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[交流] 王红阳综述|Cancer prevention and control: alarming challenges in China

Cancer prevention and control: alarming challenges in China

Ann M. Bode, Zigang Dong and Hongyang Wang

ABSTRACT
China is geographically the third largest country in the world and the most populated
low-to-middle-income country. Cancer incidence and mortality rates for some cancers in the USA and
European countries have steadily decreased over the last decades, whereas the incidence and mortality of
certain cancers in China have been increasing at an alarming speed. Rapid industrialization and
urbanization in China have been accompanied by incredible changes in lifestyle and environment
combined with an aging population. Mortality caused by lung, colorectal and breast cancers has been
steadily increasing, whereas cancer mortality from gastric, esophageal and cervical tumors has tended to
decrease. Similar to what has occurred in the United States, unhealthy lifestyles in China, including heavy
smoking and poor diet combined with pollution, have contributed to increased cancer risk. China is facing
many challenges in cancer treatment and prevention for the general population. The major areas that need
to be addressed in the control of cancer in China include cancers associated with environmental pollution,
tobacco use, occupational carcinogens, infection, excessive alcohol consumption, dietary deficiencies and
obesity. In this perspective, we review the problems in each area and suggest ideas for future directions in
cancer research and strategies and actions to reduce the incidence of cancer in China.

Keywords: cancer incidence, environmental pollution, tobacco use and control, occupational carcinogens,
infection-caused cancers, alcohol, dietary deficiencies, obesity, cancer prevention
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