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在zhangwj和yusen_1982版主的共同建议下，发出主题为“好文献天天读”专题橱窗。从而更好的服务与大家，提高人气。 在这里恳请各位有条件下载和手头有好文章的虫友在这里跟帖，发出您们宝贵的资源，大家共享，从而共同获得更多的资源。发扬“我为人人，人人为我”的精神。 跟帖请求：【主题】：-------（参考本版分类） 【题目】：---------- 【内容简介或者提纲】-------------- 【下载】------ 在此谢谢各位！！对发资源文献的虫虫，给予丰富的奖励。 本人就先发第一贴了。 【主题】： 仿生&矿化 【题目】：Bio-inspired Mineralization Using Hydrophilic Polymers Helmut Cofen 1 Introduction . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3 2 Different Crystallization Modes and Ways to Modify Crystallization . . . 5 2.1 ClassicalCrystallization . . . . . . . . . . . . . . . . . . . . . . . . . . . . 6 2.1.1 Thermodynamic andKineticCrystallizationPathways . . . . . . . . . . . 7 2.1.2 Face-SelectiveAdditiveAdsorption . . . . . . . . . . . . . . . . . . . . . . 10 2.2 Non-classical Crystallization. . . . . . . . . . . . . . . . . . . . . . . . . . 11 2.2.1 Oriented Attachment . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 12 2.2.2 Mesocrystals . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 14 2.2.3 Amorphous Precursors . . . . . . . . . . . . . . . . . . . . . . . . . . . . 18 2.2.4 Liquid Precursors . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 20 3 Polymer-Controlled Crystallization . . . . . . . . . . . . . . . . . . . . . . 22 3.1 Biomineralization– Some TypicalHydrophilic Polymers . . . . . . . . . . 23 3.2 Bio-inspiredMineralization . . . . . . . . . . . . . . . . . . . . . . . . . . 25 3.2.1 Biopolymers . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 26 3.2.2 Homopolymers and RandomCopolymers . . . . . . . . . . . . . . . . . . 29 3.2.3 Dendrimers . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 38 3.2.4 DoubleHydrophilic Block Copolymers (DHBCs) . . . . . . . . . . . . . . 39 3.2.5 DoubleHydrophilic GraftCopolymers (DHGCs) . . . . . . . . . . . . . . 64 Abstract Biomineralization processes result in organic/inorganic hybrid materials with complex shape, hierarchical organization, and superior materials properties. Chemistry, which is inspired by these processes, aims to mimic biomineralization principles and to transfer them to the general control of crystallization processes using an environmentally benign route. In this chapter, the latest advances in hydrophilic polymer-controlled morphosynthesis and bio-inspired mineralization of crystals are summarized with focus on the various principles that can be used to generate inorganic and organic crystals with unusual structural specialty and complexity. For this, classical crystallization pathways using crystal face-selective polymer adsorption can be applied as well as non-classical nanoparticle-mediated crystallization routes, which are based on amorphous or crystalline precursor particles. Current developments emphasize that probably all inorganic and organic crystals will be amenable to morphosynthetic control by the described strategies using either flexible polymer additives or suitable self-assembly mechanisms. The resulting unique hierarchical materials with structural specialty and complexity, and a size range spanning from nanometers to micrometers, are expected to find potential applications in various fields. In addition, bio-inspired mineralization with hydrophilic copolymers offers the chance to understand basic principles of the complex and synergetic biomineralization processes. ">【下载】------[/font] http://www.namipan.com/d/70cf41e ... 9cb2c4f0f90c9882500 [ Last edited by wgcui on 2009-2-27 at 09:53 ] |
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wgcui(金币+1,VIP+0):谢谢支持 2-28 20:10
wgcui(金币+1,VIP+0):谢谢支持 2-28 20:10
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【主题】纳米生物材料 【题目】Nanotechnology and nanomaterials: Promises for improved tissue regeneration Nano Today (2009) 4, 66—80 Summary Tissue engineering and regenerative medicine aim to develop biological substitutes that restore, maintain, or improve damaged tissue and organ functionality. While tissue engineering and regenerative medicine have hinted at much promise in the last several decades, significant research is still required to provide exciting alternative materials to finally solve the numerous problems associated with traditional implants. Nanotechnology, or the use of nanomaterials (defined as those materials with constituent dimensions less than 100 nm), may have the answers since only these materials can mimic surface properties (including topography, energy, etc.) of natural tissues. For these reasons, over the last decade, nanomaterials have been highlighted as promising candidates for improving traditional tissue engineering materials. Importantly, these efforts have highlighted that nanomaterials exhibit superior cytocompatible, mechanical, electrical, optical, catalytic and magnetic properties compared to conventional (or micron structured) materials. These unique properties of nanomaterials have helped to improve various tissue growth over what is achievable today. In this review paper, the promise of nanomaterials for bone, cartilage, vascular, neural and bladder tissue engineering applications will be reviewed. Moreover, as an important future area of research, the potential risk and toxicity of nanomaterial synthesis and use related to human health are emphasized. Keywords: Nanomaterials; Tissue engineering; Nanotechnology; Scaffold; Biomimetic; Regenerative medicine Article Outline Nanotechnology and nanomaterials: biomimetic tools for tissue regeneration The promise of nanomaterials for bone and cartilage tissue engineering applications The promise of nanomaterials for vascular tissue engineering applications The promise of nanomaterials for neural tissue engineering applications The promise of nanomaterials for bladder tissue engineering applications Potential risks of nanomaterials towards human health Conclusions References Vitae 【下载】Link: http://www.sciencedirect.com/sci ... 12bb537df232acb75ba [ Last edited by zhangwj on 2009-2-28 at 12:41 ] |
16楼2009-02-28 12:39:29
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yusen_1982(金币+1,VIP+0):好资源，支持！ 2-27 10:27
yusen_1982(金币+1,VIP+0):好资源，支持！ 2-27 10:27
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【主题】： 高分子生物材料 【题目】： MICRO AND NANO SYSTEMS IN BIOMEDICINE AND DRUG DELIVERY NESRIN HASIRCI Micro and nano sytems sysnthesized from organic and inorganic materials are gaining great attention in biomedical applications such as design of biosensors, construction of imaging systems, synthesis of drug carrying and drug targeting devices, etc. Emulsions, suspensions, micelles, liposomes, dendrimers, polymeric and responsive systems are some examples for drug carrier devices. They have lots of advantages over conventional systems since they enhance the delivery, extend the bioactivity of the drug by protecting them from environmental effects in biological media, show minimal side effects, demonstrate high performance characteristics, and are more economical since minimum amount of expensive drugs are used. This chapter provides brief information about micro and nano systems used in biomedicine, nanobiotechnology and drug delivery 【下载】 http://www.namipan.com/d/a097154 ... 3bfc1d17df2819a0300 |
2楼2009-02-27 09:56:47
3楼2009-02-27 09:57:29
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yusen_1982(金币+1,VIP+0):好资源，支持！ 2-27 10:28
yusen_1982(金币+1,VIP+0):好资源，支持！ 2-27 10:28
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【主题】：生物学评价及方法 【题目】： New Advances in Cell Adhesion Technology Santina Carnazza The main topic of this tutorial is bioadhesion, in terms of both fundamental and applied implications. First of all, we look how cells adhere to a surface and what are the mechanisms underlying adhesion of both eukaryotic and microbial cells, focusing attention mainly on the cell response to abiotic surfaces. Then, this paper will review the most recent biotechnological applications requiring the production of hybrid systems through controlled adhesion of biological components (amino acids, peptides, proteins, whole cells) onto polymers and inorganic surfaces. Biomaterials are requested with both good mechanical properties and biocompatibility. Special attention will be directed to the spatial controlled adhesion, very important in nanotechnology and bioengineering, focusing on methods and application fields. First biomedical applications, and particularly regenerative medicine (including tissue engineering), will be analyzed, in which biomaterials act as passive physical surfaces and simultaneously as active substrate for cell adhesion, migration, proliferation and differentiation. Most currently developed materials need to evoke cell adhesion and spreading, while potentially preventing bacterial colonization because bacterial adhesion to human tissues and biomaterial surface of biomedical devices is a crucial stage in infection pathogenesis. And, of course, spatially controlled cell adhesion is requested in BioMEMS applications, in particular for development of biosensors and diagnostic microsystems. Lab-on-chips and microarrays currently used will be reviewed. The main trends in the BioMEMS research are miniaturization and integration of components and the use of microtechniques to improve immobilization and spatial confinement methods. These and other applications requiring the cell/surface interaction account for considerable efforts in development of surface modification and cellular patterning methods, that are very important tools for fundamental studies in biology, especially on single cells, as well as for preparation of chip-based systems in biotechnology. Here, the main cell adhesion technologies will be discussed, and recent progress based on our research results will be briefly reported. In our laboratory, the biology of fundamental interactions between cells and materials is studied, in relation to the physico-chemical properties of the biomaterial surface. We study cell adhesion in a controlled fashion, using adhesion-supporting and -inhibiting substrata, and analyzing the subsequent cell responses. Additionally, we prepare high resolution micropatterned surfaces for the creation of organized mammalian cell patterns for applications such as biosensors and in particular single-cell arrays. New experimental data will be presented on bio-functionalization of polymer surfaces by controlled ion implantation and fibronectin adsorption aimed to enhance cell adhesion and spatial confinement.Moreover, a new technology will be proposed as an useful tool for preparation of microbial arrays that hold promise as platforms for whole-cell biosensors and diagnostic chips. Another important application for microbial arrays can be in microbial fuel cells, where there is the need for a technology that can provide, in a cost-effective manner, the large surface areas needed for the anodes and cathodes. On the other hand, the ability to obtain ordered microbial arrays with a fractal geometry could overcome problems of blocking and flux control and allow microbial biofilter use for liquid decontamination. Finally, perspectives are presented of surface bio-functionalization by phage displayed peptides, which can act as highly specific and selective probes in bioaffinity sensors, can be used in development of nanomaterials and cantilever-based nanodevices for biosensing, and can mimic ligands of cell receptors involved in signaling that affect the cellular fate. 【下载】 http://www.namipan.com/d/646c46c ... 109506bf6785a539800 |
5楼2009-02-27 10:00:44