24小时热门版块排行榜    

北京石油化工学院2026年研究生招生接收调剂公告
查看: 134  |  回复: 2
当前主题已经存档。
当前只显示满足指定条件的回帖,点击这里查看本话题的所有回帖

sxl0539

木虫 (小有名气)

[交流] 急需文献一篇

Akiyama H, Kudo S, Shimizu T. ..... Arzneim-Forsch 35: 1124-1132, 1985. 10.
回复此楼
已阅   回复此楼   关注TA 给TA发消息 送TA红花 TA的回帖

hjw123

铜虫 (正式写手)

★ ★ ★ ★ ★
sxl0539(金币+5,VIP+0): 5-14 00:59
文摘
The absorption, distribution and excretion of a new antithrombotic and vasodilating agent, cilostazol (6-[4-(1-cyclohexyl-1H-tetrazol-5-yl)butoxy]-3,4-dihydro-2(1H)- qui nolinone, OPC-13013) was studied after the oral administration of cilostazol or 14C-cilostazol in rats, rabbits, dogs and man. After the oral administration of 14C-cilostazol at a dose of 10 mg/kg in male and female rats and rabbits, and at a dose of 3 mg/kg in dogs, the Tmax, Cmax and T1/2 of the radioactivity were 2 h, 710.5 ng eq X ml-1 and 2.5 h in male rats, 4 h, 11 002.8 ng eq X ml-1 and 3.7 h in female rats, 8 h, 358.1 ng eq X ml-1 and 6.9 h in rabbits, and 3 h, 559.4 ng eq X ml-1 and 1.6 h in dogs, respectively. After the oral administration of 14C-cilostazol at a dose of 10 mg/kg in rats, tissue concentrations of radioactivity in female rats were about 3 to 5 times as high as those in male rats. The blood and tissue concentrations of radioactivity in male and female rats showed a marked sex difference. However, the concentrations in the blood in both male and female rats declined rapidly. There was no evidence of the accumulation of radioactivity in the tissues due to repeated oral administrations of 14C-cilostazol at a dose of 3 mg/kg once a day for 21 days in male rats.(ABSTRACT TRUNCATED AT 250 WORDS)
3楼2009-05-13 21:25:37
已阅   回复此楼   关注TA 给TA发消息 送TA红花 TA的回帖
查看全部 3 个回答

hjw123

铜虫 (正式写手)

是不是这篇The absorption, distribution and excretion of a new antithrombotic and vasodilating agent, cilostazol, in rat, rabbit, dog and man.

我只有文摘,你要吗?
2楼2009-05-13 21:23:55
已阅   回复此楼   关注TA 给TA发消息 送TA红花 TA的回帖
普通表情 高级回复 (可上传附件)
最具人气热帖推荐 [查看全部] 作者 回/看 最后发表
[考研] 材料考研调剂 +3 Gs大王 2026-04-02 3/150 2026-04-02 00:34 by 2026材料调剂
[考研] 一志愿安徽大学计算机科学与技术学硕,331分求调剂 +3 蒋昌鹏qtj 2026-04-01 3/150 2026-04-01 23:56 by 义文wang
[考研] 材料专硕322分 +10 哈哈哈吼吼吼哈 2026-04-01 10/500 2026-04-01 22:19 by Dyhoer
[考研] 材料调剂 +14 一样YWY 2026-04-01 14/700 2026-04-01 21:07 by lijunpoly
[考研] 材料与化工(0856)304求B区调剂 +8 邱gl 2026-03-30 16/800 2026-04-01 17:58 by 邱gl
[考研] 086502化学工程342求调剂 +7 阿姨复古不过 2026-03-27 7/350 2026-04-01 16:14 by yanflower7133
[考研] 311求调剂 +10 李芷新1 2026-03-31 10/500 2026-04-01 14:38 by chenqifeng666
[考研] 求0861交通运输专硕or材料专硕调剂 +4 勒布朗@ 2026-03-31 4/200 2026-04-01 09:54 by 一只好果子?
[考研] 085701环境工程,267求调剂 +17 minht 2026-03-26 17/850 2026-04-01 09:11 by xiayizhi
[考研] 初试301,代码085701环境工程,本硕一致,四六级已过,有二区一作,共发表5篇论文 +3 axibli 2026-04-01 3/150 2026-04-01 08:43 by i_cooler
[考研] 0856求调剂 +9 楒桉 2026-03-28 9/450 2026-03-31 19:06 by 暮泽12
[考研] 一志愿南昌大学324求调剂 +6 hanamiko 2026-03-29 6/300 2026-03-31 16:35 by hypershenger
[考研] 286求调剂 +5 丢掉懒惰 2026-03-27 8/400 2026-03-31 11:27 by Delta2012
[考研] 调剂求院校招收 +7 鹤鲸鸽 2026-03-28 7/350 2026-03-31 11:21 by oooqiao
[考研] 抱歉 +3 田洪有 2026-03-30 3/150 2026-03-30 19:11 by 迷糊CCPs
[考研] 292求调剂 +13 是妍子也是研子 2026-03-30 13/650 2026-03-30 18:01 by 小徐0109
[考研] 一志愿中南大学化学0703总分337求调剂 +6 niko- 2026-03-27 6/300 2026-03-30 10:25 by herarysara
[考研] 343求调剂 +6 爱羁绊 2026-03-29 6/300 2026-03-29 12:00 by 无际的草原
[考研] 2026年华南师范大学欢迎化学,化工,生物,生医工等专业优秀学子加入! +3 llss0711 2026-03-28 6/300 2026-03-29 10:26 by llss0711
[考研] 266求调剂 +11 阳阳哇塞 2026-03-27 12/600 2026-03-27 17:56 by yu221
信息提示
请填处理意见