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ÎÄÕÂ1£ºPhenolics from the roots of hairy fig (Ficus hirta Vahl.) exert prominent anti-inflammatory activity ÎÄÕÂ2£ºBenzophenones from Mango Leaves Exhibit ¦Á‑Glucosidase and NO Inhibitory Activities |
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²»»á°É£¬°Ù¶È¶¼ÄÜËѵ½µÄ£¬¿ÉÄܸñʽ²»¶Ô£¬ÄãÖØËÑһϠ1£ºCheng J, Yi X, Wang Y, et al. Phenolics from the roots of hairy fig ( Ficus hirta, Vahl.) exert prominent anti-inflammatory activity[J]. Journal of Functional Foods, 2017, 31:79-88. 2£º Pan J, Yi X, Wang Y, et al. Benzophenones from Mango Leaves Exhibit ¦Á-Glucosidase and NO Inhibitory Activities[J]. Journal of Agricultural & Food Chemistry, 2016, 64(40). |
4Â¥2017-03-08 12:30:20
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5Â¥2017-03-08 12:36:51
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µÚ¶þƪÎÄÕÂÓÐÁË£¬¸Õ¸ÕŪ´íÁË£¬²»ºÃÒâ˼¹þ/(¨Òo¨Ò)/~~ Benzophenones from Mango Leaves Exhibit alpha-Glucosidase and NO Inhibitory Activities ×÷Õß an, J (Pan, Jing)[ 1 ] ; Yi, XM (Yi, Xiaomin)[ 1 ] ; Wang, YH (Wang, Yihai)[ 1 ] ; Chen, GS (Chen, Guisi)[ 1 ] ; He, XJ (He, Xiangjiu)[ 1,2 ]JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY ¾í: 64 ÆÚ: 40 Ò³: 7475-7480 DOI: 10.1021/acs.jafc.6b02404 ³ö°æÄê: OCT 12 2016 ²é¿´ÆÚ¿¯ÐÅÏ¢ ÕªÒª Mango (Mangifera indica L.) is a succulent tropical fruit. Bioactive phytochemical investigation has been carried out to the leaves of mango. Three new benzophenone glycosides, along with 14 known compounds, were purified and identified. The novel benzophenones were elucidated to be 2,4,4',6-tetrahydroxy-3'-methoxybenzophenone-3-C-beta-D-glucopyranoside (1), 4,4',6-trihydroxybenzophenone-2-O-alpha-L-arabinofuranoside (7), and 4',6-dihydroxy-4-methoxybenzophenone-2-O-(2 ''),3-C-(1 '')-1 ''-desoxy-alpha-L-fructofuranoside (11). The alpha-glucosidase inhibitory, NO production inhibitory, and antioxidant activities were assessed for the purified benzophenones and triterpenoids. Some benzophenones showed moderate alpha-glucosidase and NO inhibitory activities. The IC50 value of the alpha-glucosidase inhibitory of isolated compounds 1, 13, and 14 were 284.93 +/- 20.29, 239.60 +/- 25.00, and 297.37 +/- 8.12 mu M, respectively. Most compounds showed moderate effects to reduce the NO content in 50 and 100 mu M. The above results of bioactivity powerfully demonstrated the phytochemicals from mango, especially benzophenones, probably partially rational for its antidiabetes and anti-inflammatory. ¹Ø¼ü´Ê ×÷Õ߹ؼü´Ê:mango; Mangifera indica; benzophenones; alpha-glucosidase inhibitory; antioxidant; anti-inflammatory KeyWords Plus:MANGIFERA-INDICA L.; MASS-SPECTROMETRY; DERIVATIVES; GLYCOSIDES; CONSTITUENTS; VARIETIES ×÷ÕßÐÅÏ¢ ͨѶ×÷ÕßµØÖ·: Wang, YH; He, XJ (ͨѶ×÷Õß) [ÏÔʾÔöÇ¿×éÖ¯ÐÅÏ¢µÄÃû³Æ] Guangdong Pharmaceut Univ, Sch Pharm, Guangzhou Higher Educ Mega Ctr, 280 East Outer Ring Rd, Guangzhou 510006, Guangdong, Peoples R China. ͨѶ×÷ÕßµØÖ·: He, XJ (ͨѶ×÷Õß) State Adm TCM, Key Lab Digital Qual Evaluat Chinese Mat Med, Guangzhou 510006, Guangdong, Peoples R China. µØÖ·: [ÏÔʾÔöÇ¿×éÖ¯ÐÅÏ¢µÄÃû³Æ] [ 1 ] Guangdong Pharmaceut Univ, Sch Pharm, Guangzhou Higher Educ Mega Ctr, 280 East Outer Ring Rd, Guangzhou 510006, Guangdong, Peoples R China [ 2 ] State Adm TCM, Key Lab Digital Qual Evaluat Chinese Mat Med, Guangzhou 510006, Guangdong, Peoples R China µç×ÓÓʼþµØÖ·:wangyih88@163.com; hexiangjiu@163.com »ù½ð×ÊÖúÖÂл »ù½ð×ÊÖú»ú¹¹ ÊÚȨºÅ project of Guangdong Provincial Department of Science and Technology 2015A020211027 Guangdong Natural Science Foundation 2014A030313588 ²é¿´»ù½ð×ÊÖúÐÅÏ¢ ³ö°æÉÌ AMER CHEMICAL SOC, 1155 16TH ST, NW, WASHINGTON, DC 20036 USA Àà±ð / ·ÖÀà Ñо¿·½Ïò:Agriculture; Chemistry; Food Science & Technology Web of Science Àà±ð:Agriculture, Multidisciplinary; Chemistry, Applied; Food Science & Technology ÎÄÏ×ÐÅÏ¢ ÎÄÏ×ÀàÐÍ:Article ÓïÖÖ:English Èë²ØºÅ: WOS:000385469900008 PubMed ID: 27643634 ISSN: 0021-8561 eISSN: 1520-5118 ÆÚ¿¯ÐÅÏ¢ Impact Factor (Ó°ÏìÒò×Ó): Journal Citation Reports® ÆäËûÐÅÏ¢ IDS ºÅ: DY9QJ Web of Science ºËÐĺϼ¯ÖÐµÄ "ÒýÓõIJο¼ÎÄÏ×": 30 Web of Science ºËÐĺϼ¯ÖÐµÄ "±»ÒýƵ´Î": 0 |

6Â¥2017-03-08 12:38:07
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Benzophenones from Mango Leaves Exhibit alpha-Glucosidase and NO Inhibitory Activities ×÷Õß an, J (Pan, Jing)[ 1 ] ; Yi, XM (Yi, Xiaomin)[ 1 ] ; Wang, YH (Wang, Yihai)[ 1 ] ; Chen, GS (Chen, Guisi)[ 1 ] ; He, XJ (He, Xiangjiu)[ 1,2 ]JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY ¾í: 64 ÆÚ: 40 Ò³: 7475-7480 DOI: 10.1021/acs.jafc.6b02404 ³ö°æÄê: OCT 12 2016 ²é¿´ÆÚ¿¯ÐÅÏ¢ ÕªÒª Mango (Mangifera indica L.) is a succulent tropical fruit. Bioactive phytochemical investigation has been carried out to the leaves of mango. Three new benzophenone glycosides, along with 14 known compounds, were purified and identified. The novel benzophenones were elucidated to be 2,4,4',6-tetrahydroxy-3'-methoxybenzophenone-3-C-beta-D-glucopyranoside (1), 4,4',6-trihydroxybenzophenone-2-O-alpha-L-arabinofuranoside (7), and 4',6-dihydroxy-4-methoxybenzophenone-2-O-(2 ''),3-C-(1 '')-1 ''-desoxy-alpha-L-fructofuranoside (11). The alpha-glucosidase inhibitory, NO production inhibitory, and antioxidant activities were assessed for the purified benzophenones and triterpenoids. Some benzophenones showed moderate alpha-glucosidase and NO inhibitory activities. The IC50 value of the alpha-glucosidase inhibitory of isolated compounds 1, 13, and 14 were 284.93 +/- 20.29, 239.60 +/- 25.00, and 297.37 +/- 8.12 mu M, respectively. Most compounds showed moderate effects to reduce the NO content in 50 and 100 mu M. The above results of bioactivity powerfully demonstrated the phytochemicals from mango, especially benzophenones, probably partially rational for its antidiabetes and anti-inflammatory. ¹Ø¼ü´Ê ×÷Õ߹ؼü´Ê:mango; Mangifera indica; benzophenones; alpha-glucosidase inhibitory; antioxidant; anti-inflammatory KeyWords Plus:MANGIFERA-INDICA L.; MASS-SPECTROMETRY; DERIVATIVES; GLYCOSIDES; CONSTITUENTS; VARIETIES ×÷ÕßÐÅÏ¢ ͨѶ×÷ÕßµØÖ·: Wang, YH; He, XJ (ͨѶ×÷Õß) ÏÔʾÔöÇ¿×éÖ¯ÐÅÏ¢µÄÃû³Æ Guangdong Pharmaceut Univ, Sch Pharm, Guangzhou Higher Educ Mega Ctr, 280 East Outer Ring Rd, Guangzhou 510006, Guangdong, Peoples R China. ͨѶ×÷ÕßµØÖ·: He, XJ (ͨѶ×÷Õß) State Adm TCM, Key Lab Digital Qual Evaluat Chinese Mat Med, Guangzhou 510006, Guangdong, Peoples R China. µØÖ·: ÏÔʾÔöÇ¿×éÖ¯ÐÅÏ¢µÄÃû³Æ [ 1 ] Guangdong Pharmaceut Univ, Sch Pharm, Guangzhou Higher Educ Mega Ctr, 280 East Outer Ring Rd, Guangzhou 510006, Guangdong, Peoples R China [ 2 ] State Adm TCM, Key Lab Digital Qual Evaluat Chinese Mat Med, Guangzhou 510006, Guangdong, Peoples R China µç×ÓÓʼþµØÖ·:wangyih88@163.com; hexiangjiu@163.com »ù½ð×ÊÖúÖÂл »ù½ð×ÊÖú»ú¹¹ ÊÚȨºÅ project of Guangdong Provincial Department of Science and Technology 2015A020211027 Guangdong Natural Science Foundation 2014A030313588 ²é¿´»ù½ð×ÊÖúÐÅÏ¢ ³ö°æÉÌ AMER CHEMICAL SOC, 1155 16TH ST, NW, WASHINGTON, DC 20036 USA Àà±ð / ·ÖÀà Ñо¿·½Ïò:Agriculture; Chemistry; Food Science & Technology Web of Science Àà±ð:Agriculture, Multidisciplinary; Chemistry, Applied; Food Science & Technology ÎÄÏ×ÐÅÏ¢ ÎÄÏ×ÀàÐÍ:Article ÓïÖÖ:English Èë²ØºÅ: WOS:000385469900008 PubMed ID: 27643634 ISSN: 0021-8561 eISSN: 1520-5118 |

7Â¥2017-03-08 12:39:18













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an, J (Pan, Jing)[ 1 ] ; Yi, XM (Yi, Xiaomin)[ 1 ] ; Wang, YH (Wang, Yihai)[ 1 ] ; Chen, GS (Chen, Guisi)[ 1 ] ; He, XJ (He, Xiangjiu)[ 1,2 ]