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A two-stage method for parameter identification of a nonlinear system in a microbial batch process ÇóÖúÂÛÎĵÄSCI¼ìË÷ºÅ,лл£¡ |
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nandehutu9327: ½ð±Ò+10, ¡ï¡ï¡ï¡ï¡ï×î¼Ñ´ð°¸ 2019-03-08 19:33:03
Ðľ²_ÒÀÈ»: LS-EPI+1, ¸ÐлӦÖú 2019-03-12 13:10:01
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nandehutu9327: ½ð±Ò+10, ¡ï¡ï¡ï¡ï¡ï×î¼Ñ´ð°¸ 2019-03-08 19:33:03
Ðľ²_ÒÀÈ»: LS-EPI+1, ¸ÐлӦÖú 2019-03-12 13:10:01
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A Two-Stage Method for Parameter Identification of a Nonlinear System in a Microbial Batch Process ×÷Õß:Xu, GX (Xu, Gongxian)[ 1 ] ; Lv, DX (Lv, Dongxue)[ 1 ] ; Tan, WX (Tan, Wenxin)[ 1 ] APPLIED SCIENCES-BASEL ¾í: 9 ÆÚ: 2 ÎÄÏ׺Å: 337 DOI: 10.3390/app9020337 ³ö°æÄê: JAN 2 2019 ÎÄÏ×ÀàÐÍ:Article ²é¿´ÆÚ¿¯Ó°ÏìÁ¦ ÕªÒª This paper deals with the parameter identification of a microbial batch process of glycerol to 1,3-propanediol (1,3-PD). We first present a parameter identification model for the excess kinetics of a microbial batch process of glycerol to 1,3-PD. This model is a nonlinear dynamic optimization problem that minimizes the sum of the least-square and slope errors of biomass, glycerol, 1,3-PD, acetic acid, and ethanol. Then, a two-stage method is proposed to efficiently solve the presented dynamic optimization problem. In this method, two nonlinear programming problems are required to be solved by a genetic algorithm. To calculate the slope of the experimental concentration data, an integral equation of the first kind is solved by using the Tikhonov regularization. The proposed two-stage method could not only optimally identify the model parameters of the biological process, but could also yield a smaller error between the measured and computed concentrations than the single-stage method could, with a decrease of about 52.79%. A comparative study showed that the proposed two-stage method could obtain better identification results than the single-stage method could. ¹Ø¼ü´Ê ×÷Õ߹ؼü´Ê:microbial batch process; parameter identification; optimization problem; nonlinear programming; numerical differentiation; genetic algorithm KeyWords Plus:1,3-PROPANEDIOL PRODUCTION; KLEBSIELLA-PNEUMONIAE; GLYCEROL; OPTIMIZATION; DISSIMILATION; BIOCONVERSION; MULTIPLICITY; FERMENTATION; SUBSTRATE; CULTURE ×÷ÕßÐÅÏ¢ ͨѶ×÷ÕßµØÖ·: Xu, GX (ͨѶ×÷Õß) ÏÔʾ¸ü¶à Bohai Univ, Dept Math, 19 Keji Rd, Jinzhou 121013, Peoples R China. µØÖ·: ÏÔʾ¸ü¶à [ 1 ] Bohai Univ, Dept Math, 19 Keji Rd, Jinzhou 121013, Peoples R China µç×ÓÓʼþµØÖ·:gxxu@bhu.edu.cn; dutxgx@aliyun.com; isopeisope@aliyun.com »ù½ð×ÊÖúÖÂл »ù½ð×ÊÖú»ú¹¹ ÊÚȨºÅ National Natural Science Foundation of China 11101051 Liaoning Provincial Natural Science Foundation of China 20180550839 Basic Research Fund of Liaoning Education Department LF2017002 ²é¿´»ù½ð×ÊÖúÐÅÏ¢ ³ö°æÉÌ MDPI, ST ALBAN-ANLAGE 66, CH-4052 BASEL, SWITZERLAND ÆÚ¿¯ÐÅÏ¢ Impact Factor (Ó°ÏìÒò×Ó): Journal Citation Reports Àà±ð / ·ÖÀà Ñо¿·½Ïò:Chemistry; Materials Science; Physics Web of Science Àà±ð:Chemistry, Multidisciplinary; Materials Science, Multidisciplinary; Physics, Applied ÎÄÏ×ÐÅÏ¢ ÓïÑÔ:English Èë²ØºÅ: WOS:000459436300127 ISSN: 2076-3417 ÆäËûÐÅÏ¢ IDS ºÅ: HM4IG Web of Science ºËÐĺϼ¯ÖÐµÄ "ÒýÓõIJο¼ÎÄÏ×": 31 Web of Science ºËÐĺϼ¯ÖÐµÄ "±»ÒýƵ´Î": 0 ²é¿´½ÏÉÙÊý¾Ý×Ö¶Î |
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