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[½»Á÷] SUNY-Binghamton University, BME, Yuan Wan's Team

Position description
Dr. Yuan Wan, an Associate Professor in the Department of Biomedical Engineering at SUNY-Binghamton University, is seeking a highly motivated and skilled Postdoctoral Scholar for a full-time position with a duration of up to 5 years, starting in Spring 2025. This is an exceptional opportunity for an ambitious researcher to work on cutting-edge projects focused on liposome/lipid nanoparticle-based disease diagnosis and drug delivery. The ideal candidate will have experience with advanced lipid chemistry, including the understanding of different lipid classes, membrane dynamics, chemical modification of lipids, lipid formulation optimization, liposome/lipid nanoparticle preparation and characterization, cargo loading, and relevant experiments. Candidates with experience in mRNA vaccine delivery systems or CRISPR-Cas technologies are especially encouraged to apply. Research examples can be found here (PMID: 38464277 and PMID: 38374413, ). The successful candidate will have the opportunity to collaborate closely with leading experts, including Dr. Luke Lee at Harvard Medical School, and will have the flexibility to be based either in Binghamton, NY, or Boston, MA.

Key Responsibilities:
I. RESEARCH (90%)
•        Research activity (70%):
•        Lead a research group and determine research goals for a project exploring the advanced immunoliposome/lipid nanoparticles.
•        Design and execute innovative experiments, including method selection, data analysis, and result interpretation.
•        Collaborate with Dr. Wan and Dr. Lee to drive research projects forward, contributing to both fundamental science and translational applications.
•        Develop novel lipid-based biomedical applications.
•        Mentor graduate and undergraduate students in method development and implementation, experiment design, and result interpretation.

•        Publication (10%):
•        Disseminate research findings through high-impact, peer-reviewed journals, either independently or in collaboration with members of the research team.

•        Grant Acquisition (10%):
•        Contribute to the design and preparation of research grant proposals to secure funding for ongoing and future projects.

II. PROFESSIONAL COMPETENCE AND ACTIVITY (10%)
•        Actively participate in relevant professional societies and conferences.
•        Review research proposals and scientific publications.
•        Present research findings at conferences, seminars, and to professional and public interest groups.

Qualifications:
Basic Requirements:
•        Ph.D. degree in lipid chemistry, biomedical engineering, or a related field
•        Extensive experience in lipid formulation selection and optimization.
•        Proficiency in immunoliposome/lipid nanoparticle preparation and characterization techniques, including FRET, TEM, fluorescence microscope, BCA assay, Laurdan assay, DSC, AFM, Zeta, DLS, Nanosight.
•        Skills in cargo loading/release characterization
•        Skills in cell/animal studies, including various cell assays and tumor xenograft mice model; alternatively, skills in PCR, RPA, ARMS-PCR, or asymmetric-PCR, primer/probe design
•        Experience in writing manuscripts and creating scientific illustrations for publications

Preferred Qualifications
•        Experience in mentoring and training graduate and undergraduate students.
•        Experience in supervising a laboratory team.

Application Document Requirements
•        Curriculum Vitae
•        A representative publication demonstrating relevant skills
•        Contact information for 2-3 referees
Salary
Salary will be commensurate with experience and qualifications, following NIH salary guidelines.

Inquiries:
For further information, please contact Dr. Yuan Wan at ywan@binghamton.edu.
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