>As indicated by the 3rd referee, the progression and therapeutic information is fine but how prognosis is studied is not clear without a follow-up data?(如何进一步对预后进行研究呢)
>
>No validation has been done for key regulatory genes in primary clinical samples. This is essential.
>(关键调控基因需要在最初的临床样品中验证,但是纯生信的我怎么回答呢。。。)