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cheungsober木虫 (正式写手)
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【标题】+【有效期至2009年09月02日】，
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| 成骨细胞在体外染氟培养24 h后，Osterix的表达，与对照组相比较，呈现出低剂量促进表达，高剂量抑制表达的双向反应形式：在0.625-2.5mg/L时表达量呈上升水平，而后随NaF剂量增加，表达下降明显。当NaF剂量为0.625-5mg/L时成骨细胞内基因runx2表达水平均有不同程度增加，随后逐渐下降，至10 mg/L时为最低。Ⅰ型胶原表达方式呈现出典型的双向反应：剂量为0.625-2.5 mg/L时，表达上调；剂量为5-160 mg/L时，表达下调。 |
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wanglu3353
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4楼2009-09-01 07:14:51
cheungsober
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| Osteoblasts cultured in vitro 24 h after NaF, Osterix expression, compared with the control group, showing a low dose of the promotion of the expression of the expression of two-way high-dose inhibitory response form: 0.625-2.5mg / L when the expression on the rise levels, then with NaF dose increased, expression significantly decreased. When the NaF dose of 0.625-5mg / L, within hours of osteoblasts runx2 gene expression levels were increased, then decreased gradually to 10 mg / L when the lowest. The expression of type Ⅰ collagen showing a typical two-way response: a dose of 0.625-2.5 mg / L, the expression of increase; dose of 5-160 mg / L, the expression of down. |
2楼2009-08-31 22:50:31
★ ★ ★ ★ ★ ★
cheungsober(金币+6,VIP+0):谢谢，大哥 9-1 14:19
cheungsober(金币+6,VIP+0):谢谢，大哥 9-1 14:19
| after 24 h in vitro cultivation with NaF, the Osterix expression of Osteoblast showed a dose dependency, namely lower dose (0.625-2.5mg / L) promoted the expression and higher dose (>2.5mg / L) inhibited the expression with the inflexion point of 2.5mg / L. similarly, the expression of runx2 gene kept increasing during the dosage range of 0.625-5mg / L, then turned over and reached the lowest point at the dosage of 10 mg / L. moreover, the expression of type Ⅰ collagen had a similar dose dependent two-way response, which can be described as a increasing expression trend at the dose of 0.625-2.5 mg / L and an inhibited expression tendency in the range of 5-160 mg / L. |
3楼2009-09-01 06:07:25