| 查看: 667 | 回复: 2 | ||
Ankh吧唧新虫 (小有名气)
|
[求助]
请问药物诱导的小鼠肝损伤模型用什么种类的鼠好一些 已有2人参与
|
|
如题，科研萌新，希望前辈指点。 发自小木虫IOS客户端 |
回复此楼» 猜你喜欢
售SCI文章，我:8.O.5.51O.5.4,科目齐全,可十急
已经有3人回复
-
售SCI文章，我:8.O.5.51O.5.4,科目齐全,可十急
已经有3人回复
-
T^T
已经有3人回复
-
╭(╯ε╰)╮
已经有3人回复
-
T^T
已经有3人回复
-
→_→
已经有4人回复
-
o>_<o
已经有4人回复
-
T^T
已经有5人回复
-
售SCI文章，我:8.O.5.51O.5.4,科目齐全,可十急
已经有3人回复
-
O(∩_∩)O
已经有4人回复
2楼2018-12-27 13:09:06
【答案】应助回帖
|
A study was made in inbred mice of genetic determinants of toxic liver cell injury. Carbon tetrachloride was injected s.c. in sublethal doses to induce liver cell damage in 4 strains of mice, BALB/c, C3H, C57BL/6 and SJL/J. Mice of the SJL/J strain were the least susceptible and showed minor hepatocellular necrosis, which resolved by Day 7, and a slight histiocytic response. C3H and C57BL/6 showed lesions which were intermediate between the other 2 strains. The autoantibody response to LSP was weak, transient and detected only in C57BL/6 mice. Strain differences in mice in carbon tetrachloride-induced liver injury. Br J Exp Pathol. 1983 Oct; 64(5): 524–533. |
3楼2018-12-28 17:16:45