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lingzi326

荣誉版主 (著名写手)

★ ★ ★
小木虫(金币+0.5):给个红包,谢谢回帖交流
waiy2001(金币+2,VIP+0):谢谢分享交流 9-3 19:54
姓名  何川
单位  芝加哥大学
领域  化学生物学和有机合成方法学
链接  http://he-group.uchicago.edu/index.html

Recent publications
67. Jian, X.; Wasinger, E.C.; Lockard, J.V.; Chen, L.X.; He, C. " Highly Sensitive and Selective Gold(I) Recognition by a Metalloregulator in Ralstonia metallidurans" J. Am. Chem. Soc. 2009, ASAP [pdf]
66. Poor, C.B.; Chen, P.R.; Duguid, E.; Rice, P.A.; He, C. " Crystal structures of the reduced, sulfenic acid and mixed disulfide forms of sarz, a redox active global regulator in staphylococcus aureus" J. Biol. Chem. 2009, Accepted [pdf]
65. Lin, Y.; Zhao, T.; Jian, X.; Farooqui, Z.; Qu, X.; He, C.; Dinner, A. R.; Scherer, N.F. "Using the Bias from Flow to Elucidate Single DNA Repair Protein Sliding and Interactions with DNA" Biophys. J. 2009, 96(5), 1911. [pdf]
64. Yang, S.; Li, Z.; Jian, X; He, C. "Platinum(II)-Catalyzed Intramolecular Cyclization of o-Substituted Arylalkynes through sp3 C-H Activation" Angew. Chem. Intl. Ed. 2009 Early View [pdf]
63.
Wegner, S.V.; Boyaci, H.; Chen, H.; Jensen, M.P.; He, C. "Engineering a Uranyl-Specific Binding Protein from NikR" Angew. Chem. Intl. Ed. 2009, 48 (13), 2339. [pdf] [press]
62. Yi, C.; Yang, C.-G.; He, C. "A Non-Heme Iron-Mediated Chemical Demethylation in DNA and RNA" Acc. Chem. Res. 2009, 42(4), 519. [pdf]  
61. Yang, C.-G.; Garcia, K.; He, C. "Damage Detection and Base Flipping in Direct DNA Alkylation Repair" ChemBioChem 2009, 10 (3), 417. [pdf]  
60. Richter, S; Anderson, V.J.; Garufi, G.; Lu, L.; Budzik, J. M.; Joachimiak, A.; He, C.; Schneewind, O.; Missiakas, D. "Capsule anchoring in Bacillus anthracis occurs by a transpeptidation reaction that is inhibited by capsidin" Mol. Microbiol. 2009, 71 (2), 404. [pdf]  
59. Chen, P.R.; Nishida, S.; Poor, C.B.; Cheng, A.; Bae, T.; Kuechenmeister, L.; Dunman, P.M.; Missiakas, D.; He, C. "A new oxidative sensing and regulation pathway mediated by the MgrA homologue SarZ in Staphylococcus aureus" Mol. Microbiol. 2009, 71 (1), 198. [pdf]
58. Shigdel, U.K. and He, C. "A New 1'-Methylenedisulfide Deoxyribose that Forms an Efficient Cross-Link to DNA Cytosine-5 Methyltransferase (DNMT) J. Am. Chem. Soc. 2008, 130 (52), 17634. [pdf]  
57. Qiu, Z.; Lu, L.; Jian, X.; He, C. "A Diazirine-Based Nucleoside Analogue for Efficient DNA Interstrand Photocross-Linking" J. Am. Chem. Soc. 2008, 130 (44), 14398. [pdf]  
56. Jia, G.; Yang, C.-G.; Yang, S.; Jian, X.; Yi, C.; Zhou, Z.; He, C. "Oxidative demethylation of 3-methylthymine and 3-methyluracil in single-stranded DNA and RNA by mouse and human FTO" FEBS Letters 2008, 582(23-24), 3313. [pdf]  
55. Chen, H.; Hu, J.; Chen, P.R.; Lan, L.; Li, Z.; Hicks, L.M.; Dinner, A.R; He, C. "The Pseudomonas aeruginosa multidrug efflux regulator MexR uses an oxidation-sensing mechanism" Proc. Natl. Acad. Sci. 2008, 105 (36), 13586-13591. [pdf]  
54. Li, X.; Ye, S.; He, C.; Yu, Z.-X. "Mechanisms of Brønsted Acid Catalyzed Additions of Phenols and Protected Amines to Olefins: A DFT Study" Eur. J. Org. Chem. 2008, 25, 4296-4303. [pdf]  
53. Shan, G.; Li, Y.; Zhang, J.; Li, W.; Szulwach, K.E.; Duan, R.; Faghihi, M.A.; Khalil, A.M.; Lu, L.; Paroo, Z.; Chan, A.W.S.; Shi, Z.; Liu, Q.; Wahlestedt, C.; He, C.; Jin, P. "A small molecule enhances RNA interference and promotes microRNA processing"  Nature Biotechnology 2008, 26, 933. [pdf] [C&EN]  
52. Li, Z.; Brouwer, C.; He, C. "Gold-Catalyzed Organic Transformations" Chem. Rev. 2008, 108(8), 3239-3265. [pdf] Submitted for publication in the special issue: Coinage Metals in Organic Synthesis  
51. Yang, C.-G.; Yi, C.; Duguid, E. M.; Sullivan, C. T.; Jian, X.; Rice, P. A.; He, C. "Crystal structures of DNA-RNA repair enzymes AlkB and ABH2 bound to dsDNA" Nature 2008, 452, 961-965. [pdf] [U. Chicago Press] [C&EN] [AAAS] [Argonne Lab Press] (For additional news links, go to "Research Highlights"  
50.  Chen, P.R. and He, C.  "Selective recognition of metal ions by metalloregulatory proteins" Curr. Opin. Chem. Biol. 2008, 12(2), 214-221. [pdf]
49.  Chang, S.; Bray, S.M.; Li, Z.; Zarnescu, D.C.; He, C.; Jin, P.; Warren, S.T.  "Identification of small molecules rescuing fragile X syndrome phenotypes in Drosophila" Nat. Chem. Biol. 2008,  4, 256-263. [pdf]   
48.  Shigdel, U. K.; Zhang, J.; He, C. "Diazirine-Based DNA Photo-Cross-Linking Probes for the Study of Protein-DNA Interactions" Angew. Chem. Intl. Ed. 2008, 47(1), 90-93. [pdf]   
47.  Chen, C.-S.; Korobkova, E.; Chen, H.; Zhu, J.; Jian, X.; Tao, S.-C.; He, C.*; Zhu, H.* "A proteome chip approach reveals new DNA damage recognition activities in Escherichia Coli" Nat. Methods, 2008, 5, 69-74. [pdf] [J. Proteome Res. press]

[ Last edited by lingzi326 on 2009-8-13 at 00:41 ]
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51楼2009-08-12 22:40:09
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lingzi326

荣誉版主 (著名写手)

★ ★ ★
小木虫(金币+0.5):给个红包,谢谢回帖交流
waiy2001(金币+2,VIP+0):谢谢分享交流 9-3 19:55
姓名  Stephen J. Lippard(何川教授的导师)
单位  MIT
领域  bioinorganic chemistry
链接  http://web.mit.edu/lippardlab/

Recent publications
Photoaffinity isolation and identification of proteins in cancer cell extracts that bind to platinum-modified DNA. Evan R. Guggenheim, Dong Xu, Christiana X. Zhang, Pamela V. Chang, and Stephen J. Lippard, ChemBioChem, 10, 141-157 (2009).

Small-Molecule Fluorescent Sensors for Investigating Zinc Metalloneurochemistry. Elizabeth M. Nolan, and Stephen J. Lippard, Acc. Chem. Res., 42, 193-203 (2009).

The state of the art of chemical biology. Karl-Heinz Altmann, Johannes Buchner, Horst Kessler, Francois Diederich, Bernhard Krautler, Stephen Lippard, Rob Liskamp, Klaus Muller, Elizabeth M. Nolan, Bruno Samori, Gisbert Schneider,Stuart L. Schreiber, Harald Schwalbe, Claudio Toniolo, Constant A. A. van Boeckel, Herbert Waldmann, and Christopher T. Walsh, ChemBioChem, 10, 16-29 (2009).

New Strategy for Quantifying Biological Zinc by a Modified Zinpyr Fluorescence Sensor. Xiao-an Zhang, Dugan Hayes, Sarah J. Smith, Simone Friedle, and Stephen J. Lippard, J. Am. Chem. Soc., 130, 15788-15789 (2008).

Organelle-Specific Zinc Detection Using Zinpyr-Labeled Fusion Proteins in Live Cells. Elisa Tomat, Elizabeth M. Nolan, Jacek Jaworski, and Stephen J. Lippard, J. Am. Chem. Soc., 130, 15776-15777 (2008).

Synthesis and Characterization of {Ni(NO)}10 and {Co(NO)2}10 Complexes Supported by Thiolate Ligands. Andrew G. Tennyson, Shanta Dhar, and Stephen J. Lippard, J. Am. Chem. Soc., 130, 15087-15098 (2008).

Tools and Tactics for the Optical Detection of Mercuric Ion. Elizabeth M. Nolan, and Stephen J. Lippard, Chem. Rev., 108, 3443-3480 (2008).

Reactions of Synthetic [2Fe-2S] and [4Fe-4S] Clusters with Nitric Oxide and Nitrosothiols. Todd C. Harrop, Zachary J. Tonzetich, Erwin Reisner, and Stephen J. Lippard, J. Am. Chem. Soc., 130, 15602-15610 (2008).

Bacterial nitric-oxide synthases operate without a dedicated redox partner. [Erratum to document cited in CA149:047515]. Ivan Gusarov, Marina Starodubtseva, Zhi-Qiang Wang, Lindsey McQuade, Stephen J. Lippard, Dennis J. Stuehr, and Evgeny Nudler, J. Biol. Chem., 283, 19164 (2008).

Poly(ADP-ribose) polymerase-1 activity facilitates the dissociation of nuclear proteins from platinum-modified DNA. Evan R. Guggenheim, Alison E. Ondrus, Mohammad Movassaghi, and Stephen J. Lippard, Bioorg. Med. Chem., 16, 10121-10128 (2008).

Targeted delivery of cisplatin to prostate cancer cells by aptamer functionalized Pt(IV) prodrug-PLGA-PEG nanoparticles. Shanta Dhar, Frank X. Gu, Robert Langer, Omid C. Farokhzad, and Stephen J. Lippard, Proc. Natl. Acad. Sci. U. S. A., 105, 17356-17361 (2008).

9-Triptycenecarboxylate-bridged diiron(II) complexes: Capture of the paddlewheel geometric isomer. Simone Friedle, Jeremy J. Kodanko, Kyrstin L. Fornace, and Stephen J. Lippard, J. Mol. Struct., 890, 317-327 (2008).

Targeted Single-Wall Carbon Nanotube-Mediated Pt(IV) Prodrug Delivery Using Folate as a Homing Device. Shanta Dhar, Zhuang Liu, Jurgen Thomale, Hongjie Dai, and Stephen J. Lippard, J. Am. Chem. Soc., 130, 11467-11476 (2008).

Bacterial Nitric-oxide Synthases Operate without a Dedicated Redox Partner. Ivan Gusarov, Marina Starodubtseva, Zhi-Qiang Wang, Lindsey McQuade, Stephen J. Lippard, Dennis J. Stuehr, and Evgeny Nudler, J. Biol. Chem., 283, 13140-13147 (2008).

Synthesis and characterization of a ditriflate-bridged, diiron(II) complex with syn-N-donor ligands: [Fe2(micro -OTf)2(PIC2DET)2](BARF)2. Jeremy J. Kodanko, and Stephen J. Lippard, Inorg. Chim. Acta, 361, 894-900 (2008).

cis-diammine(pyridine)chloroplatinum(II), a monofunctional platinum(II) antitumor agent: uptake, structure, function, and prospects. Katherine S. Lovejoy, Ryan C. Todd, Shuzhong Zhang, Michael S. McCormick, J. Alejandro D'Aquino, Joyce T. Reardon, Aziz Sancar, Kathleen M. Giacomini, and Stephen J. Lippard, Proc. Natl. Acad. Sci. U. S. A., 105, 8902-8907 (2008).

Conjugated Platinum(IV)-Peptide Complexes for Targeting Angiogenic Tumor Vasculature. Sumitra Mukhopadhyay, Carmen M. Barnes, Ariel Haskel, Sarah M. Short, Katie R. Barnes, and Stephen J. Lippard, Bioconjugate Chem., 19, 39-49 (2008).

A 1,2-d(GpG) Cisplatin Intrastrand Cross-Link Influences the Rotational and Translational Setting of DNA in Nucleosomes. Matthias Ober, and Stephen J. Lippard, J. Am. Chem. Soc., 130, 2851-2861 (2008).

Synthesis of dicarboxylate "C-clamp" 1,2-diethynylarene compounds as potential transition-metal ion hosts. Erwin Reisner, and Stephen J. Lippard, Eur. J. Org. Chem., 156-163 (2008).

Bacillus anthracis-derived nitric oxide is essential for pathogen virulence and survival in macrophages. Konstantin Shatalin, Ivan Gusarov, Ekaterina Avetissova, Yelena Shatalina, Linsey E. McQuade, Stephen J. Lippard, and Evgeny Nudler, Proc. Natl. Acad. Sci. U. S. A., 105, 1009-1013 (2008).

A Reversible pH-Dependent Intramolecular Pyridine-Aldehyde Cyclization. Xiao-an Zhang, Datong Song, and Stephen J. Lippard, J. Org. Chem., 73, 734-737 (2008).

Iron Complexes of Dendrimer-Appended Carboxylates for Activating Dioxygen and Oxidizing Hydrocarbons. Min Zhao, Brett Helms, Elena Slonkina, Simone Friedle, Dongwhan Lee, Jennifer DuBois, Britt Hedman, Keith O. Hodgson, Jean M. J. Frechet, and Stephen J. Lippard, J. Am. Chem. Soc., 130, 4352-4363 (2008).
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52楼2009-08-13 00:38:50
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lingzi326

荣誉版主 (著名写手)

★ ★ ★
小木虫(金币+0.5):给个红包,谢谢回帖交流
waiy2001(金币+2,VIP+0):谢谢分享交流 9-3 19:55
姓名  Christopher J. Chang
单位  UC Berkeley
领域  Uses inorganic and organic chemistry, molecular biology, and chemical biology approaches to explore new frontiers of science
链接  http://www.cchem.berkeley.edu/cjcgrp/

Recent publications
Albers, A. E.; Dickinson, B. C.; Miller, E. W.; Chang, C. J."A Red-Emitting Naphthofluorescein-Based Fluorescent Probe for Selective Detection of Hydrogen Peroxide in Living Cells", Bioorg. Med. Chem. Lett. 2008, 18, 5948-5950 (Special Issue in Honor of Benjamin F. Cravatt). [pdf]
Dickinson, B. C.; Chang, C. J."A Targetable Fluorescent Probe for Imaging Hydrogen Peroxide in the Mitochondria of Living Cells", J. Am. Chem. Soc. 2008, 130, 9638-9639. [pdf]
Miller, E. W.; He, Q.; Chang, C. J. "Preparation and Use of Leadfluor-1, a Synthetic Fluorophore for Live-Cell Lead Imaging", Nature Protocols 2008, 3, 777-783. [pdf]
Que, E. L.; Domaille, D. W.; Chang, C. J. "Metals in Neurobiology: Probing Their Chemistry and Biology with Molecular Imaging", Chem. Rev. 2008, 108, 1517-1549. [pdf]
Srikun, D.; Miller, E. W.; Domaille, D. W.; Chang, C. J."An ICT-Based Approach to Ratiometric Fluorescence Imaging of Hydrogen Peroxide Produced in Living Cells", J. Am. Chem. Soc. 2008, 130, 4596-4597. [pdf]
Domaille, D. W.; Que, E. L.; Chang, C. J. "Synthetic Fluorescent Sensors for Studying the Cell Biology of Metals", Nat. Chem. Biol. 2008, 4, 168-175. [pdf] Harman, W. H.; Chang, C. J. "N2O Activation and Oxidation Reactivity from a Non-Heme Iron Pyrrole Platform", J. Am. Chem. Soc. 2007, 129, 15128-15129. [pdf]
Miller, E. W.; Chang, C. J. "Fluorescent probes for nitric oxide and hydrogen peroxide in cell signaling" Curr. Opin. Chem. Biol. 2007, 11, 620-625. [pdf]
Albers, A. E.; Rawls, K. A.; Chang, C. J "Activity-based fluorescent reporters for monoamine oxidases in living cells", Chem. Commun. 2007, 4647-4649. [pdf] Yoon, S.; Miller, E. W.; He, Q.; Do, P. H.; Chang, C. J "A Bright and Specific Fluorescent Sensor for Mercury in Water, Cells, and Tissue", Angew. Chem. Int. Ed. 2007, 46, 6658-6661. [pdf]
Miller, E. W.; Tulyathan, O.; Isacoff, E. Y.; Chang, C. J. "Molecular imaging of hydrogen peroxide produced for cell signaling", Nat. Chem. Biol. 2007, 3, 263-267. [pdf] [C & E News]
Miller, E. W.; Bian, S. X.; Chang, C. J. "A Fluorescent Sensor for Imaging Reversible Redox Cycles in Living Cells", J. Am. Chem. Soc. 2007, 129, 3458-3459. [pdf]
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53楼2009-08-13 00:47:23
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lingzi326

荣誉版主 (著名写手)

国内外专家学者的实验室网页帖子


waiy2001(金币+1,VIP+0):谢谢 9-3 19:57
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54楼2009-08-13 00:49:19
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zdliang83

木虫 (小有名气)

★ ★
小木虫(金币+0.5):给个红包,谢谢回帖交流
waiy2001(金币+1,VIP+0):谢谢,能否给出链接与最新的出版物呢? 9-3 19:58
洪茂椿 院士
男,博士,研究员,中国科学院院士,亚太材料科学院院士,第三世界科学院院士。《Crystal Growth & Design》,《结构化学》和《波谱学》杂志副主编,《Inorg. Chem. Commun.》,《Inorg. Chim. Acta》,《J. Mol. Struct.》,《中国科学B版》和《化学进展》等杂志编委
55楼2009-08-13 11:57:38
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wbc0506

金虫 (小有名气)

Edwin C. Constable

★ ★ ★
小木虫(金币+0.5):给个红包,谢谢回帖交流
waiy2001(金币+2,VIP+0):谢谢你 9-3 19:58
Edwin C. Constable

Department of Chemistry, University of Basel, Spitalstrasse 51, CH-4056 Basel, Switzerland

实验室连接:http://www.chemie.unibas.ch/~constable/index.html

超分子化学领域。
56楼2009-08-13 16:24:06
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chpzhou1383

★ ★ ★
小木虫(金币+0.5):给个红包,谢谢回帖交流
waiy2001(金币+2,VIP+0):谢谢你 9-3 19:58
姓名:蒋民华
单位:山东大学晶体材料国家重点实验室
领域:功能单晶的生长和表征
有机和半有机半有机二阶和三阶非线性光学材料的探索和表征
先进半导体材料的制备

业绩(论文,专著等等)
主要学术成绩:
在DKDP晶体亚稳相生长理论和方法方面取得了有影响的创新成果;在KTP晶体的助熔剂生长方面取得重大突破,开创了用助熔剂法批量生长非线性光学晶体的先河;首次探索并生长出新的非线性光学晶体LAP,并在此基础上形成了有特色的半有机非线性光学材料的新方向。

主要奖励和荣誉:
国家发明一等奖(1988)
国家科技进步二等奖(1987)
国家教委科技进步一等奖(1988、1995、1996)
山东省首届科学技术最高奖(2002)
何梁河利科学技术进步奖(1996)
山东省科技成果一等奖(1981)
山东省科技进步一等奖(1999)
五一劳动奖章和全国优秀科技工作者(1987)
全国先进工作者(1989)
求是杰出科技成就集体奖(2007)
建筑材料科学技术发明一等奖(2007) 论著和专利:
主编《晶体物理》、《功能材料概论》、《神材妙用丛书》
合编《晶体生长》、《无机合成制备化学》
在国内外学术刊物上发表300余篇论文,获发明专利10余项


链接:http://www.icm.sdu.edu.cn/professor/jiangminhua.php
57楼2009-08-17 06:51:54
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chpzhou1383

★ ★ ★
小木虫(金币+0.5):给个红包,谢谢回帖交流
waiy2001(金币+2,VIP+0):谢谢你 9-3 19:59
内容已删除
58楼2009-08-18 05:29:55
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zhaixiren

铜虫 (小有名气)


小木虫(金币+0.5):给个红包,谢谢回帖交流
学习啦,怎么都没有晶体制备方面的专家啊,比如砷化镓、碳化硅方面的牛人呢?!
59楼2009-08-20 01:31:33
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iphyaries

铁杆木虫 (小有名气)

陈创天院士

★ ★
waiy2001(金币+2,VIP+0):谢谢,能否分享一下他的实验室链接与他的paper呢? 9-3 20:00
原福建物构所
现北京理化所
做倍频光电晶体
中国唯一领先世界的领域
虽然有很多争议……
Ineedlearnmore...
60楼2009-08-20 11:47:25
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