±±¾©Ê¯ÓÍ»¯¹¤Ñ§Ôº2026ÄêÑо¿ÉúÕÐÉú½ÓÊÕµ÷¼Á¹«¸æ
²é¿´: 885  |  »Ø¸´: 24
¡¾½±Àø¡¿ ±¾Ìû±»ÆÀ¼Û22´Î£¬×÷Õßwanggch123Ôö¼Ó½ð±Ò 19 ¸ö
µ±Ç°Ö÷ÌâÒѾ­´æµµ¡£

[×ÊÔ´] ¡¾ÆäËû¡¿·ÖÏí Advances in Medicinal Chemistry

Advances in Medicinal Chemistry

Author: B.E. Maryanoff, A.B. Reitz
Publisher: Elsevier Science (April 15, 1999)
Media: Hardcover, 336 pages
Price: $93.30
ISBN-10: 0762300647
ISBN-13: 9780762300648
Volume 4 of Advances in Medicinal Chemistry is comprised of six chapters on a wide range of topics in medicinal chemistry, including molecular modeling, structure-based drug design, organic synthesis, peptide conformational analysis, biological assessment, structure-activity correlation, and lead optimization. Chapter 1 presents an account about amino acid-based peptide mimetics corresponding to b-turn, loop, helical motifs in proteins as a probe of ligand-receptor and ligand-enzyme molecular interactions. Chapter 2 addresses new facets of the medicinal chemistry of the important anticancer drug Taxol® (paclitaxel). Chapter 3 relates an account of the search for new drugs for the treatment of malaria based on the natural product artemisinin. Chapter 4 applies computational chemistry to the evaluation of compound libraries for biological testing. Chapter 5 describes the construction of a 3-dimensional molecular model of the human thrombin receptor, the first protease-activated G-protein coupled receptor (PAR-1), as a means to explore the intermolecular contacts involved in agonist peptide recognition. Finally, Chapter 6 describes the research conducted at Merck on inhibitors of farnesyl transferase as a potential treatment for human cancers.
ÏÂÔØµØÖ·

http://www.namipan.com/d/0762300 ... 195f0c44e33f0bfea00
¶à¶àÆÀ¼ÛŶ£¡
»Ø¸´´ËÂ¥
ÒÑÔÄ   »Ø¸´´ËÂ¥   ¹Ø×¢TA ¸øTA·¢ÏûÏ¢ ËÍTAºì»¨ TAµÄ»ØÌû

xuxuan

ľ³æ (ÖøÃûдÊÖ)


¡ï¡ï¡ï¡ï¡ï ÎåÐǼ¶,ÓÅÐãÍÆ¼ö

²»´íµÄ×ÊÁÏ£¬Ö§³ÖÒ»ÏÂ
6Â¥2009-09-25 12:16:36
ÒÑÔÄ   »Ø¸´´ËÂ¥   ¹Ø×¢TA ¸øTA·¢ÏûÏ¢ ËÍTAºì»¨ TAµÄ»ØÌû

zhantian3529

Ìú¸Ëľ³æ (ÕýʽдÊÖ)


¡ï¡ï¡ï ÈýÐǼ¶,Ö§³Ö¹ÄÀø

good
7Â¥2009-09-25 13:58:19
ÒÑÔÄ   »Ø¸´´ËÂ¥   ¹Ø×¢TA ¸øTA·¢ÏûÏ¢ ËÍTAºì»¨ TAµÄ»ØÌû

chemosky

ÖÁ×ðľ³æ (ÖøÃûдÊÖ)


¡ï¡ï¡ï¡ï¡ï ÎåÐǼ¶,ÓÅÐãÍÆ¼ö

ºÜºÃ£¬¶àл·ÖÏí£¡
8Â¥2009-09-25 14:18:48
ÒÑÔÄ   »Ø¸´´ËÂ¥   ¹Ø×¢TA ¸øTA·¢ÏûÏ¢ ËÍTAºì»¨ TAµÄ»ØÌû

chemosky

ÖÁ×ðľ³æ (ÖøÃûдÊÖ)


1

ºÜºÃ£¬¶àл·ÖÏí£¡
9Â¥2009-09-25 14:19:22
ÒÑÔÄ   »Ø¸´´ËÂ¥   ¹Ø×¢TA ¸øTA·¢ÏûÏ¢ ËÍTAºì»¨ TAµÄ»ØÌû

huyongmin

Í­³æ (³õÈëÎÄ̳)


Ì«ÀÏÁË£¬¼ÈÈ»ÊǽøÕ¹£¬Ó¦¸ÃÊÇ×îеIJÅÐа¡
10Â¥2009-09-25 16:03:04
ÒÑÔÄ   »Ø¸´´ËÂ¥   ¹Ø×¢TA ¸øTA·¢ÏûÏ¢ ËÍTAºì»¨ TAµÄ»ØÌû

flylife

Ìú¸Ëľ³æ (ÖªÃû×÷¼Ò)


¡ï¡ï¡ï ÈýÐǼ¶,Ö§³Ö¹ÄÀø

thanks
12Â¥2009-09-25 19:10:37
ÒÑÔÄ   »Ø¸´´ËÂ¥   ¹Ø×¢TA ¸øTA·¢ÏûÏ¢ ËÍTAºì»¨ TAµÄ»ØÌû

luoqinfly

Òø³æ (СÓÐÃûÆø)


¡ï¡ï¡ï¡ï¡ï ÎåÐǼ¶,ÓÅÐãÍÆ¼ö

·Ç³£¸Ðл
15Â¥2009-09-25 23:37:49
ÒÑÔÄ   »Ø¸´´ËÂ¥   ¹Ø×¢TA ¸øTA·¢ÏûÏ¢ ËÍTAºì»¨ TAµÄ»ØÌû

threeu

ľ³æ (ÕýʽдÊÖ)


¡ï¡ï¡ï ÈýÐǼ¶,Ö§³Ö¹ÄÀø

¿´¿´¡£Ð»Ð»·ÖÏí£¡
19Â¥2009-09-26 09:01:26
ÒÑÔÄ   »Ø¸´´ËÂ¥   ¹Ø×¢TA ¸øTA·¢ÏûÏ¢ ËÍTAºì»¨ TAµÄ»ØÌû

teresaseed

ľ³æ (ÖøÃûдÊÖ)


¡ï¡ï¡ï ÈýÐǼ¶,Ö§³Ö¹ÄÀø

¿´¿´ÔÙ˵ ÄØ
23Â¥2009-09-26 19:04:43
ÒÑÔÄ   »Ø¸´´ËÂ¥   ¹Ø×¢TA ¸øTA·¢ÏûÏ¢ ËÍTAºì»¨ TAµÄ»ØÌû
¼òµ¥»Ø¸´
2009-09-25 07:41   »Ø¸´  
 
huwj1233Â¥
2009-09-25 08:40   »Ø¸´  
 
qiuneng4Â¥
2009-09-25 10:44   »Ø¸´  
 
zws7255Â¥
2009-09-25 12:10   »Ø¸´  
 
xiaoshm11Â¥
2009-09-25 18:48   »Ø¸´  
 
lithium590613Â¥
2009-09-25 21:17   »Ø¸´  
 
wanghu301914Â¥
2009-09-25 21:31   »Ø¸´  
 
fox-fox16Â¥
2009-09-25 23:41   »Ø¸´  
 
androman8917Â¥
2009-09-26 01:40   »Ø¸´  
 
zhouxr18Â¥
2009-09-26 08:32   »Ø¸´  
 
moonboat20Â¥
2009-09-26 09:25   »Ø¸´  
 
xqy200921Â¥
2009-09-26 09:33   »Ø¸´  
 
zhongcm22Â¥
2009-09-26 14:56   »Ø¸´  
 
2009-09-26 22:37   »Ø¸´  
 
cato25Â¥
2009-09-27 00:34   »Ø¸´  
 
Ïà¹Ø°æ¿éÌø×ª ÎÒÒª¶©ÔÄÂ¥Ö÷ wanggch123 µÄÖ÷Ìâ¸üÐÂ
¡î ÎÞÐǼ¶ ¡ï Ò»ÐǼ¶ ¡ï¡ï¡ï ÈýÐǼ¶ ¡ï¡ï¡ï¡ï¡ï ÎåÐǼ¶
×î¾ßÈËÆøÈÈÌûÍÆ¼ö [²é¿´È«²¿] ×÷Õß »Ø/¿´ ×îºó·¢±í
[¿¼ÑÐ] 275Çóµ÷¼Á +10 Micky11223 2026-03-25 14/700 2026-03-28 15:48 by Micky11223
[¿¼ÑÐ] ±¾¿ÆË«·Ç²ÄÁÏ£¬¿ç¿¼Ò»Ö¾Ô¸»ªµç085801µçÆø£¬283Çóµ÷¼Á£¬ÈκÎרҵ¶¼¿ÉÒÔ +5 ֥ʿѩbaoo 2026-03-28 6/300 2026-03-28 15:25 by 1018329917
[¿¼ÑÐ] Ò»Ö¾Ô¸ÏÃÃÅ´óѧ»¯Ñ§Ñ§Ë¶307Çóµ÷¼Á +10 y7czhao 2026-03-26 10/500 2026-03-28 14:23 by ÌÆãå¶ù
[¿¼ÑÐ] Çó»¯Ñ§µ÷¼Á +4 wulanna 2026-03-28 4/200 2026-03-28 13:37 by ÌÆãå¶ù
[¿¼ÑÐ] 0703»¯Ñ§Çóµ÷¼Á +9 ÄÌÓͲÝÝ®. 2026-03-22 10/500 2026-03-28 13:30 by ÌÆãå¶ù
[¿¼ÑÐ] 349Çóµ÷¼Á +6 ½Ü˹ËþÀï˹ 2026-03-21 6/300 2026-03-28 13:12 by ÌÆãå¶ù
[¿¼ÑÐ] 269ר˶Çóµ÷¼Á +10 ½ð¶÷±´ 2026-03-21 10/500 2026-03-27 15:10 by caszguilin
[¿¼ÑÐ] 08¿ªÍ·275Çóµ÷¼Á +4 À­Ë­²»ÖØÒª 2026-03-26 4/200 2026-03-27 14:12 by Delta2012
[¿¼ÑÐ] 315µ÷¼Á +4 0860Çóµ÷¼Á 2026-03-26 5/250 2026-03-27 11:23 by wangjy2002
[¿¼ÑÐ] 314Çóµ÷¼Á +3 ÏªÔÆçæ 2026-03-26 3/150 2026-03-27 11:20 by sanrepian
[¿¼ÑÐ] 325Çóµ÷¼Á +5 Àî¼Îͼ¡¤S¡¤Â· 2026-03-23 5/250 2026-03-27 00:42 by wxiongid
[¿¼ÑÐ] 085602 289·ÖÇóµ÷¼Á +8 WWWÎ÷Î÷¸¥Ë¹ 2026-03-24 8/400 2026-03-26 16:33 by ²»³Ôô~µÄ؈
[¿¼ÑÐ] Ò»Ö¾Ô¸±±¾©»¯¹¤´óѧ²ÄÁÏÓ뻯¹¤£¨085600£©296Çóµ÷¼Á +9 µ¾ÆÞС±à 2026-03-26 9/450 2026-03-26 16:16 by ²»³Ôô~µÄ؈
[¿¼ÑÐ] 297Çóµ÷¼Á +6 ÌïºéÓÐ 2026-03-26 6/300 2026-03-26 15:55 by ²»³Ôô~µÄ؈
[¿¼ÑÐ] 302Çóµ÷¼Á +4 ½õÒÂÎÀÌÙ½· 2026-03-25 4/200 2026-03-25 16:29 by ¹¦·ò·è¿ñ
[¿¼ÑÐ] 300·Ö£¬²ÄÁÏ£¬Çóµ÷¼Á£¬Ó¢Ò»Êý¶þ +5 ³¬ÔÞµÄ 2026-03-24 5/250 2026-03-24 21:07 by ÐÇ¿ÕÐÇÔÂ
[¿¼ÑÐ] 0703»¯Ñ§µ÷¼Á£¬Çóµ¼Ê¦ÊÕ +7 ÌìÌìºÃÔËÀ´Éϰ¶° 2026-03-24 7/350 2026-03-24 20:26 by peike
[¿¼ÑÐ] 341Çóµ÷¼Á(Ò»Ö¾Ô¸ºþÄÏ´óѧ070300) +5 ·¬ÇÑÍ·--- 2026-03-22 6/300 2026-03-23 23:45 by Txy@872106
[¿¼ÑÐ] 284Çóµ÷¼Á +3 yanzhixue111 2026-03-23 6/300 2026-03-23 22:58 by pswait
[¿¼ÑÐ] 328Çóµ÷¼Á +4 LHHL66 2026-03-23 4/200 2026-03-23 14:55 by lbsjt
ÐÅÏ¢Ìáʾ
ÇëÌî´¦ÀíÒâ¼û