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★ ★ ★ ★ ★ kqy920(金币+5):谢谢分享!欢迎常来!
【姓 名】:Dr. Chad Mirkin
【研究方向】: Main research areas:
Dr. Chad A. Mirkin's research focuses on developing methods for controlling the architecture of molecules and materials on the 1-100 nm length scale, and utilizing such structures in the development of analytical tools that can be used in the areas of chemical and biological sensing, lithography, catalysis, and optics. Mirkin has pioneered the use of biomolecules as synthons in materials science and the development of nanoparticle-based biodiagnostics. Many of the concepts and materials developed within his laboratories are now the basis for commercial detection and lithography systems.
【Publications】:
Huo, F.; Zheng, Z.; Zheng, G.; Giam L. R.; Zhang, H.; Mirkin, C. A. “Polymer Pen Lithography” Science 2008, online DOI: 10.1126/science.1162193 (pdf reprint)
Kuwabara, J.; Ovchinnikov, M. V.; Stern, C. L.; Mirkin, C. A. “The Reactivity of Dinuclear Rhodium(I) Macrocycles Formed via the Weak-Link Approach,” Organometallics 2008, 27, 789-792.
Kim, K.-H.; Sanedrin, K.; Ho, A. M.; Lee, S.-W.; Moldovan, N.; Mirkin, C. A.; Espinosa, H. D. “Direct Delivery and Submicrometer Patterning of DNA by a Nanofountain Probe,” Adv. Mater. 2008, 20, 330-334.
Lee, J.-S.; Ulmann, P. A.; Han, M. S.; Mirkin, C. A. “A DNA-Gold Nanoparticle Based Colorimetric Competition Assay for the Detection of Cysteine,“ Nano Lett. 2008, 8, 529-533.
Ciszek, J. W.; Huang, L.; Wang, Y.; Mirkin, C. A. “Kinetically-Controlled, Shape-Directed Assembly of Nanorods,“ Small 2008, 4, 206-210.
Park, S. Y.; Lytton-Jean, A. K. R.; Lee, B.; Weigand, S.; Schatz, G. C.; Mirkin, C. A. “DNA-Programmable Nanoparticle Crystallization,“ Nature 2008, 451, 553-556.
Oliveri, C. G.; Nguyen, S.; Mirkin, C. A. “A Highly Modular and Convergent Approach for the Synthesis of Stimulant-Responsive Heteroligated Cofacial Porphyrin Tweezer Complexes,” Inorg. Chem. 2008, 47, 2755-2763.
Sanedrin, R. G.; Huang, L.; Jang, J.-W.; Kakkassery, J.; Mirkin, C. A. “Polyethylene Glycol as a Novel Resist and Sacrificial Material for Generating Positive and Negative Nanostructures,“ Small 2008, in press.
Zheng, G.; Qin, L.; Mirkin, C. A. “Spectroscopically Enhancing Electrical Nanotraps,” Angew. Chem. Int. Ed. 2008, 47, 1938-1941.
Lithography-Based Molecular Transport Junctions: A New Testbed for Molecular Electronics“ J. Am. Chem. Soc. 2008, in press.
Xue, C.; Metraux, G. S.; Millstone, J. E.; Mirkin, C. A. “A Mechanistic Study of Photomediated Triangular Silver Nanoprism Growth” J. Am. Chem. Soc. 2008, in press.
Banholzer, M. J.; Millstone, J. E.; Mirkin, C. A. “Rationally Designed Nanostructures for Surface Enhanced Raman Spectroscopy,“ Chemical Society Reviews 2008, 37, 885-897.
Banholzer, M. J.; Millstone, J. E.; Mirkin, C. A. “On-Wire Lithography: Designing Nanostructures with Optimal SERS Behavior,“ SPIE Newsroom (Online 2008), April 25, 2008. http://spie.org/x24237.xml (accessed May 5, 2008).
Xu, X.; Zhao, Z.; Qin, L.; Wei, W.; Levine, J. E.; Mirkin, C. A. “A Fluorescence Recovery Assay for the Detection of Protein - DNA Binding,“ Analytical Chem. 2008, in press.
Oliveri, C. G.; Ulmann, P. A.; Wiester, M. J.; Mirkin, C. A. “Heteroligated Supramolecular Coordination Complexes Formed via the Halide Induced Ligand Rearrangement Reaction,“ Acc. Chem. Res. 2008, in press.
Lee, J.-S.; Seferos, D. S.; Giljohann, D. A.; Mirkin, C. A. “Synthesis, Thermodynamically Controlled Separation, and Characterization of Polyvalent 2-nm Gold Nanoparticle-Oligonucleotide Conjugates,” J. Am. Chem. Soc. 2008, 130, 5430-5431.
Jeon, Y.-M.; Heo, J.; Mirkin, C. A. “Amorphous Infinite Coordination Polymer Microparticles: A New Class of Selective Hydrogen Storage Materials,” Adv. Materials 2008, 20, 2105-2110.
Jang, J.-W.; Sanedrin, R.; Maspoch, D.; Hwang, S.; Fujigaya, T.; Jeon, Y.-M.; Vega, R.; Chen, X.; Mirkin, C. A. ”Electrically Biased Nanolithography with KOH Coated AFM Tips,” Nano Lett. 2008, 8, 1451-1455.
Jeon, Y.-M.; Kim, D.; Mirkin, C. A.; Golen, J. A.; Rheingold, A. L. ”Pyrene-Appended Fluorescent Tweezers Generated via the Weak-Link Approach,” Tetrahedron 2008, in press.
Bae, Y.-S.; Farha, O. K.; Spokoynyy, A. M.; Mirkin, C. A.; Hupp, J. T.; Snurr, R. Q. “Carborane-Based Metal-Organic Frameworks as Highly Selective Sorbents for CO2 over Methane,” ChemComm 2008, in press
Giljohann, D. A.; Mirkin, C. A. “Tiny Tiles, Tiny Targets,“ Nature Biotechnology 2008, 26, 299-300.
Hill, H. D.; Macfarlane, R. J.; Senesi, A. J.; Lee, B.; Park, S. Y.; Mirkin, C. A. “Controlling the Lattice Parameters of Gold Nanoparticle FCC Crystals with Duplex DNA Linkers,“ Nano Lett. 2008, in press.
Lenhert, S.; Sun, P.; Wang, Y.; Fuchs, H.; Mirkin, C. A. “Massively Parallel Dip-Pen Nanolithography of Heterogeneous Supported Phospholipid Multilayer Patterns,” Small, 2007, 3, 71-75.
Xue, C.; Mirkin, C. A. “pH-Switchable Silver Nanoprism Growth Pathways,” Angew. Chem. Int. Ed. 2007, 46, 2036-2038.
Zhou, S.; Maspoch, D.; Wang, Y.; Mirkin, C. A.; Schatz, G. C. “Rings of Single-Walled Carbon Nanotubes: Molecular-Template Directed Assembly and Monte-Carlo Modeling,” Nano Letters, 2007, 7, 276-280.
Jeon, Y.-M.; Heo, J.; Mirkin, C. A. “Acid-Functionalized Dissymmetric Salen Ligands and Their Manganese (III) Complexes,” Tetrahedron Lett. 2007, 48, 2591-2595.
Salaita, K. S.; Wang, Y.; Mirkin, C. A. “Applications of Dip-Pen Nanolithography,” Nature Nanotech. 2007, 2, 145-155.
Jang, J.-W., Maspoch, D.; Fujigaya, T.; Mirkin, C. A. “A Molecular Eraser for Dip-Pen Nanolithography,” Small 2007, 3, 600-605.
Ulmann, P. A.; Brown, A. M.; Ovchinnikov, M. V.; Mirkin, C. A.; DiPasquale, A. G.; Rheingold, A. L. “Spontaneous Formation of Heteroligated PtII Complexes with Chelating Hemilabile Ligands,” Chemistry – A European Journal 2007, 13, 4529-4534.
Xu, X.; Han, M. S.; Mirkin, C. A. “A Gold Nanoparticle-Based, Real-Time Colorimetric Screening Method for Endonuclease Activity and Inhibition,” Angew. Chem. Int. Ed. 2007, 46, 3468-3470.
Lee, J.-S.; Han, M. S.; Mirkin, C. A. “Colorimetric Detection of Mercuric Ion (Hg2+) in Aqueous Media Using DNA-Functionalized Gold Nanoparticles,” Angew. Chem. Int. Ed. 2007, 46, 4093-4096.
Jeon, Y.-M.; Heo, J.; Mirkin, C. A. “Dynamic Interconversion of Amorphous Microparticles and Crystalline Rods in Salen-based Homochiral Infinite Coordination Polymers,” J. Am. Chem. Soc. 2007, 129, 7480-7481.
Masar, M. S. III; Gianneschi, N. C.; Oliveri, C. G.; Stern, C. L.; Nguyen, S. T.; Mirkin, C. A. “Allosterically Regulated Supramolecular Catalysis of Acyl Transfer Reactions for Signal Amplification and Detection of Small Molecules,” J. Am. Chem. Soc. 2007, 129, 10149-10158.
Heo, J.; Jeon, Y.-M.; Mirkin, C. A. “Reversible Interconversion of Homochiral Triangular Macrocycles and Helical Coordination Polymers,” J. Am. Chem. Soc. 2007, 129, 7712-7713.
Lytton-Jean, A. K. R.; Han, M. S.; Mirkin, C.A. “Microarray Detection of Duplex and Triplex DNA Binders with DNA-Modified Gold Nanoparticles,” Analytical Chem. 2007, 79, 6037-6041.
Vega, R. A.; Shen, C. K.-F.; Maspoch, D.; Robach, J. G.; Lamb, R. A.; Mirkin, C. A. “Monitoring Single Cell Infectivity from Virus Particle Nanoarrays Fabricated by Parallel Dip-Pen Nanolithography,” Small 2007, 3, 1482-1485.
Hurst, S. J.; Han, M. S.; Lytton-Jean, A. K. R.; Mirkin, C. A. “Screening the Sequence Selectivity of DNA-Binding Molecules Using a Gold Nanoparticle-based Colorimetric Approach,” Analytical Chemistry 2007, 79, 7201-7205.
Seferos, D. S.; Giljohann, D. A.; Rosi, N. L.; Mirkin, C. A. “Locked Nucleic Acid-Nanoparticle Conjugates,”ChemBioChem. 2007, 8, 1230-1232.
Xu, X.; Georganopoulou, D. G.; Hill, H. D.; Mirkin, C. A. “Homogeneous Detection of Nucleic Acids Based upon the Light Scattering Properties of Silver-Coated Nanoparticle Probes,” Analytical Chem. 2007, 79, 6650-6654.
Tang, S.; Zhao, J.; Storhoff, J. J.; Norris, P. I.; Little, R. F.; Yarchoan, R.; Stramer, S. L.; Patno, T.; Domanus, M.; Bernal, Y.; Dhar, A.; Mirkin, C. A.; Hewlett, I.
“Nanoparticle Based Biobarcode Amplification Assay (BCA) for Sensitive and Early Detection of Human Immunodeficiency Type 1 Capsid (p24) Antigen,” J. Aids 2007, 46, 231-237.
Lee, J.-S.; Lytton-Jean, A. K. R.; Hurst, S.; Mirkin, C. A. “Silver Nanoparticle Oligonucleotide Conjugates Based on Triple Cyclic Disulfide Moieties,” Nano Lett. 2007, 7, 2112-2115.
Kuwabara, J.; Stern, C. L.; Mirkin, C. A. “A Coordination Chemistry Approach to a Multieffector Enzyme Mimic,” J. Am. Chem. Soc. 2007, 129, 10074-10075.
Qin, L.; Banholzer, M. J.; Millstone, J. E.; Mirkin, C. A. “Nanodisk Codes,“ Nano Lett. 2007, 7, 3849-3853.
Oliveri, C. G.; Heo, J.; Nguyen, S. T.; Mirkin, C. A.; Wawrzak, Z. “A Convergent Coordination Chemistry-Based Approach to Dissymmetric Macrocyclic Cofacial Porphyrin Complexes,” Inorganic Chem. 2007, 46, 7716-7718.
Xue, C.; Chen, X.; Hurst, S. J.; Mirkin, C. A. “Self-Assembled Monolayer Mediated Silica Coating of Silver Triangular Nanoprisms,” Adv. Mater. 2007, 19, 4071-4074.
Hill, H. D.; Vega, R. A.; Mirkin, C. A. “Non-Enzymatic Detection of Bacterial Genomic DNA Using the Bio-Barcode Assay,“ Analytical Chem. 2007, 79, 9218-9223.
Xue, C.; Millstone, J. E.; Mirkin, C. A. “Plasmon-Driven Synthesis of Triangular Nanoprisms from Isotropic Gold Cores,” Angew. Chem. Int. Ed. 2007, 46, 8436-8439.
Giljohann, D. A.; Seferos, D. S.; Patel, P. C.; Millstone, J. E.; Rosi, N. L.; Mirkin, C. A. “Oligonucleotide Loading Determines Cellular Uptake of DNA-Modified Nanoparticles,“ Nano Lett. 2007, 7, 3818-3821.
Seferos, D. S.; Giljohann, D. A.; Hill, H. D.; Prigodich, A. E.; Mirkin, C. A. “Nanoflares: Probes for Transfection, RNA Visualization, and Detection of Transcripts in Living Cells,” J. Am. Chem. Soc. 2007, 129, 15477-15479.
Farha, O. K.; Spokoyny, A. M.; Mulfort, K. L.; Hawthorne, M. F.; Mirkin, C. A.; Hupp, J. T. “Synthesis and Hydrogen Sorption Properties of Carborane-Based Metal-Organic Framework Materials,” J. Am. Chem. Soc. 2007, 129, 12680-12681.
Mirkin, C. A. “The Power of the Pen: Development of Massively Parallel Dip-Pen Nanolithography,” ACS Nano 2007, 1, 79-83.
Qin, L.; Banholzer, M. J.; Xu, X.; Huang, L.; Mirkin, C. A. “Rational Design and Synthesis of Catalytically Driven Nano Rotors,” J. Am. Chem. Soc. 2007, 129, 14870-14871.
Yoon, H. J.; Heo, J.; Mirkin, C. A. “Allosteric Regulation of Phosphate Diester Transesterification Based Upon a Dinuclear Zinc Catalyst Assembled via the Weak-Link Approach,” J. Am. Chem. Soc. 2007, 129, 14182-14183.
[ Last edited by kinmer on 2009-1-1 at 11:47 ] |
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