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23010402

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lixiaod001

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23010402(½ð±Ò+1,VIP+0):Äܲ»ÄÜÈÏÕæµã¡£¡£¡£ 10-15 20:27
A randomized double-crossover experimental design, multi-dose administration. 18 healthy volunteers were randomly divided into two groups, in the administration of the first 3 days and delivery will be accepted diet. 3rd day diet according to the design point in time blood, the first 4 days oral administration of two kinds of preparations were two groups of volunteers in medication after 0.5 h, 1.0 h, 2.0 h, 3.0 h, 4.0 h, 5.0 h, 6.0 h, 7.0 h, 8.0 h, 10.0 h, 12.0 h, 24.0 h blood collection. Two weeks later, into the second cycle, the cross taking the same dose of the reference preparation or test formulation. 2-cycle blood samples obtained by HPLC-UV determination of drug concentration to calculate the relevant pharmacokinetic parameters. "
2Â¥2009-10-15 20:03:16
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YAN8013

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23010402(½ð±Ò+9,VIP+0): 10-26 15:59
Use randomized double-crossover experimental design and multi-dose administration.18 healthy volunteers were divided into 2 groups randomly and were asked to accept diet control since 3 days before administration to the end of the administration. On the 3rd day of diet control draw blood at the designed time point .On the 4th day volunteers in the two groups were asked to take the two kinds of preparation respectively by mouth. Draw blood at  0.5 h¡¢1.0 h¡¢2.0 h¡¢3.0 h¡¢4.0 h¡¢5.0 h¡¢6.0 h¡¢7.0 h¡¢8.0 h¡¢10.0 h¡¢12.0 h¡¢24.0 h after preparation was taken. 2 weeks later, the second cycle began, and the volunteers were asked to take crosswise the same dose of the reference preparation or test product. Test drug concentration of the blood samples drawn during the 2 cycles using HPLC-UV and calculate the relevant pharmacokinetic parameters.
3Â¥2009-10-25 14:43:45
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