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This decision has been reached in light of the comments made by the referees. The detailed remarks are appended below.Reviewers' comments:> Reviewer 1: "*************" seemed to contain sufficient material for publication purpose. However, unfortunately, the authors did not address sufficiently what are the main advantages of this particular detection technique over previously reported ones.*************Overall, the English language proved to be insufficient for publication purpose and needs to be revised. Specific care should be taken with regards to prepositions since it can alter the meaning of a statementEditor:> Unfortunately, the reviewer has recommended against publication of this work in ***. In examining the reviewer's specific comments, I note that some of the comments mirror those that I made when the manuscript was initially submitted. In particular, the reviewer indicates that the authors have still not made a convincing case for the advantages of the proposed method over earlier techniques. Given these considerations, I must regrettably recommend rejection of this manuscript.¾ÍÒòΪûÓÐÓÃÐÄд³öÎÄÕµÄÓŵãÀ´£¬¾ÍÕâÑù±»±ÐµôÁË£¬¸Ðµ½·Ç³£Í´ÐÄ£¬½ÌѵÉî¿Ì£¡    ½ÓÏÂÀ´£¬ÎÒÓÖÌôÑ¡ÁËÒ»¸öÔÓÖ¾£¬ÎÒ×ÔÈÏΪӦ¸ÃºÜÈÝÒ×ÖУ¬ÒòΪÎÒÔÚÄǸöÔÓÖ¾ÉÏ¿´µ½ÓÐÀàËÆµÄÎÄÕ£¬ÇÒÎÒ×ÔÈÏΪÄÚÈÝ»¹²»ÈçÎҵĺ㮿ÉÊÇÁ½±¾ÔÓÖ¾ÊôÓÚ²»Í¬µÄ³ö°æ¼¯ÍÅ£¬ÒýÓÃÎÄÏ׵ĸñʽÍêÈ«²»Í¬£¬ÓÖÍ´¿àµÄ»¨ÁËÒ»¸öÍíÉϰÑÎÄÏ׸ñʽ¸ÄÁ˹ýÀ´£¬ÕâÖÖ¹¤×÷¾ÍºÍ×öÕëÏß»î²î²»¶à£¬Õö×ÅÑÛ¾¦ÔÚ¿´£¬Äã²»Äܼ±£¬Ò»¼±¾ÍÓôÃÆµÄ²»µÃÁË£®ÓÚÊǺõ£¬ÓÖÊÇÒ»·­ÉÏ´«µÄÍ´¿à¾­Àú£¬¿ÉÊÇ£¬²»µ½Á½Ì죬²»ÐÒÓÖ½µÁÙÁË£¬¾ÓÈ»ÈÏΪÎҵĸå¼þ²»ÊʺϸÃÔÓÖ¾£¬Ëµ°×ÁË£¬¾ÍÊDz»ÏëÒªÂDear Dr***,I am writing to you on behalf of Editor ****.We regret to inform you that **** is unable to accept your manuscript *******, Manuscript No. ABC-00938-2007 for publication in *****.In view of the limited number of pages available to us each year to cover the entire field of analytical and bioanalytical chemistry, its instrumental advances and its wide range of applications, we can only publish a selection of the papers submitted to our journal.We are sorry not to be able to send you better news.Õâ¸öʱºò£¬Ê²Ã´ÇéÐ÷¶¼ÓÐÁË£¬ÓÐʱºòÏ룬ÊDz»ÊÇ×Ô¼ºµÄ¹¤×÷»¹Ã»Óй»µÄÉϵµ´Î£¿ÊDz»ÊÇÎÄÕÂÕæµÄдµÄºÜ²î£¬ÒòΪ»¹Ã»ÓнÓÊÕ¹ý£Ó£Ã£ÉÂÛÎÄ£¬ËùÒÔÕâ¸öʱºòµÄ×ÔÐÅÐÄÕæµÄÊǷdz£µÄ²î£¬ºóÀ´¸É´à°ÑÎÄÕÂÁÀÔÚÁËÒ»±ß£®ÐÄÇ鯽¾²ÏÂÀ´ÁËÓÖÏ룬»¨ÁËÕâô¶àÐÄ˼×öµÄ¶«Î÷£¬ÊDz»¿ÉÄÜ·ÅÆúµÄ£¬¿öÇÒµ±³õÔÚÑ¡Õâ¸öÌâÄ¿µÄʱºò¾ÍÈÏΪÕâ¸ö¹¤×÷»¹ÊÇÓÐÒ»¶¨Òâ˼ºÍÒâÒåµÄ£®ÓÚÊÇ£¬ÎÒ¸ù¾Ý֮ǰÉó¸åÈ˵ÄÒâ˼£¬ÓÖ²¹³äÁËһЩʵÑ飬ÔÚд×÷ÉÏÒ²·á¸»ÁËһЩ£®¹ýÁËÒ»¸ö¶àÔ£¬ÎÒÓÖ¿ªÊ¼ÁËеijå»÷£®ÕâÒ»´Î£¬ÏÔÈ»£¬Å¬Á¦µÃµ½»Ø±¨ÁË£®Dear professor ***,> We have received expert review of your manuscript. You will see that revision of your manuscript is advised, and suggestions are offered for improving the manuscript and it's impact. If you are prepared to undertake the work required, I would be pleased to consider the paper for publication in Talanta.> For your guidance, reviewers' comments are appended below.Reviewers' comments:> Overall, this is a paper that deserves to be published, but requires revision.(ÓÐÕâÒ»¾ä¾Í¹»ÁË£¬µ±Ê±ÐÄÇ鳬ºÃ£¬ÎÞ·¨ÐÎÈÝ£©ÏóÏÂÃæÕâÑùµÄÒâ¼û£¬Ò²ÊǷdz£Öпϵ쬏ÐлÉó¸åÈË£¬¸Ðл±à¼­£¬¸Ðл£Ã£Ã£Ô£Ö£¡General comments:> The English used in this paper requires major revision. I do not underestimate the challenge of writing a scientific paper in a language that is not the native tongue. However, the science is currently being complicated by the grammar of the paper. In particular, single/plural conflicts and changes of (and inappropriate use of) tenses (see especially section 2.5 where the middle third of the text switches to the present tense). Improving the paper in this way would ensure that the reader can focus upon the science1. The discussions throughout the manuscript is superficial, thus thorough and comprehensive discussions are required in the section of "Results and Discussion".> 2. Conclusion should not be a duplication of the Abstract.µ±È»£¬Ò²Ìá³öÁËÆäËûµÄ²»ÉÙÒâ¼û£¬Õâ´ÎÎÒ¿ÉÊǶԴýµÄÏ൱ÈÏÕæ£¬ÆäÖÐÓÐÒ»ÌõÉó¸åÒâ¼ûÎÒ²»Ì«Ã÷°×£¬Îª´ËÎÒÔÚijרҵÂÛÎÄÉÏ·¢ÌùºÍ±ðÈËÌÖÂÛÁËÒ»¸ö¶àÐÇÆÚ£®ÐÞ¸ÄÁ˸ö°ÑÔ£¬ÉÏ´«£¬µÚÈýÌ죬ˢÐÂÓʼþ£¬ÊÕµ½À´ÐÅÈçÏ£ºDear professor ***, > I am pleased to confirm that your paper "******" has been accepted for publication in Talanta.> With kind regards, ½ÓÏÂÀ´½²½²ÎҵĵڶþƪJournal title: Electrochemistry Communications¡¡£¨3.48·Ö£©Received at Editorial Office: 23-DEC-2007Article revised: 29-JAN-2008Article accepted for publication: 30-JAN-2008ʵ¼ÊÉÏ£¬ÔÚµÚһƪÎÄÕµÄշת¾­ÀúÖУ¬µÚ¶þƪÎÄÕµÄʵÑéÒѾ­ÔÚ½øÐв¢ÇÒд×÷ÁË£¬ÓÐÁ˵ÚÒ»´ÎµÄ¾­Àú£¬µÚ¶þƪÎÄÕÂÔÚд×÷ÉÏÏÔÈ»ÇáËÉÁËÐí¶à£¬¿¼Âǵ½»¹Óв»¶à¾Ã¿ìÒª·Åº®¼Ù£¬Òò´ËÎÒÔÚ¿¼ÂǰѸå¼þҪôͶһ¸öÉó¸åÖÜÆÚ³¤µãµÄÔÓÖ¾£¬ÄÇôÔÚ¼ÙÆÚÖоͲ»ÐèҪΪ¸å¼þ²ÙÐÄÁË£¬ÒªÃ´¾ÍͶһ¸ö¿ìµãµÄÔÓÖ¾£¬¸É´àÔڷżÙǰ¾Í¸ã¶¨£¬×îºó¾­¹ýȨºâ£¬ÎÒÑ¡ÔñÁ˺óÕߣ®2007Äê12ÔÂ18ÈÕÍí£¬¸å¼þÉÏ´«£¬£±£¹ÈÕ£¬ÊÕµ½»ØÐÅ£¬»¹ÒÔΪÊǾÜÁË£¬ÏÅÒ»Ìø£¬Ô­À´ÊÇÎÄÕ³¤ÁË£¬ÒªËõ¶Ì£®> Electrochemistry Communications> Dear professor ***,> This paper is too long for Electrochemistry Communications which aims to publish short, urgent communications (see Guide for Authors). Please either submit it elsewhere as a full paper or shorten it to Communication Length and resubmit.> For Communication Length please observe the following formula:> Total number of words + 200 x (No of figures + No of tables) < 3000.> Your paper currently contains 2929 words and 4 figures. According to the formula above, this is the equivalent of 3729 words, which is too long for this journal.> Yours sincerely,> R. Compton> Editor in Chief> Electrochemistry Communications>> Electrochemistry Communications> Physical and Theoretical Chemistry Laboratory> South Parks Road> Oxford> OX1 3QZ> UK °´ÕÕÒªÇó£¬×Ð×ÐϸϸµÄËõ¶Ì£¬ÓÖ˳±ãÐÞ¸ÄÈóÉ«ÁËÒ»·­£¬»¨ÁËÒ»¸öÐÇÆÚ£¬ÔÚÎ÷·½µÄÊ¥µ®½ÚµÄǰһÌ죬ÎҰѸå¼þ·¢Á˳öÈ¥£¬µ±Ê±Î÷·½ÕýÔڷż٣¬¿ÉÏë¶øÖª£¬¸å¼þÌÉÔÚÀïÃæºÁÎÞ¶¯¾²£¬´óÔ¼µ½ÁËÔªÔ£¸ÈÕ£¬ÎÒ¾õµÃÒ²Ó¦¸Ã·Å¼Ù¹éÀ´Á˰ɣ¬¿ÉÔõô»¹Ã»ÓиøÎҵĸå¼þÄÇÅÂÊÇ·ÖÅäÒ»¸ö¸å¼þºÅÄØ£¿ÒòΪÕâ¸öÔÓÖ¾ÏòÀ´ËÙ¶ÈÊǺܿìµÄ£¬Í¨³£Ò»¸öÔÂÄÚÍê³É´Ó¸å¼þ½ÓÊܵ½½ÓÊյĹý³Ì£®ÓÚÊÇ£¬ÎÒдÁË·âПø±à¼­£ºDear professor R. ComptonWe have shorten our manuscript entitled "*********" to communication length and resubmitted it to Electrochemistry Communications on 23 December 2007, but have not, as yet, receive the assigned manuscript number. We fear that the manuscript may have been lost and should be grateful if you would let us know whether or not you have received it. If not, we will send our manuscript again. Thank you in advance for your help.Best regards,µÚ¶þÌ죬»Ø¸´ÁË£¬²¢ÇÒÂíÉÏ·ÖÅäÁ˸å¼þºÅ£¬¹ûÈ»ÉϰàÁË£¬¿ÉÄÜÊÇ¼ÙÆÚ¹éÀ´£¬ÉíÐÄÆ£±¹°É£®×ö±à¼­Ò²²»ÈÝÒ×£®ÕâÑù°ë¸ö¶àÔµÄijÌìÔ糿£¬ÒѾ­·Å¼ÙÁË£¬¿ÉÊÇ´óÑ©·â·£¬»Ø²»Á˼Ұ¡£¬¸É´àÔÚ´²ÉÏ˯ÀÁ¾õ£¬Ê¦½ãµÄÒ»¸öµç»°°ÑÎÒ½ÐÐÑÁË£¬ËµÈÃÎÒ²é²éÓʼþ£¬ÎÄÕÂÒªÐ޸쬣±£°ÌìÖ®ÄÚÍê³É£®´ò¿ªµçÄÔ£¬Ò»¸öϲÇìµÄÓʼþÕ¹ÏÖÔÚÎÒÃæÇ°£®> Electrochemistry Communications> Dear professor ***,> We will be pleased to accept your manuscript after revision in the light of the enclosed referee's comments provided they can be attended to within 10 days.> Please submit a letter fully detailing your response to each point raised by the referee along with your revised manuscript.> Yours sincerely,> R. Compton> Editor in Chief> Electrochemistry Communications> Reviewers' comments:> Reviewer #1:> The authors of this manuscript reported a new application of electrochemiluminescence (ECL) method in assaying telomerase activity. In this work, the magnetic beads-based TRAP-ECL assay was found to be a rapid and very sensitive (c.a. 100 fold increase in sensitivity) method to detect telomerase activity in tumor cells, as compared with the conventional TRAP method. This is an important work for the developed novel TRAP-ECL assay may become a first line assay for clinical diagnosis and prognosis of cancer. Additionally, the paper was organized and presented well, and literatures were cited adequately. I recommend publication after minor revisions.> Additional Comments:> 1. A previous important work by Miao and Bard (Anal. Chem. 2004, 76, 5379-5386) on magnetic beads-based ECL for DNA detection should be cited.> 2. The words "?about 100 fold lower than that ?" (page 6, line2) should be changed to "?about 100 fold higher than that ?".   Éó¸åÈ˺ÜÈÏͬÎҵŤ×÷£¬Ð¡Ð¡µÄÐ޸ģ¬ÄÄÒª£±£°Ì죬¸ö°ÑСʱ¾Í¿ÉÒÔÍê³É°¡£®¾ÍÕâÑùºÜ¿ìµÄÍê³ÉÁËÐ޸ģ¬µÚ¶þÌì¾Í½Óµ½Á˼ÓÃ֪ͨ£®ÐÄÀïÄÇÊÇÏ൱µÄ¸ßÐ˵ģ® ССµÄ×ܽ᣺£±Ó¢ÎÄд×÷£ºÁ½ÆªÎÄÕÂÈ«²¿ÊÇÓÉÎÒÒ»¸öÈ˲ٵ¶Ð´³É£¬ÆÚ¼ä³ýÁ˵ÚһƪÎÄÕÂÕÒһλÀÏʦ¸ÄÁ˼¸¸ö¾ä×Ó£¬Äܹ»µÃµ½·¢±í£¬ËµÃ÷×îÖÕÓ¢ÎĵÄд×÷»¹ÊÇ´ï±êÁË£®ÎÒµÄÐĵÃÄǾÍÊÇÄ£·Â£¬Ã»´í£¬¿´±ðÈËÔõôд£¬ÔÙÌ×Óã¬ËµÊµ»°£¬ÎÒÃÇ×Ô¼ºÐ´µÄ¾ä×ÓÓм¸¾äÄÜÐŵĹýÄØ£¿Ëµµ½Ä£·Â£¬ÄÇÒ²±ØÐëÔĶÁ¹ý´óÁ¿µÄÎÄÏ×£¬µ±Äãд×÷¿¨×¡µÄʱºò£¬ÄãµÃÏëµÃµ½ÎÒÔÚÄÄÀï¿´µ½¹ýÀàËÆµÄ¾ä×Ó²ÅÐУ®ÎÒǰºó¿´¹ýµÄÎÄÏ×´ó¸ÅÓУ²£°£°Æª×óÓÒ£®£²Í¶¸åÔÓÖ¾µÄÑ¡Ôñ£º´ÓÎҵľ­ÀúÀ´¿´£¬ÏÔÈ»²¢²»ÄÜÒÔ×Ô¼ºµÄÖ÷¹ÛÏ뷨ΪÐÅÌõ£¬ÓÐʱºòÄãÈÏΪºÃµÄ£¬ÊʺϵÄÔÓÖ¾ÏÔÈ»²¢²»ÊʺÏÄ㣬µ±È»£¬Õâ²»Ò»¶¨ÊÇÄãµÄÎÄÕ²»ÊʺÏijijÔÓÖ¾£¬¸ü¿ÉÐŵÄÀíÓÉÊÇÄãµÄ¸å¼þÇ¡ºÃ²»ÊʺÏij¸öÉó¸åÈ˵Äθ¿Ú£®£³·Ç³£ÈÏÕæµÄ¶Ô´ýÉó¸åÈ˵ÄÒâ¼û£º¾¡¿ÉÄÜÏêϸµÄ»Ø´ðÉó¸åÈ˵ÄÎÊÌ⣬ÄÇÅÂÊÇÄã×Ô¼ºÈÏΪ¶¼Ð´µÄÓеãÂÞàÂÁ˶¼Ã»¹ØÏµ£®Éó¸åÈËÊÇÓиÐÇéµÄÂï
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