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Cell process development Senior Scientist The Scientist, will be responsible for the manufacturing process development and technology transfer of cell and gene therapy programs. He/she will be part of the team responsible for CAR-T process development and validation for autologous and allogeneic cell therapy products. The candidate will be involved in the design, execution and optimization of experiments in a cross-functional matrix team. Key responsibilities include, but are not limited to: • Accountable for development, optimization and execution of new and next generation CAR-T programs • Develop and identify analytical assays to characterize manufacturing process • Provide technical leadership to others and make decision to set direction for a project • Work in a team environment as well as contribute individually to meet project timeline and objectives • Write and review protocols, technical reports, regulatory documents and memos to summarize experiments and investigations • Collaborate with internal and external partners to evaluate and implement process improvements • Interact with cross-functional internal team members and stakeholders • Foster a working environment that encourages the company's commitment to equal employment opportunity and the value of a diverse work force • Other duties will be assigned, as necessary Qualifications • PhD in Biological Sciences, Biochemistry or Immunology OR MS in Biological Sciences or Biochemistry and with at least 3 years of industry experience. • Expertise with primary T-cell culture, viral and non-viral gene delivery methods and cell based functional assays is required. • Background in T-cell biology and immunology is preferred. • Strong technical knowledge in process development and tech transfer of cell therapy products is preferred. • Prior industry and/or experience working in a GMP environment is preferred. • Independently design, execute and troubleshoot experiments, analyze, report and present data. • Candidates must be detail-oriented, highly organized and able to manage multiple tasks, handle tight timelines and deliver quality data • Experience in maintaining written records of work in the form of laboratory notebooks (paper or electronic) and establishing lab protocols/SOPs is required. • Have deep intellectual curiosity, and excellent communication, interpersonal and collaborative skills. • Provide functional and intellectual support to team members. • Must be comfortable handling and processing blood or serum samples. • Occasional weekend work may be required. [ À´×Ô°æ¿éȺ ½ËÕ ] |
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