| 查看: 615 | 回复: 0 | |||
godgoodstudy木虫 (小有名气)
|
[交流]
博士招生[3+2] cycloaddition reaction
|
|
joint supervision between university of rouen & university of florence phd: towards stereocontrolled s-cis and s-trans peptidic bond mimics by regiocontrolled [3+2] cycloaddition reactions. start : october 1st 2022 duration : 36 months missions : in the frame of the graduate school for research xl-chem (https://www.xlchem.fr/), a co-financed joint supervised position is available at umr 6014 cnrs cobra (rouen) and dipartimento di chimica ugo schiff (florence). the phd candidate will implement solid phase peptide synthesis (spps) compatible regiocontrolled [3+2] cycloaddition reactions to mimic either s-cis or s-trans conformation of the peptidic bond, and evaluated the biological activity of obtained polypeptidic scaffolds. activities - organic chemistry - spps - nmr, uv and mass analysis - biological evaluation of pseudopeptides activity - bibliography - research article writing - regular reports skills - master degree in organic synthesis or advanced molecular sciences - chemistry / biology interface context : joint supervision between pr. annamaria papini (florence) and pr. pierre-yves renard (rouen). first 18 months will take place in umr 6014 cnrs cobra (http://www.lab-cobra.fr/) at rouens university, and will be devoted to the implementation of spps compatible methods for the synthesis of diverse heteroaromatic derivatives through [3+2] cycloaddition methods, allowing to mimic either s-cis or s-trans conformation of the peptidic bond with. salary and working contract will be the usual french « contrat doctoral » (1520 � net wages). 18 next months will take place in the interdepartmental laboratory of peptide & protein chemistry & biology, dipartimento di chimica “ugo schiff“ (https://www.chim.unifi.it/) of the universitá degli studi di fierenze. the phd candidate will receive a 1200 � monthly grant to implement the [3+2] cycloaddition methods on spps to synthesize geometrically constrained biologically active polypeptides analogues, study by nmr their 3d conformation, and evaluate their biological activity. required documents : - vitae (1 page) - contact names - summary of research work (<3 pages) application pierre-yves renard: pierre-yves.renard@univ-rouen.fr anna maria papini: annamaria.papini@unifi.it |
回复此楼» 猜你喜欢
极限拉扯，如何抉择
已经有8人回复
-
入职后第一次管课题组的专利缴费，对账才发现官费比别人多掏了一倍
已经有6人回复
-
OpenAI又攻克数学难题了，离AI做有机合成还有多远？
已经有8人回复
-
课题组会帮你通过考核么？
已经有6人回复
-
售一区SCI文章T0P，我:8O.551.O54,科目全,可十急
已经有9人回复
-
售SCI一区T0P文章，我:8.O55.1.O.54,科目全,可十急
已经有8人回复
-
售SCI一区文章，我:8O5.5.1.O5.4,科目全,可伽急
已经有10人回复
-
售SCI一区T0P文章，我:8.O55.1.O.54,科目全,可十急
已经有9人回复
-
售SCI一区文章，我:8.O.55.1.O.54,科目齐全,可伽急
已经有7人回复
-
售SCI文章，我:8O5.5.1.O.54,科目齐全,可+急
已经有10人回复
