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| Improved osseointegration of long-term stored SLA implant by hydrothermal sterilization. |
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2楼2017-05-21 13:25:26
sky蒲公英
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westlover: 金币+5 2017-05-22 08:59:26
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westlover: 金币+5 2017-05-22 08:59:26
lazy锦溪: LS-EPI+1 2017-05-22 13:52:44
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Improved osseointegration of long-term stored SLA implant by hydrothermal sterilization 作者:Shi, XL (Shi, Xingling)[ 1 ] ; Xu, LL (Xu, Lingli)[ 1 ] ; Violin, KB (Violin, Kalan Bastos)[ 2 ] ; Lu, S (Lu, Sheng)[ 1 ] JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS 卷: 53 页: 312-319 DOI: 10.1016/j.jmbbm.2015.08.038 出版年: JAN 2016 查看期刊信息 摘要 The sandblasted, large-grit and acid-etched (SLA) surface is easy to be contaminated during storage and its surface chemical state is usually changed by different sterilization methods. This causes an undesirable increase in surface hydrophobicity and results in osseointegration degradation. To overcome this problem, a low temperature hydrothermal (HT) sterilization method was proposed in this study. Briefly, 4 weeks-stored pure titanium SLA specimens were sterilized using a sealed glass bottle with pure water in an autoclave set at 121 degrees C for 20 min. Results showed that, stored SLA specimens were superhydrophobic before and after conventional autoclaving, whereas, HT sterilization decontaminated and endowed stored SLA surface with superhydrophilicity. Osteoblast spreading was greatly enhanced, ALP expression was upgraded and bone nodule formation was obviously promoted on HT sterilized specimens compared with autoclaved ones. More bone formation around HT sterilized specimens was observed and HT sterilization increased bonding strength of implant to bone by 95% and 127% after 2 and 4 weeks of healing, respectively. The simple, feasible HT sterilization restored osseointegration of SLA implant while diminishing recontamination as much as possible. Therefore, it is proposed as a standard sterilization method for implant practitioners and researches. (C) 2015 Elsevier Ltd. All rights reserved. 关键词 作者关键词:SLA implant; Hydrothermal sterilization; Autoclaving; Superhydrophilicity; Osseointegration KeyWords Plus:SURFACE-PROPERTIES; TITANIUM SURFACES; DENTAL IMPLANTS; BONE-MARROW; CELLS; BIOMATERIAL; EXPRESSION; RESPONSES 作者信息 通讯作者地址: Xu, LL (通讯作者) 显示增强组织信息的名称 Jiangsu Univ Sci & Technol, Sch Mat Sci & Engn, Zhenjiang 212003, Peoples R China. 地址: 显示增强组织信息的名称 [ 1 ] Jiangsu Univ Sci & Technol, Sch Mat Sci & Engn, Zhenjiang 212003, Peoples R China 显示增强组织信息的名称 [ 2 ] Mat Sci & Technol Ctr, Energy & Nucl Res Inst, BR-05508000 Sao Paulo, Brazil 电子邮件地址:linly311@163.com 基金资助致谢 基金资助机构 授权号 Jiangsu Provincial Key Laboratory for Interventional Medical Devices jr1418 Ph.D. programs foundation of the Jiangsu University of Science and Technology 635061402 查看基金资助信息 出版商 ELSEVIER SCIENCE BV, PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS 类别 / 分类 研究方向:Engineering; Materials Science Web of Science 类别:Engineering, Biomedical; Materials Science, Biomaterials 文献信息 文献类型:Article 语种:English 入藏号: WOS:000366226500028 PubMed ID: 26382972 ISSN: 1751-6161 eISSN: 1878-0180 其他信息 IDS 号: CY2GJ Web of Science 核心合集中的 "引用的参考文献": 27 Web of Science 核心合集中的 "被引频次": 2 |
3楼2017-05-21 13:30:17