[交流] 有人在0℃下用stober法在磁性微球表面用TEOS包裹二氧化硅的吗？ 已有3人参与

Afterward, the preparation of Fe3O4@SiO2@NH2 core/shell microspheres was carried out by the Stober process27 with minor changes. The synthesized magnetic nanoparticles (0.040 g) were homogeneously dispersed in a mixture containing ethanol (128 mL), deionized water (36 mL), and 28% (wt) concentrated ammonia aqueous solution (NH3·H2O), followed by the addition of 0.20 g of tetraethyl orthosilicate (TEOS). Then, the reaction was allowed to proceed at 0 °C for 1 hunder sonication to get the silica embedded magnetic nanoparticles. Finally, 0.020 g of 3-aminopropyl-triethoxysilane (APTES) was added to the above mixture, and the reaction was performed for another 20 min under sonication. The harvested Fe3O4@SiO2@NH2 microspheres were collected with a magnet and washed repeatedly with ethanol and water to effectively remove nonmagnetic byproducts and residual reagents. The final products were dried under vacuum at 50 °C for further use. 看见 Analytical Chemistry上 在0℃下合成的，有试过这样合成的同学吗？ 文章题目是：An Accessible Protocol for Solid-Phase Extraction of N‑Linked Glycopeptides through Reductive Amination by AmineFunctionalized Magnetic Nanoparticles

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