| 查看: 525 | 回复: 0 | ||
[求助]
急急急，求助一篇英文文献突然找不到了，只有正文部分内容，麻烦大神帮忙下载原文献
|
|
写毕业论文用到的一篇英文文献突然找不到了，只有正文部分内容，麻烦大神帮忙下载原文献，急急急！ 正文部分内容：Mesenchymal markers such as vimentin and fibronectin are upregulated and redistributed15. These changes cannot be secondary to the loss of E-cadherin, as transfection of E-cadherin is not enough to induce a reversion to an epithelial morphology59. This indicates that Snail must have additional targets that are independent of E-cadherin. Also relevant to EMT is the upregulation of RhoB, which is important for neural-crest development in chick embryos60, and is ectopically expressed in the chick neural tube after overexpression of Slug46.Regulation of this small GTPase, which is involved in actin rearrangements, links Snail and EMT with changes in cell shape and, hence, with the morphogenetic movements that occur during gastrulation and neural-crest delamination. Indeed, a Rho-mediated signalling cascade is crucial for the morphogenetic changes during Drosophila gastrulation, a pathway that involves the exchange factor RhoGEF2 in response to an extracellular signal called folded gastrulation (Fog)61.Considering that, genetically, Fog lies downstream of Snail62, it is tempting to speculate that Rho GTPases might also be indirect targets of Snail in the gastrulating fly. |
回复此楼» 猜你喜欢
碳青霉烯类抗生素为何需联用西司他丁钠？ | Biochempartner
已经有0人回复
-
源自蕨类植物的抗炎美白活性分子去甲氧基荚果蕨素 | Biochempartner
已经有0人回复
-
化学工程及工业化学论文润色/翻译怎么收费?
已经有153人回复
-
肠道里的"代谢开关"：Fexaramine用肠道限制性重新定义 FXR 激动剂
已经有0人回复
-
DMXAA：从血管破坏剂到STING通路研究的关键工具分子 | Biochempartner
已经有0人回复
-
靶向PD-L1的人源化单克隆抗体阿特珠单抗
已经有0人回复
-
"探针之父"(+)-JQ-1如何改变表观遗传研究 | Biochempartner
已经有0人回复
-
含氟糖皮质激素的外用抗炎利器醋酸氟轻松
已经有0人回复
-
阿莫奈韦（Amenamevir）：解旋酶-引物酶靶向分子的结构特征与合成路径全解析
已经有0人回复
-
利瑞鲁单抗：靶向KIR的NK细胞检查点工具抗体，结构基础与科研应用全解析
已经有0人回复
-
Wnt-C59：PORCN靶向化学探针，Wnt信号通路阻断机制与科研应用全解析
已经有0人回复