一、博士招生专业和方向
招生专业:药物化学
研究方向:活性天然产物全合成、天然产物导向的合成方法学、药物合成
二、博士研究生招生需求
1. 欢迎具有有机合成、药物合成等相关背景的学生加入攻读博士学位。
2. 热爱科研,具有一定的理论基础和实验技能,动手能力强,在相关领域发表过sci论文;具有较强的工作责任心和团队协作精神;具有较强的英文读写能力。
三、导师介绍
任为武,教授,博士生导师,山东省泰山学者青年专家,2019年中国海洋大学“青年英才工程”一层次引进人才。2006年本科毕业于南开大学,2011年在北京大学获得有机化学博士学位(导师:杨震教授、陈家华教授)。之后在瑞士洛桑联邦理工学院(EPFL)从事博士后研究(导师:Jieping Zhu教授)。2016年至2019年在加拿大西蒙弗雷泽大学(SFU)从事博士后研究(导师:Robert Britton教授、Andrew Bennet教授)。在有机化学、天然产物化学、药物化学等领域具有丰富的经验。在Nat. Commun.、Angew. Chem. Int. Ed.、ACS Catal.、Chem. Sci.、Green Chem.、Org. Lett.、J. Nat. Prod.等国际顶尖学术期刊上发表具有重要影响力的学术论文数十篇。担任Org. Lett.、J. Org. Chem.等国际期刊的审稿人。
代表性论文:
1. Luo, F.; Dong, H.; Ren, W.*;Wang, Y.*Organocatalytic asymmetric synthesis of tetrahydroquinolines from ortho-aminophenylpara-quinone methides. Org. Lett. 2022, 24, 7727. (IF: 6.072)
2. Pan, Y.; Ren, W.*; Zhang, Z.; Luo, F.; Hou, X.; Li, X.; Yang, Y.-F.*; Wang, Y.*Tandem 1,6-addition/cyclopropanation/rearrangement reaction of vinylogous para-quinone methides with 3-chlorooxindoles: construction of vicinal quaternary carbon centers. Org. Chem. Front.2022, 9, 3697. (IF: 5.456)
3.Tian, X.; Zhang, Y.; Dong, H.; Ren, W.*;Wang, Y.*Asymmetric α‑regioselective [3 + 2] annulation of Morita−Baylis−Hillman carbonates: construction of three contiguous stereocenters with vicinal quaternary carbon centers. J. Org. Chem.2022, 87, 9593. (IF: 4.198)
4. Akintola, O.; Ren, W.; Adabala, P. J. P.; Bhosale, S.; Wang,Y.; Ganga-Sah, Y.; Britton, R.; Bennet, A. J.*Glycoside hydrolase catalysis: do substrates and mechanism-based covalent Inhibitors react via matching transition states? ACS Catal.2021, 11, 9377. (IF: 13.700)
5. Ren, W.; Farren-Dai, M.; Sannikova, N.; Swiderek, K.; Wang, Y.; Akintola, O.; Britton, R.*; Moliner, V.*; Bennet, A. J. * Glycoside hydrolase stabilization of transition state charge: new directions for inhibitor design. Chem. Sci.2020, 11, 10488. (IF: 9.969)
6. Ren, W.; Gries, R.; Kurita, K. L.; McCaughey, C. S.; Alamsetti, S. K;Tu, L.; Linington, R. G.*; Gries, G.*;Britton, R.* Isolation, structure elucidation, and total synthesis of dolichovespulide, a sesquiterpene from dolichovespulayellowjackets. J. Nat. Prod. 2019,82, 2009.(IF: 4.803)
7. Ren, W.; Pengelly, R.; Farren-Dai, M.; Shamsi Kazem Abadi, S.; Oehler, V.; Akintola, O.; Draper, J.; Meanwell, M.; Chakladar, S.; Świderek, K.; Moliner, V.; Britton, R.*; Gloster, T.*; Bennet, A. J.* Revealing the mechanism for covalent inhibition ofglycoside hydrolases by carbasugars at an atomiclevel. Nat. Commun. 2018, 9, 3243. (IF: 17.694)
8. Ren, W.; Gries, R.; McCaughey, C.; Derstine, N.; Alamsetti, S. K.; Kurita, K. L.; Tu, L.; Linington, R. G.*; Britton, R.*; Gries, G.* Maculatic acids-sex attractant pheromone components of bald-faced hornets. Angew. Chem. Int. Ed.2018, 57, 11618. (IF: 16.823)
9. Ren, W.;Wang, Q.; Zhu, J.* Total synthesis of (±)-strictamine. Angew. Chem. Int. Ed. 2016, 55, 3500. (IF: 16.823)
10. Ren, W.; Wang, Q.; Zhu, J.* Total synthesis of (±)-aspidophylline A. Angew. Chem. Int. Ed. 2014, 53, 1818. (IF: 16.823)
11. Ren, W.; Tappin, N.; Wang, Q.; Zhu, J.* Synthetic study towards strictamine: the oxidative coupling approach. Synlett2013, 1941. (IF: 2.170)
12. Ren, W.; Bian, Y.; Zhang, Z.; Shang, H.; Zhang, P.; Chen, Y.; Yang, Z.*; Luo, T.*; Tang, Y.* Enantioselective and collective syntheses of xanthanolides involving a controllable dyotropic rearrangement of cis--lactones. Angew. Chem. Int. Ed. 2012, 51, 6984. (IF: 16.823)
13. Ren, W.; Chen, Z.; Xiao, Q.; Li, Y.; Sun, T.; Zhang, Z.; Ye, Q.; Meng, F.; You, L.; Zhao, M.; Xu, L.; Tang, Y.; Chen, J.*; Yang, Z.* Diastereoselective total synthesis of (±)-schindilactone A, part 3: the final phase and completion. Chem. Asian J. 2012, 7, 2341. (IF: 4.839)
14. Xiao, Q. #; Ren, W.#(co-first author); Chen, Z.; Sun, T.; Li, Y.; Y, Q.; Gong, J.; Meng, F.; You, L.; Liu, Y.; Zhao, M.; Xu, L.; Shan, Z.; Shi, Y.; Tang, Y.; Chen, J.*; Yang, Z.* Diastereoselective total synthesis of (±)-schindilactone A. Angew. Chem. Int. Ed. 2011, 50, 7373. (IF: 16.823)
有意向的同学请发送个人简历等相关材料至电子邮箱renweiwu@ouc.edu.cn |