| 查看: 1059 | 回复: 18 | |||
| 【有奖交流】积极回复本帖子，参与交流，就有机会分得作者 zzurh 的 36 个金币 ，回帖就立即获得 1 个金币，每人有 1 次机会 | |||
[交流]
2021年CSC与法国巴黎大学合作奖学金——分子电化学实验室诚招公派博士后两名
|
|||
|
项目一 Title: Development of green oxidation processes using electrochemical O2 Reductive Activation and bioinspired Fe complexes Advisor: Dr. Elodie Anxolabéhère & Dr. Claire Fave e-mail elodie.anxolabehere@u-paris.fr Institution: Laboratoire d’Electrochimie Moléculaire (LEM) UMR 7591 Université de Paris, Bat. Lavoisier, 15 rue J.-A. de Baïf 75205 Paris Cedex 13, France Subject: Context Oxidation reactions are of main importance in the chemical industry for the production of large quantities of organic molecules. Current economic and ecological challenges require development of economically sound and ecologically viable chemical processes such as the use of molecular O2 to conduct oxidation reactions in mild conditions. In Nature, metalloenzymes, such as Fe containing oxygenases, are able to achieve highly efficient and selective oxidations under mild conditions throughout a process known as reductive O2 activation. This process results to the breaking of the O-O bond of O2 bound to the Fe catalytic center and leads to oxygen atom insertion into weakly reactive substrates. The observed reactivity in these processes at the Fe containing active site of the enzymes is a great source of inspiration for developing new earth abundant metal containing molecular catalysts for oxidation reactions. Objectives: In an effort to reproduce the enzymes’ fascinating catalytic performance,we have developed at LEM an original complementary electrochemical and spectroscopic strategy using simple metal complexes as models of the active site, and carbon electrodes to provide the necessary electrons. Fe-peroxo, Fe- hydroperoxo and oxo species have been proposed as key reactive intermediates in the catalytic cycle of Fe containing enzyme (eg. CytP450) capable of cleaving the O-O bond and of inserting oxygen atom in organic substrates. Using Fe porphyrins, we have shown that is possible to reproduce such a catalytic cycle.[4c] Our objectives is now to set up the optimal catalytic conditions (heterogeneous or homogeneous conditions) for electrocatalytic oxidation of organic substrates. Strategy and methodology: In the first part of the project, we will design new complexes by modulating the nature of the chelating ligand. We will study the electrocatalytic activity for various organic substrates oxidation. To reach these objectives, mechanistic studies based on electrochemistry and spectroelectrohemistry will be the key to decipher the parameters that control the reactivity of the FeOOH and FeO reactive species. Rooted in these studies, optimization of the most active catalysts will be pursued, leading to robust and highly selective catalysts. The second part of the project aim at transferring the catalytic activity of Fe catalyst onto surface, since it is also a good way to prevent the use of a large amount of catalyst and to get an active electrode for performing catalysis in water. We will start our investigation with our most active complexes and we design catalytic materials along various strategies, ranging from non-covalent catalyst grafting on carbon nanotubes using weak interactions to covalent grafting of catalyst monolayer on carbon surface. Requirement of the candidates: Expected skills of the PhD candidate: ligand and metal complexes synthesis, molecular electrochemistry, coordination chemistry, spectroscopy, analytical chemistry. The candidate should show a strong interest in experimental work. 项目二 Title: Electrocatalytic processes with molecular catalysts involving Halogen bond interactions. Advisors: Dr Claire Fave and Dr. Audrey Guerlin Mail: claire.fave@u-paris.fr Lab: Laboratoire d’Electrochimie Moléculaire (LEM) UMR 7591 Université de Paris Bat . Lavoisier 15 rue J.-A. de Baïf 75205 Paris Cedex 13 France Description of the subject The use of electrochemical methods for the investigation of Halogen Bonding (XB) in solution is a recent approach [Current Opinion in Electrochemistry 2019]. Most articles have been published during the past 5 years and many aspects are still to be explored. The fundamental concept of electrochemical XB switching for molecular recognition and detection has been well established by our group [Chem. Commun. 2014, PCCP 2016] and P. Beer [Chem. Commun 2015] at Oxford. Taking into account the reported results, electrochemistry can be considered as powerful tool for qualitative and quantitative study of XB as well as a method to control XB strength in supramolecular associations. Also recently the community has started to consider XB in organic synthesis and more importantly in organocatalysis. We have identified a conceptionally new domain, ripe for exploration, that is XB promoted electron transfer reactions involving the activation of covalent bonds. Based on the expertise of our team [Current Opinion in Electrochemistry 2019 and Chem Comm 2019], the present proposal is focused on the exploration of electrocatalytic systems in which XB could promote the formation of an intermediate complex between an electrochemically regenerated mediator and the substrate in solution or at the interface. The results will provide new insight into supramolecular reactivity involving XB, but also the development of electrochemically assisted catalytic redox reactions. For this purpose, the synthesis of new redox active molecules will be performed and their electrochemical and catalytic properties will be systematically studied by spectroscopic, electrochemical and spectro-electrochemical methods. Expected skills of the candidate: organic chemistry, molecular electrochemistry, catalysis. |
回复此楼» 猜你喜欢
081700 调剂 267分
已经有8人回复
-
请教下大家 2026年国家基金申请是双盲审吗？
已经有5人回复
-
276求调剂。有半年电池和半年高分子实习经历
已经有10人回复
-
一志愿南航材料专317分求调剂
已经有4人回复
-
求调剂
已经有4人回复
-
生物学学硕求调剂
已经有5人回复
-
284求调剂
已经有10人回复
-
一志愿山东大学药学学硕求调剂
已经有4人回复
-
07化学280分求调剂
已经有4人回复
-
298-一志愿中国农业大学-求调剂
已经有12人回复
» 本主题相关商家推荐: (我也要在这里推广)
» 抢金币啦！回帖就可以得到:
-
西南交通大学医学院招收生物医学工程和材料与化工专业硕士研究生
+1/187
-
香港中文大学（深圳）靳羽华教授交叉实验室招募2026年材料学博士生（光致变色）
+2/134
-
国自然面上祈福
+1/79
-
散金币，求基金中标！！
+1/60
-
湘潭大学化工学院国家级人才团队2026年博士研究生招生
+1/58
-
武汉高校接受研究生调剂，材料、化学、纺织方向
+2/44
-
2026 物理方向招收部分调剂
+1/33
-
哈尔滨工业大学（深圳）-何自开教授团队诚招化学工程与技术专业博士研究生
+1/33
-
中国科学院杭州医学研究所覃江江课题组招聘博士后
+1/30
-
湖南大学微生物结构与功能实验室2026年计划招收博士研究生
+1/17
-
26年博士自荐
+1/14
-
---大龄的未婚男找结婚女对象
+1/14
-
招收专业代码08的学硕！
+1/14
-
湖南大学微生物结构与功能实验室2026年计划招收博士研究生
+1/13
-
电子信息求调剂
+1/12
-
【博士招生】上海交通大学陈倩栎课题组招收2026年申请-考核博士生1名（能源材料方向）
+1/7
-
26年申博自荐-计算机视觉
+1/5
-
中国科学院上海硅酸盐研究所招聘科研助理
+1/3
-
哈工大马樱教授招收2026级计算机类、集成电路类博士生（报名时间3月30号截止！）
+1/2
-
欢迎加入赣南师范大学先进光电子研究中心
+1/1
18楼2021-02-16 16:19:23
简单回复
tzynew2楼
2021-02-04 22:40
回复
zzurh(金币+1): 谢谢参与
i 发自小木虫Android客户端
nono20093楼
2021-02-04 22:55
回复
zzurh(金币+1): 谢谢参与
。 发自小木虫Android客户端
2021-02-04 23:02
回复
zzurh(金币+1): 谢谢参与
。 发自小木虫Android客户端
2021-02-04 23:36
回复
zzurh(金币+1): 谢谢参与
2021-02-05 00:23
回复
zzurh(金币+1): 谢谢参与
longwave7楼
2021-02-05 03:56
回复
zzurh(金币+1): 谢谢参与
祝福 发自小木虫Android客户端
2021-02-05 07:40
回复
zzurh(金币+1): 谢谢参与
2021-02-05 07:53
回复
BiotageAB10楼
2021-02-05 13:30
回复
zzurh(金币+1): 谢谢参与
。
guanlianwu11楼
2021-02-05 21:15
回复
zzurh(金币+1): 谢谢参与
1
miaojiabing12楼
2021-02-07 14:11
回复
zzurh(金币+1): 谢谢参与
6
slytjiaofei13楼
2021-02-07 14:27
回复
shenrenren14楼
2021-02-07 20:49
回复
zzurh(金币+1): 谢谢参与
guanlianwu15楼
2021-02-08 11:38
回复
slytjiaofei16楼
2021-02-08 12:29
回复
psylhh17楼
2021-02-11 18:53
回复
zzurh(金币+1): 谢谢参与
icebergwu19楼
2021-02-19 16:05
回复
zzurh(金币+1): 谢谢参与
