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zjandzq金虫 (正式写手)
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翻译一段药学相关的（请专业人士进），谢谢！！
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A solution of disodium L-glutamate was formed by adding 8.0 g of sodium hydroxide to a suspension of 14.7 g (0.1 mole) of L-glutamic acid in 70 ml of water and 50 ml of acetone. Sodium hydroxide (6 g) in 20 ml water and 25.0 g(0.11 mole) of lauroyl chloride were added dropwise at 5 C over a period of about 1 hr. Stirring was continued at 0 C for 2 hr and the reaction mixture was acidified to pH 1 with 6N hydrochloric acid to precipitate crystalline N-lauroyl-L- glutamic acid. The crude crystals (32.6 g) were washed with petroleum benzine and 27.6 g of purified N-lauroyl-L-glu- tamic acid were obtained (yield 84.0%), mp 102-105C, neutralization equivalence 99.5%, optical rotation [0t]~ ° = -10.5 (C=2, methanol). When D L-glutamic acid was used instead of the L-glu- tamic acid in this reaction and the ratio of water to acetone in the reaction medium was varied, the yield varied as shown in Table II and Figure 1. |
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金虫 (正式写手)
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2楼2009-06-16 22:03:28
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zjandzq(金币+10,VIP+0):虽然问题已经解决了，还是谢谢你！ 6-17 09:12
zjandzq(金币+10,VIP+0):虽然问题已经解决了，还是谢谢你！ 6-17 09:12
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解决钠盐L -谷氨酸形成 增加八点零克氢氧化钠暂停十四点七克 （ 0.1摩尔）的L -谷氨酸70毫升水和50毫升 丙酮。 氢氧化钠（ 6 g ）在二〇毫升水和二十五点○克（ 0.11 摩尔）月桂酰氯分别滴加在5 C号，为期约1小时。搅拌，继续在0 C的2小时 和酸化反应混合物的pH至1 6N 盐酸沉淀结晶氮月桂- L一 谷氨酸。原油晶体（三十二点六克）被洗 石油汽油和二十七点六克净化氮月桂- L一谷氨酸 tamic酸，获得（收益率84.0 ％ ） ，熔点102 - 105C ， 中等价99.5 ％ ，旋光度[ 0吨] 〜 ° = -10.5 （丙= 2 ，甲醇） 。当长度-谷氨酸是代替了L -谷氨酸tamic酸反应和水的比例，以丙酮 在反应介质是多种多样的，不同的收益率 列于表二和图1 。 |
3楼2009-06-17 08:36:01
