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A two-stage method for parameter identification of a nonlinear system in a microbial batch process

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nandehutu9327: ½ð±Ò+10, ¡ï¡ï¡ï¡ï¡ï×î¼Ñ´ð°¸ 2019-03-08 19:33:03
Ðľ²_ÒÀÈ»: LS-EPI+1, ¸ÐлӦÖú 2019-03-12 13:10:01
A Two-Stage Method for Parameter Identification of a Nonlinear System in a Microbial Batch Process
×÷Õß:Xu, GX (Xu, Gongxian)[ 1 ] ; Lv, DX (Lv, Dongxue)[ 1 ] ; Tan, WX (Tan, Wenxin)[ 1 ]

APPLIED SCIENCES-BASEL

¾í: 9  ÆÚ: 2
ÎÄÏ׺Å: 337

DOI: 10.3390/app9020337

³ö°æÄê: JAN 2 2019

ÎÄÏ×ÀàÐÍ:Article

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ÕªÒª
This paper deals with the parameter identification of a microbial batch process of glycerol to 1,3-propanediol (1,3-PD). We first present a parameter identification model for the excess kinetics of a microbial batch process of glycerol to 1,3-PD. This model is a nonlinear dynamic optimization problem that minimizes the sum of the least-square and slope errors of biomass, glycerol, 1,3-PD, acetic acid, and ethanol. Then, a two-stage method is proposed to efficiently solve the presented dynamic optimization problem. In this method, two nonlinear programming problems are required to be solved by a genetic algorithm. To calculate the slope of the experimental concentration data, an integral equation of the first kind is solved by using the Tikhonov regularization. The proposed two-stage method could not only optimally identify the model parameters of the biological process, but could also yield a smaller error between the measured and computed concentrations than the single-stage method could, with a decrease of about 52.79%. A comparative study showed that the proposed two-stage method could obtain better identification results than the single-stage method could.

¹Ø¼ü´Ê
×÷Õ߹ؼü´Ê:microbial batch process; parameter identification; optimization problem; nonlinear programming; numerical differentiation; genetic algorithm

KeyWords Plus:1,3-PROPANEDIOL PRODUCTION; KLEBSIELLA-PNEUMONIAE; GLYCEROL; OPTIMIZATION; DISSIMILATION; BIOCONVERSION; MULTIPLICITY; FERMENTATION; SUBSTRATE; CULTURE

×÷ÕßÐÅÏ¢
ͨѶ×÷ÕßµØÖ·: Xu, GX (ͨѶ×÷Õß)

ÏÔʾ¸ü¶à        Bohai Univ, Dept Math, 19 Keji Rd, Jinzhou 121013, Peoples R China.
µØÖ·:

ÏÔʾ¸ü¶à        [ 1 ] Bohai Univ, Dept Math, 19 Keji Rd, Jinzhou 121013, Peoples R China
µç×ÓÓʼþµØÖ·:gxxu@bhu.edu.cn; dutxgx@aliyun.com; isopeisope@aliyun.com

»ù½ð×ÊÖúÖÂл
»ù½ð×ÊÖú»ú¹¹        ÊÚȨºÅ
National Natural Science Foundation of China        
11101051
Liaoning Provincial Natural Science Foundation of China        
20180550839
Basic Research Fund of Liaoning Education Department        
LF2017002
²é¿´»ù½ð×ÊÖúÐÅÏ¢   
³ö°æÉÌ
MDPI, ST ALBAN-ANLAGE 66, CH-4052 BASEL, SWITZERLAND

ÆÚ¿¯ÐÅÏ¢
Impact Factor (Ó°ÏìÒò×Ó): Journal Citation Reports
Àà±ð / ·ÖÀà
Ñо¿·½Ïò:Chemistry; Materials Science; Physics

Web of Science Àà±ð:Chemistry, Multidisciplinary; Materials Science, Multidisciplinary; Physics, Applied

ÎÄÏ×ÐÅÏ¢
ÓïÑÔ:English

Èë²ØºÅ: WOS:000459436300127

ISSN: 2076-3417

ÆäËûÐÅÏ¢
IDS ºÅ: HM4IG

Web of Science ºËÐĺϼ¯ÖÐµÄ "ÒýÓõIJο¼ÎÄÏ×": 31

Web of Science ºËÐĺϼ¯ÖÐµÄ "±»ÒýƵ´Î": 0

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