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I would encourage the author's to revisit the LOQ calculation as the signal is the height of the peak after background subtraction. While the calculation is correct, how do the authors define the standard deviation of the background since it was removed? Was error propagation performed in this case? The data in Fig 7 does not show the background, which would help convince the reader. Please be rigorous in the important LOQ estimate. ÎÒ×öµÄÊǵ绯ѧ·ÖÎö·½Ïò£¬ÔÚ×öÇúÏߵĹý³ÌÖÐÓÉÓÚµçÈݱ³¾°½Ï´ó£¬µ¼ÖÂDPVÇúÏß»ùÏß²»ÊÇÆ½µÄ£¬ËùÒÔÎÒ½«ÇúÏßµÄDPVÇúÏß¼õÈ¥Á˿հ׵ÄDPVÇúÏߣ¬¾ÍÊǿ۳ýÁ˱³¾°£¬µ«ÊÇÔÚ¼ÆËã¼ì³öÏ޺Ͷ¨Á¿ÏÞʱ£¬Éó¸åÈËÎÊÁËÕâÑùÒ»¸öÎÊÌ⣬˵ÎÒ¼ÈÈ»°Ñ±³¾°¿Û³ýÁËÎÒÔõôµÃµ½µÄ¿Õ°×Ðźŵıê׼ƫ²î£¬Í¬ÑùÈç¹ûÎÒÓÃÒ»¸ö¿Õ°×DPVÔÙ¿Û³ý±³¾°µÄ»°»á²»»áÓÖ½øÐÐÁËÎó²î´«²¥¡£ ȷʵ²»ÖªµÀÔõôÐÞ¸ÄÔõô»Ø¸´ÁË£¬Ï£ÍûÄܵõ½´ó¼ÒµÄ°ïÖú£¬²»Éõ¸Ðл£¡£¡£¡ |
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