blotting; image analysis, statistics. (e) the rotation will teach: 1) histology & microscopy. heart sections from mice with myocardial infarction will be stained with masson’s trichrome and picrosirius red (for infarct size and total collagen) and immunostained with antibodies for col1, col3, and fibroblast activation protein (fap) to detect activated fibroblasts. 2) in vivo cardiac molecular mri. the student will shadow cardiac mri scans in mice to learn how to acquire and analyse images to measure cardiac function (e.g. end-diastolic & systolic volumes, ejection fraction) and molecular imaging (area of enhancement after administration of an mri probe). to apply you will also need a english language exam. both supervisors have excellent track record in the field and supervising students and are excited to work with enthusiastic and committed students on projects that would lead to new discoveries. if you are interested for further details please contact dr alkystis phinikaridou alkystis.1.phinikaridou@kcl.ac.uk 此项目适合有医学或生物学背景的同学，期待具有动物实验和基础医学实验技能和经验的同学。有意向者欢迎发送邮件至导师邮箱： alkystis.1.phinikaridou@kcl.ac.uk 。如果有其他的问题，也欢迎留言，会不定期的查看回复，如果可以的话也麻烦大家分享给适合的同学， 祝大家都能找到心仪的岗位和机会。 For applications through the King’s China Scholarship scheme please contact the supervisor Dr. Alkystis Phinikaridou at alkystis.1.phinikaridou@kcl.ac.uk to discuss the project and get support on how to apply. [ Last edited by ll_l on 2025-10-17 at 20:47 ] |
回复此楼» 猜你喜欢
281求调剂（0805）
已经有8人回复
-
环境领域全国重点实验室招收博士1-2名
已经有3人回复
-
材料专硕306英一数二
已经有10人回复
-
301求调剂
已经有6人回复
-
一志愿天津大学化学工艺专业（081702）315分求调剂
已经有7人回复
-
302求调剂
已经有6人回复
-
26博士申请
已经有3人回复
-
268求调剂
已经有3人回复
-
311求调剂
已经有10人回复
-
被我言中：新模板不强调格式了，假专家开始管格式了
已经有4人回复
» 抢金币啦！回帖就可以得到:
-
物理学 调剂
+1/85
-
温州大学吕晶晶课题组2026年招生
+1/84
-
2026年重庆工商大学管理科学与工程专业学术硕士招生调剂，风景总在柳暗花明处
+1/36
-
天津工业大学航空航天博士招生
+1/35
-
青岛大学泰山学者课题组招2026年申请考核制博士
+1/33
-
澳大利亚西澳大学（UWA）张金强课题组招收全奖博士生（化工新能源方向）
+1/27
-
南开大学罗景山教授课题组招收2026年入学博士生（光/电催化方向）
+2/14
-
【2026博士招生/博后招聘】北京航空航天大学潘彪课题组——AI芯片设计方向
+1/11
-
南京医科大学-膜蛋白结构与功能课题组-招收2026级博士研究生
+1/11
-
【全奖招生】北师港浸大ESLAS实验室招收密码工程/网络安全/计算机视觉博士/博士后
+1/10
-
【博士招生】武汉科技大学招收材料、化工、环境、冶金类2026年“申请-考核”制博士生
+1/8
-
南京林业大学化学工程学院柏惺峰课题组招收2026年申请考核制博士2名
+1/7
-
福州大学国家级人才汤育欣教授课题组2026年招收”申请考核制“储能电池方向博士研究生
+1/6
-
南方科技大学生命科学学院基础免疫与微生物学系招收博士后
+1/4
-
2026年上海大学王亮课题组招收电催化或光催化研究背景的博士生
+2/4
-
首次招收资格，招收工科调剂！
+1/3
-
论文投出，祈福，求好运
+1/3
-
上海交通大学化学化工学院张智涛课题组诚聘博士后
+1/2
-
药学专硕一志愿苏大本科苏大寻求B区高校调剂名额
+1/1
-
中国科学院地球化学研究所招科研助理
+1/1
| For applications through the King’s China Scholarship scheme please contact the supervisor Dr. Alkystis Phinikaridou at alkystis.1.phinikaridou@kcl.ac.uk to discuss the project and get support on how to apply. |
12楼2025-10-17 20:46:50
简单回复
tfang2楼
2025-10-06 15:51
回复
tzynew3楼
2025-10-06 15:54
回复
ll_l(金币+1): 谢谢参与
k 发自小木虫手机客户端
2025-10-06 16:27
回复
ll_l(金币+1): 谢谢参与
2025-10-06 16:34
回复
ll_l(金币+1): 谢谢参与
2025-10-06 16:39
回复
ll_l(金币+1): 谢谢参与
XG-WUST7楼
2025-10-06 17:29
回复
ll_l(金币+1): 谢谢参与
up 发自小木虫IOS客户端
nono20098楼
2025-10-06 19:27
回复
ll_l(金币+1): 谢谢参与
·
kingluck9楼
2025-10-06 20:20
回复
ll_l(金币+1): 谢谢参与
s9659z10楼
2025-10-06 22:21
回复
ll_l(金币+1): 谢谢参与
lymjjh11楼
2025-10-06 22:41
回复
ll_l(金币+1): 谢谢参与
