| ²é¿´: 2874 | »Ø¸´: 1 | ||
6226758ľ³æ (ÕýʽдÊÖ)
|
[ÇóÖú]
2241586-20-7µÄScifinderºÏ³É·ÏߺÍÏà¹Ø×¨Àû
|
| °ïæ²éÒ»ÏÂ2241586-20-7µÄScifinderºÏ³É·ÏߺÍÏà¹Ø×¨Àû¡£¶àл£¡ |
» ²ÂÄãϲ»¶
085600²ÄÁÏÓ뻯¹¤329·ÖÇóµ÷¼Á
ÒѾÓÐ9È˻ظ´
283Çóµ÷¼Á 086004¿¼Ó¢¶þÊý¶þ
ÒѾÓÐ5È˻ظ´
ÉúÎïѧµ÷¼Á
ÒѾÓÐ5È˻ظ´
ũѧ0904 312Çóµ÷¼Á
ÒѾÓÐ4È˻ظ´
¸´ÊÔµ÷¼Á
ÒѾÓÐ9È˻ظ´
²ÄÁÏÓ뻯¹¤µ÷¼Á
ÒѾÓÐ35È˻ظ´
µ÷¼ÁÇóÊÕÁô
ÒѾÓÐ10È˻ظ´
Ò»Ö¾Ô¸¹þ¹¤´ó 085600 277 12²Ä¿Æ»ùÇóµ÷¼Á
ÒѾÓÐ18È˻ظ´
0831ÉúÒ½¹¤µÚÒ»ÂÖµ÷¼Áʧ°ÜÇóÖú
ÒѾÓÐ9È˻ظ´
ÉúÎïѧ308Çóµ÷¼Á£¨Ò»Ö¾Ô¸»ª¶«Ê¦´ó£©
ÒѾÓÐ6È˻ظ´
baiyuefei
°æÖ÷ (ÎÄѧ̩¶·)
·çÑ©
- LS-EPI: 1647
- Ó¦Öú: 4642 (¸±½ÌÊÚ)
- ¹ó±ö: 46.97
- ½ð±Ò: 658662
- É¢½ð: 11616
- ºì»¨: 995
- ɳ·¢: 81
- Ìû×Ó: 69434
- ÔÚÏß: 13334.1Сʱ
- ³æºÅ: 676696
- ×¢²á: 2008-12-18
- ÐÔ±ð: GG
- רҵ: ºÏ³ÉÒ©Îﻯѧ
- ¹ÜϽ: Óлú½»Á÷
¡¾´ð°¸¡¿Ó¦Öú»ØÌû
¸Ðл²ÎÓ룬ӦÖúÖ¸Êý +1
|
Á´½Ó: https://pan.baidu.com/s/1v2Bt-ZYLE7gaUbs4O2TK-w ÌáÈ¡Âë: auij ¸´ÖÆÕâ¶ÎÄÚÈݺó´ò¿ª°Ù¶ÈÍøÅÌÊÖ»úApp£¬²Ù×÷¸ü·½±ãŶ ¸ÃÎïÖÊËùÒÔÎÄÏ×¾Í1ƪÖÐÎÄרÀû Preparation of [(isoxazol-4-yl)methoxy]spiro compounds useful for the treatment of FXR mediated diseases By: Li, Xiaochuan China, CN108218852 A 2018-06-29 | Language: Chinese, Database: CAplus The invention relates to spiro compounds of formula I, method for their preparation and their use for the treatment of FXR mediated diseases. Compounds of formula I, where R1 is (un)substituted 5- to 10-membered (hetero)aryl; R2 is H, (halo)C1-3alkyl and C3-6cycloalkyl; Z is (un)substituted 5- to 10-membered (hetero)aryl; A is N, CH and C(OH); D, E, F, G are independently (CH3)1-4, and their pharmaceutically acceptable salts, solvates, N-oxides, etc., are claimed. Example compound II was prepared via a multistep procedure (procedure given). The spiro compound can effectively treat farnesol X r¡ |
2Â¥2023-12-18 12:03:07













»Ø¸´´ËÂ¥