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609718476

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跪求Silymarin versus Silibinin: Differential Antioxidant and Neuroprotective Effects against H2O2-induced Oxidative Stress in PC12 Cells.这篇文章的检索号!
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muchong_li

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609718476: 金币+2, 有帮助 2016-10-28 11:30:10
Nat Prod Commun.  2016; 11(5):633-6 (ISSN: 1934-578X)
2楼2016-10-28 11:00:11
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wangxiaomail

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609718476: 金币+12, ★★★★★最佳答案 2016-10-28 11:30:28
Silymarin versus Silibinin: Differential Antioxidant and Neuroprotective Effects against H2O2-induced Oxidative Stress in PC12 Cells
作者:Jiang, HH (Jiang, Hui-Hui)[ 1 ] ; Yan, FS (Yan, Fa-Shun)[ 1 ] ; Shen, L (Shen, Liang)[ 1 ] ; Ji, HF (Ji, Hong-Fang)[ 1 ]
NATURAL PRODUCT COMMUNICATIONS
卷: 11  期: 5  页: 633-636
出版年: MAY 2016
查看期刊信息
摘要
The present study assessed comparatively the antioxidant activities of silymarin and its major active component silibinin and their neuroprotective effects against hydrogen peroxide (H2O2)-induced oxidative stress in rat pheochromocytoma PC12 cells. It was found that despite newly prepared silymarin and silibinin solution possessing comparable superoxide anion (O-2(center dot-))-scavenging activities, with time the activity of silymarin lowered slightly, but that of silibinin decreased dramatically. Both silymarin and silibinin suppressed H2O2 -induced oxidative stress and apoptosis, and the neuroprotective effect of silymarin was overall relatively stronger than that of silibinin. The findings provided clues for future studies on therapeutic potentials of the whole silymarin or purified silibinin for neurodegenerative diseases.
关键词
作者关键词:Silymarin; Silibinin; Neurodegenerative diseases; Neuroprotective effects; PC12 cells
KeyWords Plus:THISTLE SILYBUM-MARIANUM; PARKINSONS-DISEASE; ALZHEIMERS-DISEASE; MILK THISTLE; NEURODEGENERATIVE DISEASES; MECHANISMS; MODEL; PREVALENCE; DISORDERS; APOPTOSIS
作者信息
通讯作者地址: Shen, L; Ji, HF (通讯作者)
显示增强组织信息的名称        Shandong Univ Technol, Sch Life Sci, Shandong Prov Res Ctr Bioinformat Engn & Tech, Zibo 255049, Peoples R China.
地址:
显示增强组织信息的名称        [ 1 ] Shandong Univ Technol, Sch Life Sci, Shandong Prov Res Ctr Bioinformat Engn & Tech, Zibo 255049, Peoples R China
电子邮件地址:shen@sdut.edu.cn; jhf@sdut.edu.cn
基金资助致谢
基金资助机构        授权号
Shandong Provincial Science Foundation for Distinguished Young Scholars        
JQ201508
Shandong Provincial Science Foundation        
ZR2015JL010
ZR2014CL008
查看基金资助信息   
出版商
NATURAL PRODUCTS INC, 7963 ANDERSON PARK LN, WESTERVILLE, OH 43081 USA
类别 / 分类
研究方向harmacology & Pharmacy; Food Science & Technology
Web of Science 类别:Chemistry, Medicinal; Food Science & Technology
文献信息
文献类型:Article
语种:English
入藏号: WOS:000375633500020
PubMed ID: 27319137
ISSN: 1934-578X
eISSN: 1555-9475
期刊信息
目录: Current Contents Connect®
Impact Factor (影响因子): Journal Citation Reports®
其他信息
IDS 号: DL4UO
Web of Science 核心合集中的 "引用的参考文献": 32
Web of Science 核心合集中的 "被引频次": 0
3楼2016-10-28 11:14:58
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wangxiaomail

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609718476: 金币+6, ★★★很有帮助 2016-10-28 11:30:37
检索号通常是指WOS或者IDS,这篇文章的如下:

WOS: 000375633500020

IDS 号: DL4UO
4楼2016-10-28 11:18:00
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