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yexuqing木虫之王 (文学泰斗)
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Evolution of interorganismal strigolactone biosynthesis in seed plants
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Evolution of interorganismal strigolactone biosynthesis in seed plants 种子植物间独角麦内酯生物合成的进化 ▲ 作者：ANQI ZHOU, ANNALISE KANE, SHENG WU, KAIBIAO WANG, MICHELL SANTIAGO, YUI ISHIGURO, KAORI YONEYAMA, MALATHY PALAYAM, NITZAN SHABEK, AND YANRAN LI ▲链接： https://www.science.org/doi/10.1126/science.adp0779 ▲摘要： 己糖内酯（SLs）是一种小的信号分子，参与与其他植物和土壤微生物的信号传递，并参与植物的生长发育。虽然对SL的功能作用已经有了很好的描述，但对种子植物中SL生物合成的进化却知之甚少。研究者利用合成生物学方法鉴定了细胞色素P450酶CYP722C的功能，该酶催化卡拉内酯酸（CLA）转化为标准SLs的关键步骤。 CYP722A是CYP722C的进化前身，可将CLA转化为非规范的SL-16-羟基CLA，主要存在于茎中，并参与控制茎的分支。16-羟基cla通过两种酶转化为其他可能的生物活性形式的SLs，因此CYP722A的生物合成被认为是典型SLs进化的关键步骤。 ▲ Abstract： Strigolactones (SLs) are small signaling molecules that are involved in signaling with other plants and soil microbes and in plant growth and development. Although the functional roles of SLs are well characterized, less is known about the evolution of SL biosynthesis in seed plants. Zhou et al. leveraged a synthetic biology approach to identify the function of a cytochrome P450 enzyme, CYP722C, that catalyzes a critical step in the conversion of carlactonoic acid (CLA) to canonical SLs. CYP722A, an evolutionary predecessor of CYP722C, converts CLA into a noncanonical SL, 16-hydroxy-CLA, that is primarily detected in shoots and involved in control of shoot branching. 16-hydroxy-CLA is converted to other likely bioactive forms of SLs by two enzymes, so its biosynthesis by CYP722A is proposed to be a critical step in the evolution of canonical SLs. 气候Climate |
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