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北京石油化工学院2026年研究生招生接收调剂公告
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gundnir

木虫 (著名写手)

[交流] 求助一句话的翻译(生物学方面的)

p300 null MSI+ cancer cell lines that re-express exogenous p300 showed slower growth and a more flattened morphology.
这句话是什么意思啊?在线等,请勿机译。
该句所在的文字环境是:
The role of p300 and CBP in cancer is under debate. Some studies indicate a role as tumor suppressors, yet other studies suggest a role as tumor promoters. It has been reported that p300 behaves as a classical tumor suppressor gene. Another study reported that the p300 gene and the CBP gene are mutated in >85% of micro-satellite instable (MSI)+ colon cancer cell lines and primary tumors. p300 null MSI+ cancer cell lines that re-express exogenous p300 showed slower growth and a more flattened morphology.

[ Last edited by gundnir on 2009-11-1 at 01:38 ]

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onlliu

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原来是这样,那还真不太好译了,不过null可以做及物动词,译为使无效,所以还得根据专业知识来翻了.

[ Last edited by onlliu on 2009-11-1 at 16:03 ]
2楼2009-11-01 00:26:58
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gundnir

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引用回帖:
Originally posted by onlliu at 2009-11-1 00:26:
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对外生p300进行重表的p300-0 MSI+ 肿瘤细胞株显示出较慢的生长和较为平坦的形貌.
p300 p300-0应该是试样编号,MSI+应该是某种病理的名称,猜可能是肌肉硬化之类的.

p300是个酶的名称。MSI+是微卫星不稳定性
3楼2009-11-01 01:36:12
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