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1. з¢ÏÖµÄ RNA ÐÞÊλúÖÆ¼°ÆäÔÚÉúÀíºÍ²¡Àí»·¾³ÖеÄ×÷Ó㬰üÀ¨¸Éϸ°û¡¢·¢Óý¡¢°©Ö¢ºÍÉñ¾­ÏµÍ³¼²²¡¡£ÎÒÃÇÒ²¶Ôϸ°û/¶¯ÎïÄ£Ð͵ĻúÖÆÑо¿ºÍÁÙ´²Ç°ÖÎÁÆ¿ª·¢¸ÐÐËȤ¡£
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±¾ÊµÑéÊÒµÄÑо¿Ê¹Óø÷ÖÖ¿çѧ¿ÆµÄ¹¤¾ß¡£³ýÁËÎÒÃÇ·¢Õ¹µÄRNA 2D/3D ·ÖÎöµÄ»¯Ñ§ºÍ¼ÆËã·½·¨Í⣬ÎÒÃÇ»¹Ê¹Óø÷ÖÖ RNA Ïà¹Ø¼²²¡µÄ¶¯ÎïÄ£ÐÍ¡¢iPS/ÀàÆ÷¹ÙÄ£ÐͺÍÈËÀ໼ÕßÑù±¾¡£ ²©Ê¿ºó½«»á½Ó´¥µ½ÓëRNAÏà¹ØµÄ¸÷¸öÁìÓòÇ°ÑØµÄÎÊÌâºÍ¼¼Êõ¡£ÕâÖÖÅàѵ»·¾³¶ÔÓÚÓÐÐËȤÔÚѧÊõ½çıÇóÖ°Òµ»òÔÚÖÆÒ©ÐÐÒµµ£ÈοÆÑ§Á쵼ְλµÄ¸öÈËÀ´Ëµ·Ç³£ÓмÛÖµ¡£ÔÚÎÒÃǵÄÖ§³ÖÏ£¬¿ÎÌâ×éµÄµÚһλ²©Ê¿ºóÕÅÃô½ÜÒѾ­ÓÚ 2023 ÄêÔÚÌì½òÒ½¿Æ´óѧ¿ªÉèÁË×Ô¼ºµÄʵÑéÊÒ¡£
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1.        Zhang, ¡­, and Lu* 2023. PNAS. A snoRNA-tRNA network governs codon-biased cellular states.
2.        Velema* and Lu* 2023. JACS Au. Chemical RNA Cross-Linking: Mechanisms, Computational Analysis, and Biological Applications.
3.        Zhang ¡­ Lu* 2022 Genome Research. Classification and clustering of RNA crosslink-ligation data reveal complex structures and homodimers.
4.        Van Damme, ¡­, Lu* and Velema*. 2022 Nature Comm. Chemical Reversible Crosslinking Enables Measurement of RNA 3D Distances and Alternative Conformations in Cells. Recommended by Faculty Opinions (https://facultyopinions.com/article/741670636).
5.        Zhang ¡­ Lu*. 2021 Nature Comm. Optimized photochemistry enables analysis of dynamic RNA structuromes and interactomes in genetic and infectious diseases.
6.        Lu* et al. 2020 Nature Comm. Structural modularity of the XIST ribonucleoprotein complex.
7.        Lu et al. 2016 Cell. RNA duplex map in living cells reveals higher order transcriptome structure. Featured on the cover and in a paperclip of Cell, Youtube: Get an Eye-full (Eiffel), https://www.youtube.com/watch?v=1GXibPeUUGQ, on the cover of ¡°Best of Cell 2016¡±. Highlighted in Nature Methods, Nature Chemical Biology, Molecular Cell, Trends in Biochemical Sciences, Faculty Opinions and F1000Prime.
8.        Lu et al. 2015 RNA. Metazoan tRNA introns generate stable circular RNAs in vivo. 21:1-12
9.        Lu et al. 2014 Genome Biology. RIP-seq analysis of eukaryotic Sm proteins identifies three major categories of Sm-containing ribonucleoproteins.

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PSC300

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